Filtered By:
Drug: Insulin

This page shows you your search results in order of relevance.

Order by Relevance | Date

Total 338 results found since Jan 2013.

Successful Treatment of Insulin Allergy with Desensitization Therapy: A Case Report and Literature Review.
Abstract Insulin therapy is an essential treatment for type 1 and uncontrolled type 2 diabetes mellitus (DM). Hypersensitivity reactions have been described since the first administration of insulin, the same as any other therapy. Despite being a rare situation nowadays, it requires careful intra-hospital monitoring and multidisciplinary management. Here, we present a case of a 57-year-old patient with type 2 DM, an average glycemic control, and both penicillin and insulin allergy. Heunderwent a desensitization protocol which allowed successfully dismiss him with intermediate-acting insulin. PMID: 32245301 [P...
Source: Iranian Journal of Allergy, Asthma and Immunology - October 22, 2019 Category: Allergy & Immunology Authors: Elfekih H, Hadjkacem F, Elleuch M, Ghorbel D, Charfi N, Mnif F, Rekik N, Mnif M, Abid M Tags: Iran J Allergy Asthma Immunol Source Type: research

Insulin-like growth factor 2 enhances regulatory T-cell functions and suppresses food allergy in an experimental model
Conclusions: Activation of IGF2R enhances Treg cell functions in suppressing other Teff cell activities and inhibiting allergic inflammation in the intestine.
Source: Journal of Allergy and Clinical Immunology - April 3, 2014 Category: Allergy & Immunology Authors: Gui Yang, Xiao-Rui Geng, Jiang-Ping Song, Yingying Wu, Hao Yan, Zhengke Zhan, Litao Yang, Weiyi He, Zhi-Qiang Liu, Shuqi Qiu, Zhigang Liu, Ping-Chang Yang Tags: Mechanisms of allergy and clinical immunology Source Type: research

Insulin allergy can be successfully managed by a systematic approach
ConclusionInsulin allergy can be managed by a systematic approach, and symptom relief is obtainable in most patients.
Source: Clinical and Translational Allergy - September 25, 2018 Category: Allergy & Immunology Source Type: research

Highlights in allergic contact dermatitis 2018/2019
Purpose of review The purpose was to highlight recent findings especially concerning new and old allergens, trends, diagnosis and causes of contact allergy. Recent findings Nickel is still the most frequent cause of contact allergy in women and piercings remain an important risk factor. Countries with a long history of regulation of contact allergens have the lowest level of contact allergy to nickel and chromium in Europe. Among the most frequent causes of fragrance contact allergy is terpenes, which are oxidized such as limonene, linalool and in some countries: geraniol. Methylisothiazolinone is still causing consid...
Source: Current Opinion in Allergy and Clinical Immunology - June 27, 2019 Category: Allergy & Immunology Tags: SKIN ALLERGY: Edited by Thomas Werfel and Torsten Zuberbier Source Type: research

The allergy to insulin about a case treated by montelukast
The insulin allergy is IgE and is manifested by cutaneous form of local reactions erythema and swelling at the injection or generalized urticarial site. Flare reactions appear in the ancient sites of insulin injection. There may be itching to planto palmar and hot generalized heat.More serious accidents with angioedema anaphylaxis and with hypotension dyspnea resulting death are not uncommon.An 18 Years diabetes patient insulin-dependent since 6 Years. He has been for one year repeated episodes of edema with Quick asphyxia and hypotension. Occurred to after the injection of insulin became pruriginous. Spaced and serious cr...
Source: European Respiratory Journal - December 23, 2014 Category: Respiratory Medicine Authors: Bali, F. Tags: 5.3 Allergy and Immunology Source Type: research

The Effects of Liraglutide on Insulin Allergy in T2DM The Effects of Liraglutide on Insulin Allergy in T2DM
This case suggests that the GLP-1 analog liraglutide might be a useful alternative for treatment of insulin allergy and anti-insulin antibodies in patients with type 2 diabetes.Journal of Medical Case Reports
Source: Medscape Allergy Headlines - August 25, 2016 Category: Allergy & Immunology Tags: Diabetes & Endocrinology Journal Article Source Type: news

M008 insulin allergy in a patient with type 1 diabetes mellitus
Rates of insulin allergy have significantly decreased as human insulin has become commercially available and replaced animal derived products. While rare, insulin allergy may present as Gel-Coombs type I, III or IV hypersensitivity reactions and management can be particularly complex in patients with type 1 diabetes mellitus.
Source: Annals of Allergy, Asthma and Immunology - November 1, 2020 Category: Allergy & Immunology Authors: A. Alvarez, J. Chambliss Source Type: research

Ovalbumin induced allergic rhinitis and development of prediabetes condition to rats: possible role of Th2 cytokines.
Abstract Th1 and Th2 paradigm suggests inverse relation between both types of cytokines and the underlying pathological conditions. In contrast to this, we have reported the development of diabetes mellitus (DM) in Parthenium hysterophorous induced allergic rhinitis (AR) to rats. In silico interactome study also revealed interaction between Th2 and Th1 cytokines and associated pathways involved in DM. Therefore, in the present study we tried to understand the changes in glucose homeostasis and metabolic parameters on the background of ovalbumin (OVA) induced allergic rhinitis (AR) to rats. Three groups of seven ra...
Source: Inflammation and Allergy Drug Targets - March 8, 2013 Category: Allergy & Immunology Authors: Juneja L, Parmar HS Tags: Inflamm Allergy Drug Targets Source Type: research

Insulin-like growth factor 2 enhances regulatory T-cell functions and suppresses food allergy in an experimental model
Source: Journal of Allergy and Clinical Immunology - April 1, 2014 Category: Allergy & Immunology Authors: Gui Yang, Xiao-Rui Geng, Jiang-Ping Song, Yingying Wu, Hao Yan, Zhengke Zhan, Litao Yang, Weiyi He, Zhi-Qiang Liu, Shuqi Qiu, Zhigang Liu, Ping-Chang Yang Tags: Mechanisms of allergy and clinical immunology Source Type: research

Novel immunotherapy approaches to food allergy
Purpose of reviewDespite reaching high percentages of desensitization using allergen-specific immunotherapy (SIT) in patients with food allergy, recent studies suggest only a low number of patients to reach persistent clinical tolerance. This review describes current developments in strategies to improve safety and long-term efficacy of SIT. Recent findingsModified allergens or tolerogenic peptides, ultimately optimized for human leukocyte antigen background of the patient, are explored for tolerance induction, whereas anti-IgE antibody (Omalizumab) may be used to facilitate SIT safety. Adjunct therapies to enhance efficac...
Source: Current Opinion in Allergy and Clinical Immunology - October 24, 2014 Category: Allergy & Immunology Tags: IMMUNOTHERAPY AND NEW TREATMENTS: Edited by Giovanni Passalacqua and Robert Bush Source Type: research

Angiogenesis as a therapeutic target for obesity and metabolic diseases.
Authors: Cao Y Abstract White adipose tissue constantly experiences expansion and shrinkage during the entire adulthood, depending on the metabolic status of the host. Emerging evidence demonstrates that the plasticity of white adipose tissue is tightly controlled by the adipose vasculature, which may grow or regress to coordinate adipose tissue metabolism. In metabolically active brown adipose tissue, an exceedingly high density of blood vessels may perfuse oxygen for energy consumption. Consequently, modulation of vascular density and functions in both white adipose tissue and brown adipose tissue may offer an ex...
Source: Chemical Immunology and Allergy - December 2, 2014 Category: Allergy & Immunology Tags: Chem Immunol Allergy Source Type: research

The Association Between The Chronic Use Of Non-Steroidal Anti-Inflammatory Drugs And Oxidative And Inflammatory Markers In The Elderly.
Conclusion: This study suggests that there is no association between the chronic or occasional use of NSAIDs and oxidative and inflammatory markers. It is known that NSAIDs have innumerable adverse effects, but they can have some benefits. So, additional studies are needed to clarify whether NSAIDs are associated with these markers and whether they are related what are their real consequences. PMID: 25544020 [PubMed - as supplied by publisher]
Source: Inflammation and Allergy Drug Targets - December 28, 2014 Category: Allergy & Immunology Authors: Ely LS, Valle Gottlieb MG, Engroff P, Gomes I, Moresco RN, Tatsch E, Bochi GV, Morrone FB, De Carli GA Tags: Inflamm Allergy Drug Targets Source Type: research

Desensitization to mecasermin in an insulin-like growth factor 1-deficient patient.
PMID: 25843163 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - April 2, 2015 Category: Allergy & Immunology Authors: Gutiérrez-Fernández D, Moreno-Ancillo Á, Foncubierta-Fernández A, López-Martínez I, Lechuga-Sancho A, Fernández-Anguita MJ Tags: Ann Allergy Asthma Immunol Source Type: research