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Drug: Tetracycline
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Total 6458 results found since Jan 2013.
Prolonged course of eravacycline leading to acute pancreatitis
We describe a 46-year-old male who received eravacycline for treatment of a perirectal abscess. While the patient had slightly elevated lipase levels at baseline post-cardiopulmonary arrest, he developed abdominal pain and a further increase in lipase levels following 10 days of eravacycline, consistent with pancreatitis. Based on the Naranjo adverse drug reaction probability scale, eravacycline was the probable etiology of acute pancreatitis given improvement immediately after discontinuation. Clinicians should be aware of this potential adverse effect of eravacycline and should not initiate eravacycline in those with ris...
Source: The American Journal of the Medical Sciences - September 16, 2023 Category: General Medicine Authors: Sylvia Stefanos Lyndsey Davis Amruta Panwala Michael S Gelfand Chinelo N Animalu B Tate Cutshall Source Type: research
Multiple carbapenem hydrolyzing genes in clinical isolates of Acinetobacter baumannii
Conclusions: This is the first study from North India, which comprehensively detected the presence of multiple carbapenemases as well the blaNDM-1 gene. The presence of the novel gene blaNDM-1 indicated ability of A. baumannii to acquire new carbapenemase genes despite the existence of multiple carbapenemase genes. The present study confirmed the presence of multiple genetic mechanisms for carbapenemases production among the clinical isolates of A. baumannii in north India.
Source: Indian Journal of Medical Microbiology - July 25, 2013 Category: Microbiology Authors: DK NiranjanNP SinghV ManchandaS RaiIR Kaur Source Type: research
Resistotype of Helicobacter pylori isolates: the impact on eradication outcome.
This study showed that frameshift and nonsense mutations in rdxA or frxA genes and point mutations in the 23S rRNA affected the efficacy of H. pylori eradication therapy.
PMID: 24757218 [PubMed - in process]
Source: Journal of Medical Microbiology - April 26, 2014 Category: Microbiology Authors: Alfizah H, Norazah A, Hamizah R, Ramelah M Tags: J Med Microbiol Source Type: research
Transfer patterns of integron-associated and antibiotic resistance genes in S. flexneri during different time intervals in Tianjin, China
Conclusion: Of the 32 strains of S. flexneri isolated from 1981 to 1983 and stored in our laboratory, class 1 integron was detected in 28 strains (87.50%), while 27 strains (84.37%) harboured an aminoglycoside resistance gene, aadA, in the variable region of their integrons. Class 1 integron was identified in 22 (91.67%) of the 24 S. flexneri strains isolated from 2009 to 2010, whereas the variable region and 3′-end amplification were not present in any of the strains. Class 2 integron was not found in the 1981-1983 group (group A) of strains; although 19 (79.17%) of the 24 strains ...
Source: Indian Journal of Medical Microbiology - July 10, 2014 Category: Microbiology Authors: J WangF LiangX-Mei WuW Qi Source Type: research
Erythromycin-resistant genes in group A β-haemolytic Streptococci in Chengdu, Southwestern China
Conclusions: The main phenotype is cMLS, and the ermB gene code is the main resistance mechanism against macrolides in GAS. Penicillin is the most beneficial for treating GAS infection, and is still used as first-line treatment. And macrolide antibiotics are not recommended for treatment of GAS infection in children because of the high rates of antimicrobial resistance in mainland China.
Source: Indian Journal of Medical Microbiology - July 10, 2014 Category: Microbiology Authors: W ZhouYM JiangHJ WangLH KuangZQ HuH ShiM ShuCM Wa Source Type: research
Emerging antimicrobial resistance pattern of Helicobacter pylori in central Gujarat
Conclusion: A very high percentage of patients were infected with metronidazole and clarithromycin resistant strains. The use of antibiotics for other indications seems to be the major risk factor for the development of primary resistance. High incidence should alarm the gastroenterologist while prescribing the eradication regimen.
Source: Indian Journal of Medical Microbiology - October 4, 2014 Category: Microbiology Authors: HB PandyaHarihar Har AgravatJS PatelNRK Sodagar Source Type: research
Role of Polymerase Chain Reaction (PCR) in the detection of antibiotic-resistant Staphylococcus aureus
Conclusion This study showed that the PCR is a specific and effective method for classifying and identifying isolates of S. aureus, which demonstrated increasing resistance against many antibiotics.
Source: Egyptian Journal of Medical Human Genetics - October 12, 2014 Category: Genetics & Stem Cells Source Type: research
Bacterial adhesion to antibiotic-loaded guided tissue regeneration membranes – A scanning electron microscopy study
Conclusion Incorporation of tetracycline or amoxicillin greatly reduced adhesion of S. mutans or A. actinomycetemcomitans on the ePTFE, glycolide fiber, or collagen membranes. This finding indicates that it is valuable and effective to use the antibiotic-loaded GTR membranes for periodontal regeneration therapy.
Source: Journal of the Formosan Medical Association - January 24, 2015 Category: Journals (General) Source Type: research
Pyonephrosis due to Chryseobacterium gleum: A first case report
S Garg, SB Appannanavar, B Mohan, N TanejaIndian Journal of Medical Microbiology 2015 33(2):311-313Chryseobacterium spp are widely distributed in nature but data of their isolation from clinical samples is scanty. Here, we report the first case of AmpC producing C. gleum causing pyonephrosis in a patient having bilateral nephrolithiasis on double J (DJ) stent. The present isolate was resistant to vancomycin, erythromycin, clindamycin, carbapenems and ciprofloxacin and susceptible to tetracycline and minocycline. The patient was treated with tetracycline and recovered without the need for removal of the DJ stent. The enviro...
Source: Indian Journal of Medical Microbiology - April 10, 2015 Category: Microbiology Authors: S GargSB AppannanavarB MohanN Taneja Source Type: research
A comparative analysis of root surface biomodification with ethylene diamine tetra acetic acid and tetracycline hydrochloride: An in vitro scanning electron microscopic study
Conclusion The EDTA produced better effects than tetracycline by providing more demineralized area and collagen exposure at a neutral pH.
Source: Medical Journal Armed Forces India - May 1, 2015 Category: Journals (General) Source Type: research
The generation of a ZBTB16-inducible expression system in the ACHN adenocarcinoma cell line
Conclusion The firm regulation of transcription factor expression in cancer cell models is very important in investigating their biological roles. Many transcription factors, such as ZBTB16, will carry on their biological activities even with minimal expression levels. The Tet-On® 3G system was essential in controlling the basal expression to prevent transcription leakage and providing a tightly regulated method for expressing ZBTB16 in a manner resembling physiological conditions.
Source: Journal of Taibah University Medical Sciences - June 10, 2015 Category: Universities & Medical Training Source Type: research
Clinical significance of various diagnostic techniques and emerging antimicrobial resistance pattern of Helicobacter Pylori from Gastric Biopsy Samples
Conclusion: H and E is taken as the gold standard according to CDC. Urease test is a better screening procedure than culture. H pylori resistance to metronidazole in our zone was highest. This is due to general and extensive use of metronidazole for other infectious diseases. Our study suggests need for a systematic approach to determine antibiogram of the strains before considering the drug regimens.
Source: Indian Journal of Medical Microbiology - October 16, 2015 Category: Microbiology Authors: MA VagaraliSC MetgudH BannurSG KaradesaiJM Nagmoti Source Type: research
Prevalence of vancomycin resistant Staphylococcus aureus (VRSA) in methicillin resistant S. aureus (MRSA) strains isolated from burn wound infections
Conclusion A significant fraction of VRSA was found among MRSA strains in this study, revealing the necessity for new and effective drugs against MRSA.
Source: Tzu Chi Medical Journal - April 23, 2016 Category: Universities & Medical Training Source Type: research
Prevalence of vancomycin resistant Staphylococcus aureus (VRSA) in methicillin resistant S. aureus (MRSA) strains isolated from burn wound infections
Conclusion A significant fraction of VRSA was found among MRSA strains in this study, revealing the necessity for new and effective drugs against MRSA.
Source: Tzu Chi Medical Journal - July 20, 2016 Category: Universities & Medical Training Source Type: research
