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Analysis of the Function of LncRNA- < em > MSTRG.16919.1 < /em > in BHV-1-Infected Bovine Kidney Subculture Cells by Transcriptome Sequencing
Viruses. 2022 Sep 22;14(10):2104. doi: 10.3390/v14102104.ABSTRACTInfection of cattle with bovine herpesvirus type 1 (BHV-1) can lead to upper respiratory tract disease, conjunctivitis, or genital disease and cause serious economic losses to the cattle industry worldwide. The role of long noncoding RNAs in BHV-1 infection is not well understood. To explore the role of lncRNA-MSTRG.16919.1 in bovine herpes virus type I (BHV-1) infected MDBK cells, the lncRNA-MSTRG.16919.1 gene was silenced and sequenced transcriptome and sequencing data were analyzed by Edge R software, Gene Ontology (GO), the Kyoto Encyclopedia of Genes and...
Source: Herpes - October 27, 2022 Category: Infectious Diseases Authors: Fan Zhang Kunsheng Jiang Yuchun Wang Jinzhu Ma Baifen Song Source Type: research

Viruses, Vol. 14, Pages 2104: Analysis of the Function of LncRNA-MSTRG.16919.1 in BHV-1-infected Bovine Kidney Subculture Cells by Transcriptome Sequencing
ifen Song Infection of cattle with bovine herpesvirus type 1 (BHV&amp;minus;1) can lead to upper respiratory tract disease, conjunctivitis, or genital disease and cause serious economic losses to the cattle industry worldwide. The role of long noncoding RNAs in BHV&amp;minus;1 infection is not well understood. To explore the role of lncRNA&amp;minus;MSTRG.16919.1 in bovine herpes virus type I (BHV&amp;minus;1) infected MDBK cells, the lncRNA&amp;minus;MSTRG.16919.1 gene was silenced and sequenced transcriptome and sequencing data were analyzed by Edge R software, Gene Ontology (GO), the Kyoto Encycl...
Source: Viruses - September 22, 2022 Category: Virology Authors: Fan Zhang Kunsheng Jiang Yuchun Wang Jinzhu Ma Baifen Song Tags: Article Source Type: research

Gene Therapy Leaves a Vicious Cycle
Reena Goswami1, Gayatri Subramanian2, Liliya Silayeva1, Isabelle Newkirk1, Deborah Doctor1, Karan Chawla2, Saurabh Chattopadhyay2, Dhyan Chandra3, Nageswararao Chilukuri1 and Venkaiah Betapudi1,4* 1Neuroscience Branch, Research Division, United States Army Medical Research Institute of Chemical Defense, Aberdeen, MD, United States 2Department of Medical Microbiology and Immunology, University of Toledo College of Medicine and Life Sciences, Toledo, OH, United States 3Roswell Park Comprehensive Cancer Center, Buffalo, NY, United States 4Department of Physiology and Biophysics, Case Western Reserve University, Clev...
Source: Frontiers in Oncology - April 23, 2019 Category: Cancer & Oncology Source Type: research

SOCS and Herpesviruses, With Emphasis on Cytomegalovirus Retinitis
Christine I. Alston1,2 and Richard D. Dix1,2* 1Department of Biology, Viral Immunology Center, Georgia State University, Atlanta, GA, United States 2Department of Ophthalmology, Emory University School of Medicine, Atlanta, GA, United States Suppressor of cytokine signaling (SOCS) proteins provide selective negative feedback to prevent pathogeneses caused by overstimulation of the immune system. Of the eight known SOCS proteins, SOCS1 and SOCS3 are the best studied, and systemic deletion of either gene causes early lethality in mice. Many viruses, including herpesviruses such as herpes simplex virus and cytomega...
Source: Frontiers in Immunology - April 10, 2019 Category: Allergy & Immunology Source Type: research