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Drug: Dexamethasone
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Total 367 results found since Jan 2013.
Magnesium isoglycyrrhizinate alleviate airway inflammatory responses in ovalbumin-induced mouse model of allergic asthma
CONCLUSION: Our study findings support that nebulizer inhalation of MgIG as an effective therapy in treating the allergy induced asthma.PMID:35315307 | DOI:10.1080/08923973.2022.2055567
Source: Immunopharmacology and Immunotoxicology - March 22, 2022 Category: Allergy & Immunology Authors: Ye Yang Lei Huang Chongchong Tian Bingjun Qian Source Type: research
Design and optimization of ROS-reactive nanocarriers for controlled release of dexamethasone and real-time inhibition of mast cell activation
Upon activation, mast cells release many mediators, including reactive oxygen species (ROS) and tumor necrosis factor (TNF) orchestrating allergic inflammation. Nanocarriers (NCs) that can detect mast cell activation and respond by releasing anti-inflammatory compounds in real-time, would and effective therapy.
Source: Journal of Allergy and Clinical Immunology - February 1, 2022 Category: Allergy & Immunology Authors: Marianna Kulka, Ashley Wagner, Shammy Raj, Larry Unsworth Source Type: research
IRL201104, A Novel Immunomodulatory Peptide, Have A Comparable Effect To Dexamethasone In The Inflammation Associated To A Murine Model Of ARDS
Respiratory failure from Acute Respiratory Distress Syndrome or ARDS is a leading cause of mortality in patients with respiratory infections. Early administration of dexamethasone has shown to reduce mortality in patients with moderate-to-severe ARDS associated to infectious diseases, such us COVID-19. Our aim was to compare IRL201104 with dexamethasone in a classical model of ARDS to explore its potential in the treatment of this patient population.
Source: Journal of Allergy and Clinical Immunology - February 1, 2022 Category: Allergy & Immunology Authors: Jorge De Alba, Clare Burgess, Roly Foulkes Source Type: research
Abatacept (Cytotoxic T Lymphocyte Antigen 4-Fragment Crystallizable) Reduces Allergic Inflammation of Ovalbumin-Sensitized Mice
CONCLUSIONS: Aba suppresses allergic inflammation and appears to be a good treatment for AR.PMID:34994213 | DOI:10.1177/19458924211072364
Source: American Journal of Rhinology and Allergy - January 7, 2022 Category: ENT & OMF Authors: Jaein Chung Mi-Ra Choi Min Gyu Kim Soo Kyoung Park Yong Min Kim Source Type: research
Late Breaking Abstract - Steroid resistance in obese asthmatic patients: a potential role of obesity-related systemic oxidative stress
Conclusions: Systemic oxidative stress caused by enlarged adipose tissue might involve steroid resistance in obese asthmatic patients.
Source: European Respiratory Journal - November 25, 2021 Category: Respiratory Medicine Authors: To, M., Honda, N., Kano, I., Haruki, K., To, Y. Tags: Allergy and immunology Source Type: research
Evaluation of Asthma control and oral corticosteroids in Severe Asthma
Conclusions: Despite high-dose inhalation therapy plus additional controllers or OCS, only 34% of patients affected by SA had controlled asthma. Moreover, 31% of subjects daily took OCS. Of note, uncontrolled patients had a high eosinophilia and few were properly treated with biologics.
Source: European Respiratory Journal - November 25, 2021 Category: Respiratory Medicine Authors: Micheletto, C., Bilo, M. B., Antonicelli, L., De Michele, F., Musarra, A., Vagni, A. Tags: Airway pharmacology and treatment Source Type: research
Adrenal Sampling in Hyperaldosteronism With Contrast Allergy Adrenal Sampling in Hyperaldosteronism With Contrast Allergy
A patient with primary hyperaldosteronism and a severe allergy to contrast media was able to successfully undergo adrenal vein sampling using dexamethasone as premedication.Journal of the Endocrine Society
Source: Medscape Today Headlines - October 19, 2021 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news
Salidroside Mitigates Airway Inflammation in Asthmatic Mice via the AMPK/Akt/GSK3 β Signaling Pathway
Conclusion: SAL can inhibit bronchial hyperresponsiveness and reduce tracheal inflammation by increasing AMPK phosphorylation and inhibiting Akt and GSK3 β signaling pathways.Int Arch Allergy Immunol
Source: International Archives of Allergy and Immunology - October 11, 2021 Category: Allergy & Immunology Source Type: research
Meta-analysis of risk factors associated with oxaliplatin hypersensitivity reactions in cancer patients
This study aimed to investigate risk factors associated with oxaliplatin hypersensitivity reactions in cancer patients through a meta-analysis. A comprehensive retrieve of Chinese databases China National Knowledge Infrastructure, Wanfang Data, VIP Database and English databases PubMed, ScienceDirect, Embase and Cochrane library was conducted. The studies that meet the requirements for meta-analysis according to inclusion and exclusion criteria were screened and assessed for eligibility. Odds ratio (OR) / Weighted mean difference (WMD) and 95% confidence intervals (95% CIs) or calculable dichotomous and continuous raw data...
Source: International Journal of Clinical Oncology - October 9, 2021 Category: Cancer & Oncology Source Type: research
