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Total 303 results found since Jan 2013.

Early-Life Nutrition and Gut Immune Development.
Authors: van den Elsen LWJ, Rekima A, Verhasselt V Abstract Gut immune function conditions the development of local and systemic diseases that result from defects in immune regulation, such as inflammatory bowel disease, allergy and obesity. As epidemiological studies support the developmental origin of health and disease, deciphering the critical factors modulating gut immune development should allow the advance of primary prevention strategies specifically adapted to the early-life immune system. Here, we will review gut mucosal immunity development and cover in more detail the recent understanding of the impact ...
Source: Nestlee Nutrition Institute Workshop Series - March 15, 2019 Category: Nutrition Tags: Nestle Nutr Inst Workshop Ser Source Type: research

News & Notes
Registration is open for the 2019 AAAAI Practice Management Workshop, July 12-14 in Cincinnati, Ohio. Visit education.aaaai.org/19PMW to register and book your hotel room.
Source: Journal of Allergy and Clinical Immunology - March 31, 2019 Category: Allergy & Immunology Tags: Reader service Source Type: research

Developing an Intervention to Improve the Health Related Quality of Life in Children and Young People With Serious Parental Mental Illness
Conclusion: Young SMILES captures a broad age range and level of need for CAPRI and can be evaluated with quantifiable child-centered outcomes. In line with current policy directives, this is the first UK-based, multi-context intervention to improve QoL in this population. Implementation and referral mechanisms are currently being evaluated in a multi-site feasibility trial. Introduction Children and adolescents living with parental mental illness (CAPRI) are poorly provided for in current social care and educational settings (1, 2). Children and young people (CYP) growing up in families affected by parental mental h...
Source: Frontiers in Psychiatry - April 8, 2019 Category: Psychiatry Source Type: research

Use of Growth Factors and Cytokines to Treat Injuries Resulting from a Radiation Public Health Emergency.
Abstract In response to concerns over possible radiological or nuclear incidents, the Radiation and Nuclear Countermeasures Program within the National Institute of Allergy and Infectious Diseases (NIAID) was tasked by the U.S. Department of Health and Human Services to support development of medical countermeasures (MCM) to treat the acute and delayed injuries that can result from radiation exposure. To date, the only three drugs approved by the U.S. Food and Drug Administration for treatment of acute radiation syndrome are growth factors targeting granulocyte (Neupogen® or Neulasta®) or granulocyte and macroph...
Source: Radiation Research - May 6, 2019 Category: Physics Authors: Horta ZP, Case CM, DiCarlo AL Tags: Radiat Res Source Type: research

Use of Growth Factors and Other Cytokines for Treatment of Injuries During a Radiation Public Health Emergency.
This report reviews the information presented, and provides an overview of the discussions from a guided breakout session. PMID: 31081742 [PubMed - as supplied by publisher]
Source: Radiation Research - May 12, 2019 Category: Physics Authors: DiCarlo AL, Horta ZP, Aldrich JT, Jakubowski AA, Skinner WK, Case CM Tags: Radiat Res Source Type: research

News & Notes
The AAAAI Practice Management Workshop can change your career in one weekend —just ask Julie A. Wendt, MD, PhD, FAAAAI.
Source: Journal of Allergy and Clinical Immunology - May 31, 2019 Category: Allergy & Immunology Tags: Reader service Source Type: research

Abstracts of 11th C1-inhibitor Deficiency & Angioedema Workshop
Source: Allergy, Asthma and Clinical Immunology - August 13, 2019 Category: Allergy & Immunology Tags: Meeting Abstracts Source Type: research

The Immune Epitope Database and Analysis Resource Program 2003 –2018: reflections and outlook
AbstractThe Immune Epitope Database and Analysis Resource (IEDB) contains information related to antibodies and T cells across an expansive scope of research fields (infectious diseases, allergy, autoimmunity, and transplantation). Capture and representation of the data to reflect growing scientific standards and techniques have required continual refinement of our rigorous curation and query and reporting processes beginning with the automated classification of over 28 million PubMed abstracts, and resulting in easily searchable data from over 20,000 published manuscripts. Data related to MHC binding and elution, nonpepti...
Source: Immunogenetics - November 24, 2019 Category: Genetics & Stem Cells Source Type: research

Immunological mechanisms of inducing HIV immunity in infants.
Abstract The potential advantages and unique challenges of the early life immune system for the development of HIV-specific broadly neutralizing antibodies were discussed during a workshop entitled "Immunological Mechanisms of Inducing HIV Immunity in Infants" sponsored by the National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH) in conjunction with the 2018 HIVR4P Conference held in Madrid, Spain. A safe and effective HIV vaccine remains a critical need in the fight against the HIV pandemic, especially to prevent emerging infections in infants, adolescents, and young a...
Source: Vaccine - November 20, 2019 Category: Allergy & Immunology Authors: Fouda GG, De Paris K, Levy O, Marchant A, Gray G, Permar S, Marovich M, Singh A Tags: Vaccine Source Type: research

Engineering immunity for next generation HIV vaccines: The intersection of bioengineering and immunology.
Abstract Bioengineering approaches grounded in immunology have the potential for the discovery and development of a successful HIV vaccine. The overarching goal is to engineer immunity through a fusion of immunology with bioengineering to create novel strategies for the design, development and delivery of vaccines based on the controlled modulation of the immune system. To foster these collaborations, the National Institute of Allergy and Infectious Diseases (NIAID) and National Institute of Biomedical Imaging and Bioengineering (NIBIB) brought together a group of experts (see Table 1) from these diverse fields fo...
Source: Vaccine - November 19, 2019 Category: Allergy & Immunology Authors: D'Souza MP, Rele S, Haynes BF, Hu DJ, Kaplan DL, Mamaghani S, Rampulla D Tags: Vaccine Source Type: research

How can we minimise the use of regular oral corticosteroids in asthma?
Options to achieve oral corticosteroid (OCS)-sparing have been triggering increasing interest since the 1970s because of the side-effects of OCSs, and this has now become achievable with biologics. The Société de Pneumologie de Langue Francaise workshop on OCSs aimed to conduct a comprehensive review of the basics for OCS use in asthma and issue key research questions. Pharmacology and definition of regular use were reviewed by the first working group (WG1). WG2 examined whether regular OCS use is associated with T2 endotype. WG3 reported on the specificities of the paediatric area. Key "research statement pr...
Source: European Respiratory Review - February 4, 2020 Category: Respiratory Medicine Authors: Bourdin, A., Adcock, I., Berger, P., Bonniaud, P., Chanson, P., Chenivesse, C., de Blic, J., Deschildre, A., Devilliers, P., Devouassoux, G., Didier, A., Garcia, G., Magnan, A., Martinat, Y., Perez, T., Roche, N., Taille, C., Val, P., Chanez, P. Tags: Asthma and allergy Review Source Type: research

Immunomodulatory Components of Human Colostrum and Milk.
Authors: Tlaskalová-Hogenová H, Kverka M, Hrdý J Abstract Human milk is a unique and complex secretion differing from lacteal secretions of other species. Besides nutrition, it provides protection during the newborn's adaption to the extrauterine environment and reduces the morbidity and mortality caused by both infectious and noninfectious diseases. Its components act directly against infectious agents, but they also accelerate the newborn's immune system development, increasing its capacity for defense and reducing the risk of allergy and other immune-related diseases. Cytokines show the most refined immunomod...
Source: Nestlee Nutrition Institute Workshop Series - March 18, 2020 Category: Nutrition Tags: Nestle Nutr Inst Workshop Ser Source Type: research

Breastfeeding, a Personalized Medicine with Influence on Short- and Long-Term Immune Health.
Authors: Verhasselt V Abstract The neonatal immune system has its own reactivity, constraints, and challenges, which profoundly differ from the adult. Breast milk is most probably a key requirement both for optimal immune function in early life and for imprinting of the immune system for long-term immune health. Here, we will highlight how breast milk fills the needs and the gaps of the developing immune system and thereby represents the unbeatable way to prevent infectious disease. We will further focus on some factors in breast milk that we extensively studied and found to actively influence the immune trajectory...
Source: Nestlee Nutrition Institute Workshop Series - March 31, 2020 Category: Nutrition Tags: Nestle Nutr Inst Workshop Ser Source Type: research

News and Notes
Get important practice updates for 2020 from leading experts at the 2020 AAAAI Practice Management Workshop, July 17-19 in Washington, DC.
Source: Journal of Allergy and Clinical Immunology - March 31, 2020 Category: Allergy & Immunology Tags: Reader service Source Type: research

‘This Is Really Life or Death.’ For People With Disabilities, Coronavirus Is Making It Harder Than Ever to Receive Care
Jeiri Flores is normally a busy, upbeat 29-year-old. But amid the COVID-19 pandemic, her go-to thought has been dark. “If I get this,” she thinks, “I’m gonna die.” This is not an unfounded fear. Flores has cerebral palsy, uses a wheelchair and needs assistance with everyday tasks, including making food and getting dressed. Her disability means it’s tougher for her immune system to kick illnesses; she’s still recovering from a bout of pneumonia she had in January. So beating COVID-19 could easily mean a protracted battle and months in a hospital—a prospect that comes with a c...
Source: TIME: Health - April 24, 2020 Category: Consumer Health News Authors: Abigail Abrams Tags: Uncategorized COVID-19 Source Type: news