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Neurological Involvement in Primary Systemic Vasculitis
Conclusion Neurological involvement is a common complication of PSV (Table 1), and neurologists play an important role in the identification and diagnosis of PSV patients with otherwise unexplained neurological symptoms as their chief complaint. This article summarizes the neurological manifestations of PSV and hopes to improve neuroscientists' understanding of this broad range of diseases. TABLE 1 Table 1. Common CNS and PNS involvements of primary systemic vasculitis. Author Contributions SZ conceived the article and wrote the manuscript. DY and GT reviewed and edited the manuscript. All authors ...
Source: Frontiers in Neurology - April 25, 2019 Category: Neurology Source Type: research

Systemic Lupus Erythematosus With Isolated Psychiatric Symptoms and Antinuclear Antibody Detection in the Cerebrospinal Fluid
Conclusion: Some patients with psychiatric syndromes and increased ANA titers may suffer from psychiatric variants of SLE, even if the American College of Rheumatology criteria for SLE are not met. Whether the psychiatric symptoms in our patient represent a prodromal stage with the later manifestation of full-blown SLE or a subtype of SLE with isolated CNS involvement remains unclear. Regardless, early diagnosis and initiation of immunosuppressive treatment are essential steps in preventing further disease progression and organ damage. Intrathecal ANAs with extractable nuclear antigen differentiation may be a more sensitiv...
Source: Frontiers in Psychiatry - April 24, 2019 Category: Psychiatry Source Type: research

Schwannomas of the sinonasal tract and anterior skull base: A systematic review of 94 cases.
CONCLUSION: ASB and sinonasal schwannomas are rare lesions and should be considered in the differential diagnosis of ASB masses involving the cribriform plate with sinonasal extension. Gross total resection of these lesions should be considered the goal of operative management. PMID: 24717879 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - January 1, 2014 Category: ENT & OMF Authors: Sunaryo PL, Svider PF, Husain Q, Choudhry OJ, Eloy JA, Liu JK Tags: Am J Rhinol Allergy Source Type: research

Neurological manifestations of influenza infection in adults and children: results of a national british surveillance study
Conclusion This paediatric and adult UK cohort identified a severity of influenza related neurological manifestation not reported previously. Cases were more common in children, particularly those with underlying neurological conditions. Encephalopathy syndromes such as ANE, AIEF, HSE and AHL were seen more frequently in children and were associated with a worse outcome. Acute movement disorders and Guillain–Barré syndrome were identified more commonly in adults. Influenza related encephalopathy may be more common in those with abnormal genetically determined host inflammatory responses, but the virus itself i...
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: Goenka, A., Michael, B., Ledger, E., Hart, I., Absoud, M., Chow, G., Lilleker, J., Lim, M., Lunn, M., Peake, D., Pysden, K., Roberts, M., Carrol, E., Avula, S., Solomon, T., Kneen, R. Tags: Immunology (including allergy), Meningitis, Infection (neurology), Radiology, Adult intensive care, Radiology (diagnostics) Association of British Neurologists (ABN) joint meeting with the Royal College of Physicians (RCP), London, 23-24 October 2013 Source Type: research

A fatal case of 'primary' headache
We describe a case of a 33 year old caucasian male with a subacute history of headaches presenting to the medical team with pyrexia, confusion and hallucinations. He subsequently became disorientated, agitated and initially needed sedation and ventilation after becoming acutely hypoxic with autonomic instability. He was subsequently found to have dense, pre–geniculate blindness and generalised arreflexia. Magnetic resonance imaging demonstrated normal brain parenchyma but diffuse nodular thickening and enhancement of the basal leptomeninges in the brain and throughout the entire spinal cord. Lumbar puncture revealed ...
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: Dayanandan, R., Bindman, D., Chhetri, S. K., Jacob, J., Mathur, S., Mills, R. J. Tags: Immunology (including allergy), HIV/AIDS, Meningitis, Headache (including migraine), Infection (neurology), Neurooncology, Pain (neurology), CNS cancer, Ophthalmology, Radiology, Surgical diagnostic tests, Radiology (diagnostics) Association of British Source Type: research