Filtered By:
Infectious Disease: Aspergillus

This page shows you your search results in order of relevance. This is page number 14.

Order by Relevance | Date

Total 481 results found since Jan 2013.

The importance of mold sensitivity in nonallergic rhinitis patients
ConclusionThis study suggests that LAR may exist in a significant number of the persistent rhinitis patients who were previously considered as NAR based on negative SPTs or serum sIgE tests. To the best of our knowledge, this is the first study evaluating a nasal local allergic response to both indoor and outdoor molds.
Source: International Forum of Allergy and Rhinology - February 16, 2016 Category: Allergy & Immunology Authors: Mustafa Demirtürk, Aslı Gelincik, Murat Ulusan, Belkıs Ertek, Suna Büyüköztürk, Bahattin Çolakoğlu Tags: ORIGINAL ARTICLE Source Type: research

Subchronic exposures to fungal bioaerosols promotes allergic pulmonary inflammation in naïve mice
Conclusions & Clinical RelevanceRepeated inhalation of fungal aerosols resulted in significant pulmonary pathology mediated by dynamic shifts in specific immune populations and their cytokines. These studies provide novel insights into the immunological mechanisms and targets that govern the health outcomes that result from repeated inhalation of fungal bioaerosols in contaminated environments.This article is protected by copyright. All rights reserved.
Source: Clinical and Experimental Allergy - February 1, 2016 Category: Allergy & Immunology Authors: Ajay P. Nayak, Brett J. Green, Angela R. Lemons, Nikki B. Marshall, W. Travis Goldsmith, Michael L. Kashon, Stacey E. Anderson, Dori R. Germolec, Donald H. Beezhold Tags: Original Article ‐Experimental Models of Allergic Disease Source Type: research

Comparison of Performance Characteristics of Aspergillus PCR in Testing a Range of Blood-Based Samples in Accordance with International Methodological Recommendations Mycology
This study confirms that Aspergillus PCR testing of plasma provides robust performance while utilizing commercial automated DNA extraction processes. Combining PCR testing of different blood fractions allows IA to be both confidently diagnosed and excluded. A requirement for multiple PCR-positive plasma samples provides similar diagnostic utility and is technically less demanding. Time to diagnosis may be enhanced by testing multiple contemporaneously obtained sample types.
Source: Journal of Clinical Microbiology - February 25, 2016 Category: Microbiology Authors: Springer, J., White, P. L., Hamilton, S., Michel, D., Barnes, R. A., Einsele, H., Löffler, J. Tags: Mycology Source Type: research

Characterization of Fungi Isolated from the Equipment Used in the International Space Station or Space Shuttle
Abstract As a part of a series of studies regarding the microbial biota in manned space environments, we isolated fungi from six pieces of equipment recovered from the Japanese Experimental Module “KIBO” of the International Space Station (ISS) and from a Space Shuttle. Thirty‐seven strains of fungi were isolated and identified, and were investigated with regard to morphological phenotypes and antifungal susceptibilities. The variety of fungi isolated in this study was similar to several previous reports. The dominant species belonged to the genera Penicillium, Aspergillus, and Cladosporium, which are potential causa...
Source: Microbiology and Immunology - February 1, 2016 Category: Microbiology Authors: Kazuo Satoh, Takashi Yamazaki, Takako Nakayama, Yoshiko Umeda, Mohamed Mahdi Alshahni, Miho Makimura, Koichi Makimura Tags: Original Article Source Type: research

Calcineurin inhibitors impair neutrophil activity against Aspergillus fumigatus in allogenic hematopoietic stem cell transplant recipients
In allogenic hematopoietic stem cell transplant recipients, fungal innate immunity driven by neutrophils is altered during the first months of the graft, in relation with the use of calcineurin inhibitors.
Source: Journal of Allergy and Clinical Immunology - April 5, 2016 Category: Allergy & Immunology Authors: Sébastien Imbert, Priscillia Bresler, Alexandre Boissonnas, Lauraine Gauthier, Laëtitia Souchet, Madalina Uzunov, Véronique Leblond, Dominique Mazier, Stéphanie Nguyen, Arnaud Fekkar Source Type: research

Basophil activation test determination of CD63 combined with CD203c is not superior to CD203c alone in identifying ABPA in cystic fibrosis
CD203c level at the surface of allergen-activated basophils is the best marker to identify allergic bronchopulmonary aspergillosis (ABPA) and discriminate from Aspergillus fumigatus colonization in patients with cystic fibrosis.
Source: Journal of Allergy and Clinical Immunology - April 20, 2016 Category: Allergy & Immunology Authors: Yael Gernez, Jeffrey Walters, Rabindra Tirouvanziam, Leonore A. Herzenberg, Richard B. Moss Source Type: research

Calcineurin inhibitors impair neutrophil activity against Aspergillus fumigatus in allogeneic hematopoietic stem cell transplant recipients
Neutrophils are key effectors against the widely distributed mold Aspergillus fumigatus, which is a major threat for immunocompromised patients, including allogeneic hematopoietic stem cell transplant (HSCT) recipients. Yet little is known about neutrophil activity over time after cell transplantation, especially regarding A fumigatus.
Source: Journal of Allergy and Clinical Immunology - April 5, 2016 Category: Allergy & Immunology Authors: Sébastien Imbert, Priscillia Bresler, Alexandre Boissonnas, Lauraine Gauthier, Laëtitia Souchet, Madalina Uzunov, Véronique Leblond, Dominique Mazier, Stéphanie Nguyen, Arnaud Fekkar Source Type: research

Evaluation of Malassezia and Common Fungal Pathogens in Subtypes of Chronic Rhinosinusitis
ConclusionThis study confirmed and speciated Malassezia in healthy and diseased sinuses. Presence of Malassezia species in all groups suggests a commensal role for the fungus. Future work will determine whether Malassezia influences CRS pathogenesis. Aspergillus species were identified in fungal CRS subtypes despite negative surgical cultures, highlighting the importance of culture‐independent technology.
Source: International Forum of Allergy and Rhinology - April 30, 2016 Category: Allergy & Immunology Authors: Jonathan T. Gelber, Emily K. Cope, Andrew N. Goldberg, Steven D. Pletcher Tags: ORIGINAL ARTICLE Source Type: research

Coexisting atopic conditions influence the likelihood of allergic bronchopulmonary aspergillosis in asthma
The diagnosis of allergic bronchopulmonary aspergillosis (ABPA) in asthma is often made in patients with total serum IgE levels greater than 1,000 IU/mL in conjunction with evidence of Aspergillus sensitization. The specificity of total serum IgE for the diagnosis of ABPA is low even when combined with serum Aspergillus specific IgE.
Source: Annals of Allergy, Asthma and Immunology - May 23, 2016 Category: Allergy & Immunology Authors: Tunn Ren Tay, Julian Bosco, Andrew Gillman, Heather Aumann, Robert Stirling, Robyn O'Hehir, Mark Hew Tags: Original Article Source Type: research

Beneficial effect of Lactococcus lactis NCC 2287 in a murine model of eosinophilic esophagitis
ConclusionWe identified a Lactococcus lactis strain, able to attenuate esophageal eosinophilic inflammation in a preclinical model of EoE. This effect is strain specific and depends on the timing and duration of bacterial supplementation. Confirmation of these observations in human clinical trials is warranted.This article is protected by copyright. All rights reserved.
Source: Allergy - June 3, 2016 Category: Allergy & Immunology Authors: Sébastien Holvoet, Rémi Doucet‐Ladevèze, Marie Perrot, Caroline Barretto, Sophie Nutten, Carine Blanchard Tags: Original Article: Gastrointestinal Diseases Source Type: research

Clinical studies of allergic diseases. IV. Bronchial asthma due to hypersensitivity to mold spores
1. Criteria were formulated which should be fulfilled when specific hypersensitivity toward mould spores should be recognised. 2. A method for manufacturing an extract purely from spores and for testing this extract was described. 3. Several cases of a nearly strictly monovalent (single fungus) allergy to mould spores were described and the course of the analysis of these illnesses was dealt with.
Source: The Aspergillus Website - updates - June 6, 2016 Category: Respiratory Medicine Authors: HLeSueur Source Type: news

An evaluation of invasive fungal sinusitis outcomes with subsite analysis and use of frozen section analysis
ConclusionOverall survival for IFS remains poor. Widespread disease and nasal septum involvement were associated with a negative clinical course. Early identification and aggressive surgical and antifungal therapy is warranted. Even despite intense therapy, comorbid conditions and drug toxicity increase mortality and complicate the clinical course.
Source: International Forum of Allergy and Rhinology - April 30, 2016 Category: Allergy & Immunology Authors: James Foshee, Chris Luminais, James Casey, Alexander Farag, Anthony Prestipino, Alfred Marc Iloreta, Gurston Nyquist, Marc Rosen Tags: ORIGINAL ARTICLE Source Type: research

Immunoproteomics of Aspergillus for the development of biomarkers and immunotherapies
This article is protected by copyright. All rights reserved
Source: Proteomics. Clinical Applications - June 16, 2016 Category: Biochemistry Authors: Olaf Kniemeyer, Frank Ebel, Thomas Krüger, Petra Bacher, Alexander Scheffold, Ting Luo, Maria Strassburger, Axel A. Brakhage Tags: Review Source Type: research

Basophil activation test determination of CD63 combined with CD203c is not superior to CD203c alone in identifying allergic bronchopulmonary aspergillosis in cystic fibrosis
We would like to comment on the letter from Chirumbolo1 regarding the work of our collaborators Mirkovic et  al.2 Mirkovic et al demonstrated that Aspergillus fumigatus–sensitized individuals display an increased upregulation of the surface-expressed basophil marker CD203c in response to ex vivo challenge with A fumigatus extract, a response readily measurable by flow cytometry in the basophil activa tion test (BAT). However, Mirkovic et al did not report on evaluation of basophil CD63 expression, which is also upregulatd by allergen challenge, as shown in our previous published work.
Source: Journal of Allergy and Clinical Immunology - April 20, 2016 Category: Allergy & Immunology Authors: Yael Gernez, Jeffrey Waters, Rabindra Tirouvanziam, Leonore Herzenberg, Richard Moss Tags: Letter to the Editor Source Type: research

Calcineurin inhibitors impair neutrophil activity against Aspergillus fumigatus in allogeneic hematopoietic stem cell transplant recipients
Neutrophils are key effectors against the widely distributed mold Aspergillus fumigatus, which is a major threat for immunocompromised patients, including allogeneic hematopoietic stem cell transplant (HSCT) recipients. Yet little is known about neutrophil activity over time after cell transplantation, especially regarding A fumigatus.
Source: Journal of Allergy and Clinical Immunology - April 5, 2016 Category: Allergy & Immunology Authors: S ébastien Imbert, Priscillia Bresler, Alexandre Boissonnas, Lauraine Gauthier, Laëtitia Souchet, Madalina Uzunov, Véronique Leblond, Dominique Mazier, Stéphanie Nguyen, Arnaud Fekkar Source Type: research