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Infectious Disease: Parasitic Diseases
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Total 613 results found since Jan 2013.
NIH scientists develop new tests to detect drug-resistant malaria
(NIH/National Institute of Allergy and Infectious Diseases) Researchers have developed two tests that can discern within three days whether the malaria parasites in a given patient will be resistant or susceptible to artemisinin, the key drug used to treat malaria. The tests were developed by researchers from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, working with French and Cambodian colleagues in Cambodia.
Source: EurekAlert! - Infectious and Emerging Diseases - September 10, 2013 Category: Infectious Diseases Source Type: news
Researchers identify genetic marker of resistance to key malaria drug
(NIH/National Institute of Allergy and Infectious Diseases) An international team of researchers has discovered a way to identify, at a molecular level, malaria-causing Plasmodium falciparum parasites that are resistant to artemisinin, the key drug for treating this disease. The research team, which included scientists from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, published their findings today in the journal Nature.
Source: EurekAlert! - Medicine and Health - December 18, 2013 Category: Global & Universal Source Type: news
Induction of regulatory cells by helminth parasites: exploitation for the treatment of inflammatory diseases
Summary
Helminth parasites are highly successful pathogens, chronically infecting a quarter of the world's population, causing significant morbidity but rarely causing death. Protective immunity and expulsion of helminths is mediated by T‐helper 2 (Th2) cells, type 2 (M2) macrophages, type 2 innate lymphoid cells, and eosinophils. Failure to mount these type 2 immune responses can result in immunopathology mediated by Th1 or Th17 cells. Helminths have evolved a wide variety of approaches for immune suppression, especially the generation of regulatory T cells and anti‐inflammatory cytokines interleukin‐10 and transfor...
Source: Immunological Reviews - April 9, 2014 Category: Allergy & Immunology Authors: Conor M. Finlay, Kevin P. Walsh, Kingston H. G. Mills Tags: Invited Review Source Type: research
Anisakis/Ascaris IgE ratio improves specificity for the diagnosis of Anisakis simplex sensitization in travellers and immigrants.
In conclusion, the ratio of specific IgE to Anisakis and Ascaris improved remarkably the specificity and this parameter easily obtained from the commercially available system could be useful in the diagnosis of hypersensitivity to Anisakis simplex.
PMID: 24911935 [PubMed - as supplied by publisher]
Source: Acta Tropica - June 6, 2014 Category: Infectious Diseases Authors: Carballeda-Sangiao N, Rodríguez-Mahillo AI, Puente S, Gutiérrez MT, Moneo I, González-Muñoz M Tags: Acta Trop Source Type: research
Mucosal immune responses following intestinal nematode infection
Summary
In most natural environments, the large majority of mammals harbour parasitic helminths that often live as adults within the intestine for prolonged periods (1–2 years) . Although these organisms have been eradicated to a large extent within westernized human populations, those living within rural areas of developing countries continue to suffer from high infection rates. Indeed, recent estimates indicate that approximately 2·5 billion people worldwide, mainly children, currently suffer from infection with intestinal helminths (also known as geohelminths and soil‐transmitted helminths) . Paradoxically, the e...
Source: Parasite Immunology - September 8, 2014 Category: Parasitology Authors: C. Zaph, P. J. Cooper, N. L. Harris Tags: Review Article Source Type: research
Mobile phone microscope rapidly detects parasite levels in blood
(NIH/National Institute of Allergy and Infectious Diseases) Scientists from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, and the University of California, Berkeley, and colleagues have developed a mobile phone microscope to measure blood levels of the parasitic filarial worm Loa loa. The point-of-care device may enable safe resumption of mass drug administration campaigns to eradicate the parasitic diseases onchocerciasis (river blindness) and lymphatic filariasis (elephantiasis).
Source: EurekAlert! - Infectious and Emerging Diseases - May 6, 2015 Category: Infectious Diseases Source Type: news
Smartphone app used to scan blood for parasites
Conclusion
This study suggests a new smartphone-based approach could provide a quick way of measuring levels of infection with the Loa loa worm in blood samples, and with a high level of accuracy.
This technique could allow assessment of people's infection in communities without easy access to the laboratory testing that is usually used to detect the worms.
This is important, as people with high levels of this infection can suffer potentially fatal side effects with the drug ivermectin, which is used to treat two other parasitic infections.
It's worth bearing in mind that this was a pilot study in only 33 people using a ...
Source: NHS News Feed - May 7, 2015 Category: Consumer Health News Tags: Medical practice Source Type: news
10 Essential Facts About Lyme Disease
By Allison Pohle for Everyday Health Every year, U.S. state health departments report about 30,000 cases of Lyme disease to the Centers for Disease Control and Prevention (CDC). But the CDC says the true number of cases in the United States could be ten times as high. Lyme disease is transmitted to humans from tick bites. The ticks that transmit the disease are most active from April to September, which means spring and summer are the prime times for infection. With the right steps, and regular tick checks, however, you can prevent Lyme disease. Here are 10 things you should know about this tickborne disease: 1. You can on...
Source: Healthy Living - The Huffington Post - August 8, 2015 Category: Consumer Health News Source Type: news
Gene sequences reveal global variations in malaria parasites
(NIH/National Institute of Allergy and Infectious Diseases) Plasmodium vivax (P. vivax) parasites, which cause a debilitating form of malaria, are yielding their secrets to an international team of researchers funded by the National Institute of Allergy and Infectious Diseases. In the largest such effort to date, the team determined complete genomes of nearly 200 P. vivax strains that recently infected people in eight countries.
Source: EurekAlert! - Infectious and Emerging Diseases - June 27, 2016 Category: Infectious Diseases Source Type: news
NIH explores connection between Ebola survival and co-infection with malaria parasites
(NIH/National Institute of Allergy and Infectious Diseases) People infected with Ebola virus were 20 percent more likely to survive if they were co-infected with malaria-causing Plasmodium parasites, according to data collected at an Ebola diagnostic laboratory in Liberia in 2014-15. Moreover, greater numbers of Plasmodium parasites correlated with increased rates of Ebola survival, according to the new study. Scientists from the National Institute of Allergy and Infectious Diseases, part the National Institutes of Health, led the project.
Source: EurekAlert! - Infectious and Emerging Diseases - August 16, 2016 Category: Infectious Diseases Source Type: news
IgE sensitization to Anisakis pegreffii in Italy: comparison of two methods for the diagnosis of allergic anisakiasis
This article is protected by copyright. All rights reserved.
Source: Parasite Immunology - May 5, 2017 Category: Parasitology Authors: S. Mattiucci, A. Colantoni, B. Crisafi, F. Mori ‐Ubaldini, L. Caponi, P. Fazii, G. Nascetti, F. Bruschi Tags: Original Paper Source Type: research
Modified experimental vaccine protects monkeys from deadly malaria
(NIH/National Institute of Allergy and Infectious Diseases) Researchers from the National Institute of Allergy and Infectious Diseases (NIAID), part of NIH, modified an experimental malaria vaccine and showed that it completely protected four of eight monkeys that received it against challenge with the virulent Plasmodium falciparum malaria parasite. In three of the remaining four monkeys, the vaccine delayed when parasites first appeared in the blood by more than 25 days.
Source: EurekAlert! - Infectious and Emerging Diseases - May 22, 2017 Category: Infectious Diseases Source Type: news
How Common Is Hereditary Angioedema?
Discussion
Angioedema is edema that is non-pitting, self-limited occurring in non-dependent areas usually in an asymmetric distribution usually on the lips, face, hands, feet, genitals and also in the bowel. It usually develops over minutes to hours (often 1-2 hours) with resolution usually within 24-48 hours. Angioedema often occurs with urticaria but 20% of patients may have isolated angioedema. Acute allergic angioedema is often caused by drugs (including antibiotics and non-steroidal anti-inflammatory drugs), foods, infections, insects, various organic substances (i.e. latex, preservatives, formaldehyde, etc.), and oth...
Source: PediatricEducation.org - October 9, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news
Diagnosis and Treatment of Canine Acral Lick Dermatitis
Acral lick dermatitis is a common, frustrating disease. It is characterized by incessant licking behavior resulting in raised, thickened, ulcerative plaques, most commonly affecting the lower extremities of dogs. Underlying primary diseases, such as allergic disorders (atopic dermatitis, food allergy, flea allergy), orthopedic or neurologic disorders, parasitic diseases (eg, demodicosis), infections (fungal, bacterial), neoplasia or psychogenic disorders (compulsive/obsessive-compulsive disorder), and perpetuating factors (especially secondary infections) drive the itch-lick cycle. Appropriately addressing the primary unde...
Source: Veterinary Clinics of North America: Small Animal Practice - September 26, 2018 Category: Veterinary Research Authors: Amy K. Shumaker Source Type: research
Human health, legislative and socioeconomic issues caused by the fish-borne zoonotic parasite Anisakis: challenges in risk assessment
ConclusionsVisual inspection (and candling) of fishery products as required by EU legislation is not efficient for parasite detection. Consequently, visible (and non-visible) Anisakis reach the market and may be detected (and eaten) by consumers. Marine fish appears to be the only industrial food product that is at high risk of containing parasites when placed on the market.Anisakiasis and allergy to Anisakis are hidden, underestimated emerging zoonoses worldwide. There is a need to better understand the impact of these zoonoses on individual health and particularly exposed human populations, and to assess the risk posed b...
Source: Trends in Food Science and Technology - February 9, 2019 Category: Food Science Source Type: research
