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Drug: Tetracycline

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Total 6458 results found since Jan 2013.

Drug Resistance Characteristics and Macrolide-Resistant Mechanisms of Streptococcus pneumoniae in Wenzhou City, China.
CONCLUSIONS SP shows significant multi-drug resistance in Wenzhou City, whereas there is no clinical value of macrolides antibiotics for SP. cMLSB mediated by erm B gene is the most predominant phenotype among macrolide-resistant SP. The int Tn gene may play an important role in horizontal transfer and clonal dissemination of SP drug resistance genes in Wenzhou City. PMID: 27483416 [PubMed - in process]
Source: Medical Science Monitor - August 4, 2016 Category: Research Tags: Med Sci Monit Source Type: research

Flooding adds pathogenic Escherichia coli strains to the water sources in southern Khyber Pakhtunkhwa, Pakistan
Conclusion: ETEC and EPEC are the primary causes of water contamination in southern regions of Khyber Pakhtunkhwa province, Pakistan. Firm adherence to the prescribed drugs can decrease trends in antibiotic resistance.
Source: Indian Journal of Medical Microbiology - December 7, 2016 Category: Microbiology Authors: MS Shah M Eppinger S Ahmed AA Shah A Hameed F Hasan Source Type: research

Molecular detection and antimicrobial resistance profile of zoonotic Salmonella enteritidis isolated from broiler chickens in Kohat, Pakistan
Conclusion The present study for the first time reports S. enteritidis on the basis of spvb gene detection. The increased drug resistance in S. enteritidis is an emerging problem that could negatively impact efforts to prevent and treat broiler-transmitted S. enteritidis.
Source: Journal of the Chinese Medical Association - March 9, 2017 Category: Journals (General) Source Type: research

Serotype prevalence and antibiotic susceptibility patterns of pneumococcal isolates in Zunyi city, China.
CONCLUSION: We found a substantial increase in the annual number of pneumococcal isolates since 2014. The theoretical impact of PCV13 was high in children less than 2 years old, and penicillin might be effective against pneumococcal infections in this region. PMID: 29209675 [PubMed - in process]
Source: Saudi Medical Journal - December 8, 2017 Category: Middle East Health Tags: Saudi Med J Source Type: research

Primary and Secondary Antibiotic Resistance of Helicobacter pylori in Israeli Children and Adolescents.
CONCLUSIONS: Significantly higher resistance rates were found in previously treated patients, stressing the need to refrain from empiric treatment using the "test and treat strategy." Culture-based treatment strategy should be considered in all previously treated children. PMID: 29235736 [PubMed - in process]
Source: The Israel Medical Association Journal - December 14, 2017 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

Detection of antimicrobial resistance genes of Helicobacter pylori strains to clarithromycin, metronidazole, amoxicillin and tetracycline among Egyptian patients
Conclusion Data concerning antimicrobial resistance genes play an important role in empiric treatment of H. pylori infection. According to our results, H. pylori resistance to metronidazole and amoxicillin was relatively high. Clarithromycin is still a good option for first line anti-H. pylori treatment. Combined resistant strains are emerging and may have an effect on the combination therapy.
Source: Egyptian Journal of Medical Human Genetics - March 9, 2018 Category: Genetics & Stem Cells Source Type: research

Trends in antimicrobial resistance patterns of Group A streptococci, molecular basis and implications
Conclusion: The erythromycin and tetracycline resistance in GAS continues to exist at high levels and may be attributed to the over-prescription and use of these antibiotics. Our findings indicate that the use of these antibiotics especially macrolides as empiric therapy in penicillin-allergic patients may not be appropriate.
Source: Indian Journal of Medical Microbiology - August 7, 2018 Category: Microbiology Authors: Tintu Abraham Sujatha Sistla Source Type: research

Antibiotic resistance in Helicobacter pylori: A mutational analysis from a tertiary care hospital in Kashmir, India
Conclusions: Tetracycline and quinolones could be the antibiotics of choice in the eradication of H. pylori in this region, while recurrence of the infection with H. pylori could be expected among patients receiving either metronidazole or clarithromycin, for eradication therapy. DST should be done on a routine basis utilising both phenotypic and genotypic methods to prevent further emergence of resistance in this region.
Source: Indian Journal of Medical Microbiology - August 7, 2018 Category: Microbiology Authors: Fayaz Ahmad Wani Gulnaz Bashir Mushtaq Ahmad Khan Showkat Ali Zargar Zubaida Rasool Qurteeba Qadri Source Type: research

Alarming resistance of Neisseria gonorrhoeae in a tertiary care hospital of North India
Conclusion: Alarming increase in the resistance to commonly used antimicrobials for gonorrhoea in our study, especially of fluoroquinolones, is a clarion call for the urgent need for prudence in prescribing them. Observing the rampant resistance exhibited by N. gonorrhoeae, it is clear that the day is not far when it will acquire a superbug status and become intractable to treatment by the available antibiotics.
Source: Indian Journal of Medical Microbiology - August 7, 2018 Category: Microbiology Authors: Mohit Sharma Meher Rizvi Richa Gupta Mohd Azam Haris M Khan Anjum Parvez Indu Shukla Source Type: research

Investigating the effect of tetracycline addition on nanocomposite hydrogels based on polyvinyl alcohol and chitosan nanoparticles for specific medical applications.
Abstract Hydrogels have been used in many biomedical applications such as drug delivery and tissue engineering in recent decades. To improve the physiochemical and antimicrobial properties of these hydrogels and developing their applications, hybrid systems consisting of hydrogels, biodegradable nanoparticles and antibiotics were synthesized. In this regard, nanocomposite hydrogels based on PVA, 5% chitosan nanoparticles (NC) and various contents of tetracycline were prepared using freezing-thawing cycles and characterized using Fourier transform infrared spectroscopy (FTIR), gel fraction, swelling, antibacterial ...
Source: International Journal of Biological Macromolecules - October 17, 2018 Category: Biochemistry Authors: Parsa P, Paydayesh A, Davachi SM Tags: Int J Biol Macromol Source Type: research

In vitro activity of mecillinam and nitroxoline against Neisseria gonorrhoeae - re-purposing old antibiotics in the multi-drug resistance era.
Abstract In 2018, the European Centre for Disease Prevention and Control reported the first cases of extensively drug-resistant Neisseria gonorrhoeae infections in Europe. Seeking new options for antimicrobial therapy we investigated the susceptibility of N. gonorrhoeae to nitroxoline (NIT) and mecillinam (MCM), both of which are currently only indicated to treat uncomplicated urinary tract infections. Clinical N. gonorrhoeae isolates with non-susceptibility to penicillin from two German medical centres were included (n =27). Most isolates were also non-susceptible to a range of other anti-gonococcal antimicrobial...
Source: Journal of Medical Microbiology - June 3, 2019 Category: Microbiology Authors: Fuchs F, Wille J, Hamprecht A, Parcina M, Lehmann C, Schwarze-Zander C, Seifert H, Higgins PG Tags: J Med Microbiol Source Type: research

Investigation of antimicrobial resistance and virulence genes of Campylobacter isolates from patients in a tertiary hospital in Edirne, Turkey
Conclusions: It was detected that there is an increase in antimicrobial resistance of Campylobacter strains in our region, and most of the isolates harbour virulence genes.
Source: Indian Journal of Medical Microbiology - August 28, 2020 Category: Microbiology Authors: Canan Eryildiz Kiymet Tabakcioglu Gulcan Kuyucuklu Nermin Sakru Source Type: research

Prevalence, toxin gene profile, genotypes and antibiotic susceptibility of Clostridium difficile in a tertiary care hospital in Taif, Saudi Arabia
Conclusion: Further larger studies are required for an accurate understanding of CDI epidemiology in Saudi Arabia.
Source: Indian Journal of Medical Microbiology - August 28, 2020 Category: Microbiology Authors: Taisir Saber Yousry A Hawash Khadiga A Ismail Amany S Khalifa Khalaf F Alsharif Saleh A Alghamdi Tamer Saber Emad M Eed Source Type: research