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Utility of minor determinants for skin testing in inpatient penicillin allergy evaluation.
CONCLUSION: This study found a high rate of exclusively positive skin test reactions to the minor determinants penicilloate and penilloate. Because patients with positive test reactions are at increased risk of reaction to drug challenge, these data support the use of these reagents for penicillin skin testing in hospitalized patients.
PMID: 28743423 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - July 22, 2017 Category: Allergy & Immunology Authors: Geng B, Eastman JJ, Mori K, Braskett M, Riedl MA Tags: Ann Allergy Asthma Immunol Source Type: research
Altered miR ‐193a‐5p expression in children with cow's milk allergy
ConclusionsOur results suggest that miR‐193a‐5p is a post‐transcriptional regulator of IL‐4 expression and could have a role in IgE‐mediated CMA. This miRNA could be a novel diagnostic and therapeutic target for this common form of food allergy in childhood.This article is protected by copyright. All rights reserved.
Source: Allergy - August 30, 2017 Category: Allergy & Immunology Authors: Valeria D'Argenio, Valentina Del Monaco, Lorella Paparo, Fatima Domenica Elisa De Palma, Rita Nocerino, Francesca D'Alessio, Feliciano Visconte, Valentina Discepolo, Luigi Del Vecchio, Francesco Salvatore, Roberto Berni Canani Tags: Original Article: Experimental Allergy and Immunology Source Type: research
Allergen specificity of early peanut consumption and effect on development of allergic disease in the Learning Early About Peanut Allergy study cohort
Early introduction of dietary peanut in high-risk infants with severe eczema, egg allergy, or both prevented peanut allergy at 5 years of age in the Learning Early About Peanut Allergy (LEAP) study. The protective effect persisted after 12 months of avoiding peanuts in the 12-month extension of the LEAP study (LEAP-On). It is unclear whether this benefit is allergen and allergic disease specific.
Source: Journal of Allergy and Clinical Immunology - October 30, 2017 Category: Allergy & Immunology Authors: George du Toit, Peter H. Sayre, Graham Roberts, Kaitie Lawson, Michelle L. Sever, Henry T. Bahnson, Helen R. Fisher, Mary Feeney, Suzana Radulovic, Monica Basting, Marshall Plaut, Gideon Lack, Immune Tolerance Network Learning Early About Peanut Allergy s Source Type: research
Galactose- α-1,3-galactose allergy: a rare syndrome and an atypical presentation.
In this study, we report the case of a 76-year-old male with an immediate reaction following the ingestion of red meat. Rigorous diagnostic exams, including prick test, prick-to-prick tests, serum specific IgE and SDS-PAGE IgE-immunoblotting, were performed. The α-gal epitope IgE re-turned a value of 35.3 kUA/L, leading the authors to believe that this is an atypical case of α-gal allergy.
PMID: 29479927 [PubMed - as supplied by publisher]
Source: European Annals of Allergy and Clinical Immunology - February 27, 2018 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research
Allergy to LTP: to eat or not to eat sensitizing foods? A follow-up study.
Conclusions.Rosaceae / Prunoideae, nuts and peanut are the most frequent cause of new food allergies in the long term. Their exclusion from patient's diets at baseline should be considered on an individual basis.
PMID: 29542889 [PubMed - as supplied by publisher]
Source: European Annals of Allergy and Clinical Immunology - March 16, 2018 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research
Mycoplasma pneumoniae induces allergy by producing p1-specific IgE.
CONCLUSION: MP is not only an infectious agent but also an allergen for certain individuals. The P1 protein of MP can induce the production of P1-specific IgE.
PMID: 29555351 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - March 16, 2018 Category: Allergy & Immunology Authors: Ye Q, Mao JH, Shu Q, Shang SQ Tags: Ann Allergy Asthma Immunol Source Type: research
Allergen-Specific Immunotherapies for Food Allergy.
Authors: Feuille E, Nowak-Wegrzyn A
Abstract
With rising prevalence of food allergy (FA), allergen-specific immunotherapy (AIT) for FA has become an active area of research in recent years. In AIT, incrementally increasing doses of inciting allergen are given with the goal to increase tolerance, initially through desensitization, which relies on regular exposure to allergen. With prolonged therapy in some subjects, AIT may induce sustained unresponsiveness, in which tolerance is retained after a period of allergen avoidance. Methods of AIT currently under study in humans include oral, sublingual, epicutaneous, and ...
Source: Allergy, Asthma and Immunology Research - April 22, 2018 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research
Chinese Society of Allergy Guidelines for Diagnosis and Treatment of Allergic Rhinitis.
Authors: Cheng L, Chen J, Fu Q, He S, Li H, Liu Z, Tan G, Tao Z, Wang D, Wen W, Xu R, Xu Y, Yang Q, Zhang C, Zhang G, Zhang R, Zhang Y, Zhou B, Zhu D, Chen L, Cui X, Deng Y, Guo Z, Huang Z, Huang Z, Li H, Li J, Li W, Li Y, Xi L, Lou H, Lu M, Ouyang Y, Shi W, Tao X, Tian H, Wang C, Wang M, Wang N, Wang X, Xie H, Yu S, Zhao R, Zheng M, Zhou H, Zhu L, Zhang L
Abstract
Allergic rhinitis (AR) is a global health problem that causes major illnesses and disabilities worldwide. Epidemiologic studies have demonstrated that the prevalence of AR has increased progressively over the last few decades in more developed countries ...
Source: Allergy, Asthma and Immunology Research - June 28, 2018 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research
Allergy in adolescent population (14-18 years) living in Campania region (Southern Italy). A multicenter study.
In conclusion, our findings confirm the high prevalence and clinical significance of airway allergic sensitization in the adolescents living in Campania region.
PMID: 30066997 [PubMed - as supplied by publisher]
Source: European Annals of Allergy and Clinical Immunology - August 6, 2018 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research
Migrants and allergy: a new view of the atopic march.
Authors: Biagioni B, Vitiello G, Bormioli S, Tarrini D, Lombardi C, Rossi O, Parronchi P
Abstract
Summary: Atopy is the result of the influence of environmental factors on genetically predisposed individuals. Migration flows represent an interesting model to study the possible reciprocal roles of genes and environment. In this review the following issues influencing the development of allergic sensitization and/or atopic disorders in migrants will be rooted out: 1) ethnicity, genetic polymorphisms and risk of atopy; 2) double faceted effects of parasitic infestations; 3) biodiversity loss and industrial progress. M...
Source: European Annals of Allergy and Clinical Immunology - April 16, 2019 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research
Association of Staphylococcus aureus colonization with food allergy occurs independently of eczema severity
Staphylococcus aureus has been implicated in the pathophysiology of eczema, allergic rhinitis, asthma, and food allergy. S aureus is a marker of more severe eczema, which is a risk factor for food sensitization/allergy. Therefore it might be that the association between S aureus and food allergy in eczematous patients is related to eczema severity.
Source: Journal of Allergy and Clinical Immunology - May 30, 2019 Category: Allergy & Immunology Authors: Olympia Tsilochristou, George du Toit, Peter H. Sayre, Graham Roberts, Kaitie Lawson, Michelle L. Sever, Henry T. Bahnson, Suzana Radulovic, Monica Basting, Marshall Plaut, Gideon Lack, Immune Tolerance Network Learning Early About Peanut Allergy Study Te Source Type: research
Allergy immunotherapies for allergic rhinitis: systematic review and assessment of evolving quality.
Conclusions. When as-sessing grass AIT, it is important to focus not only on endpoints but also on the quality of evidence.
PMID: 31187972 [PubMed - as supplied by publisher]
Source: European Annals of Allergy and Clinical Immunology - June 14, 2019 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research
Use of a comprehensive diagnostic algorithm for anisakis allergy in a high seropreva-lence Mediterranean setting.
Conclusions. Our preliminary findings support the high clinical specificity of BAT for AA diagnosis, suggesting implementing this method in a comprehensive diagnostic algorithm.
PMID: 31668056 [PubMed - as supplied by publisher]
Source: European Annals of Allergy and Clinical Immunology - November 2, 2019 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research
P100 scit in an academic allergy center: a retrospective review
In this study, details of SCIT use at an academic-based allergy clinic is reported after implementation of a new SCIT electronic medical record (EMR).
Source: Annals of Allergy, Asthma and Immunology - October 31, 2019 Category: Allergy & Immunology Authors: M. Tankersley, H. Russell Tags: Allergy Diagnostics and Immunotherapy Source Type: research
Blood or skin: what is best in predicting cow's milk allergy diagnosis?
This study is a retrospective analysis of consecutive children (0-18 years-old) with suspected CMA tested with SPT and sIgE for cow's milk (CM) and its fractions between 2016-2017. CMA diagnosis was defined by a positive oral food challenge or a highly suggestive clinical history of CMA and SPT and/or sIgE positive to CM and/or its fractions. One hundred and five patients were included, 58% males with a median age of 2.5 (P25-P75:1-6) years and the diagnosis was confirmed in 83 patients (79%). The variables associated with CMA diagnosis were SPT with CM (p minor 0,05) and casein (p minor 0,05) and all sIgE to CM and its fr...
Source: European Annals of Allergy and Clinical Immunology - December 5, 2019 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research
