Postoperative herpetic endophthalmitis —A case report
We report a case of herpetic endophthalmitis following cataract surgery. A 65-year-old man underwent uneventful phacoemulsification and vision improved within the first few postoperative days. However, visual loss with an anterior chamber reaction of ++++ and a ++ vitreous cell were noted in the 4th postoperative week. Repeated intravitreal injection of vancomycin and ceftriaxone, pars plana vitrectomy and removal of the intraocular lens (IOL), and the capsular bag were performed sequentially but in vain. Bacterial, mycobacterial, and fungal culture of the IOL and capsular bag demonstrated negative findings. Path...
Source: Tzu Chi Medical Journal - November 22, 2016 Category: Universities & Medical Training Source Type: research

HLA haplotype in association with the low incidence C*07:66 allele found by case analysis of Taiwanese and mainland Chinese individuals
Conclusion The information on the ethnicity of the C*07:66 allele and the deduced probable HLA haplotype associated with the low-incidence C*07:66 allele reported in this study may aid in HLA testing laboratories for reference purposes. In addition, they can be used by stem cell transplant donor search coordinators to help create, for patients bearing this uncommon HLA allele, strategies for finding compatible donors using bone marrow donor registries comprising unrelated individuals. (Source: Tzu Chi Medical Journal)
Source: Tzu Chi Medical Journal - November 10, 2016 Category: Universities & Medical Training Source Type: research

Role of micronutrients in congestive heart failure: A systematic review of randomized controlled trials
Conclusion Overall, this systematic review found sufficient evidence to support a large-scale trial on micronutrient supplementation in patients with heart failure. (Source: Tzu Chi Medical Journal)
Source: Tzu Chi Medical Journal - November 1, 2016 Category: Universities & Medical Training Source Type: research

Characteristics and outcomes of patients with emergency department revisits within 72  hours and subsequent admission to the intensive care unit
Conclusion Most of the patients who revisited the ED within 72 hours and were subsequently admitted to the ICU visited the ED during the evening shift and were categorized into triage Level III on their first visit. The most common chief complaint at the first visit was abdominal pain. The most common cause of revisits with ICU admission was doctor-related, while the most common underlying disease was hypertension. Significantly higher mortality was observed after ED revisits in patients with lower triage scores with underlying malignancy and liver cirrhosis. (Source: Tzu Chi Medical Journal)
Source: Tzu Chi Medical Journal - September 17, 2016 Category: Universities & Medical Training Source Type: research

Therapeutic hypothermia brings favorable neurologic outcomes in children with near drowning
Publication date: Available online 15 September 2016 Source:Tzu Chi Medical Journal Author(s): Ming-Chun Chen, Chia-Hsiang Chu, Ching-Feng Cheng, Jun-Song Lin, Jui-Hsia Chen, Yu-Hsun Chang A 1-year-10-month-old boy was admitted to our pediatric intensive care unit due to near drowning with pulmonary edema. A conventional ventilator with 100% oxygen supplementation was used initially, but was shifted to high frequency oscillatory ventilation as his oxygen saturation was around 84–88%. Therapeutic hypothermia was applied due to hypoxic ischemic encephalopathy with severe acidosis. His respiratory condition improved an...
Source: Tzu Chi Medical Journal - September 15, 2016 Category: Universities & Medical Training Source Type: research

Isolated complete dislocation of the tarsal navicular without fracture:  A rare injury
We present a 64-year-old diabetic man whose tarsal navicular was completely dislocated without fracture following a traffic accident. The most probable mechanism of injury was an abduction–pronation injury causing a midtarsal dislocation, and on spontaneous reduction, the navicular was dislocated medially. This mechanism is similar to perilunate dislocation. Computed tomography of the involved foot was done to accurately define the full extent of the bony injury and magnetic resonance imaging was required to determine if there was a ligamentous injury and to assess the attachment of soft tissues to the displaced bone...
Source: Tzu Chi Medical Journal - September 3, 2016 Category: Universities & Medical Training Source Type: research

Side-branch wire entrapment: Early recognition and management
We report early recognition of SBW entrapment in a 60-year-old woman. (Source: Tzu Chi Medical Journal)
Source: Tzu Chi Medical Journal - September 3, 2016 Category: Universities & Medical Training Source Type: research

Insidious malignant triton tumor of the chest wall with late flare-up
We present a 76-year-old man with an insidious chest wall tumor with late progressive painful enlargement and pleural and pulmonary involvement. Complete resection of the affected thoracic wall as well as single separate lesions in the parietal pleura and left upper lung was carried out. The pathological examination confirmed that it was a malignant triton tumor. The patient received adjuvant chemoradiotherapy but eventually succumbed to disease relapse and distant metastases 6 months after the surgery. (Source: Tzu Chi Medical Journal)
Source: Tzu Chi Medical Journal - September 3, 2016 Category: Universities & Medical Training Source Type: research

Effects of caffeine on cell viability and activity of histone deacetylase 1  and histone acetyltransferase in glioma cells
Conclusion Our data suggest that a new strategy, caffeine, could increase glioma cell death by decreasing HDAC1 activity and/or by increasing p300 activity. The changes in HDAC1 and p300 activities appeared to occur earlier than loss of RT2 cells. (Source: Tzu Chi Medical Journal)
Source: Tzu Chi Medical Journal - September 3, 2016 Category: Universities & Medical Training Source Type: research

Emergence of carbapenemase-producing urinary isolates at a tertiary  care hospital in Dhaka, Bangladesh
Conclusion The study shows a significant rate of urinary isolates were carbapenemase producers, including a high prevalence of blaNDM-1, in Bangladesh. (Source: Tzu Chi Medical Journal)
Source: Tzu Chi Medical Journal - September 3, 2016 Category: Universities & Medical Training Source Type: research

Botulinun A toxin urethral sphincter injection for neurogenic or  nonneurogenic voiding dysfunction
This article reviews recent studies of urethral sphincter BoNT-A treatment for voiding dysfunction. (Source: Tzu Chi Medical Journal)
Source: Tzu Chi Medical Journal - September 3, 2016 Category: Universities & Medical Training Source Type: research

Botulinun A toxin urethral sphincter injection for neurogenic or nonneurogenic voiding dysfunction
This article reviews recent studies of urethral sphincter BoNT-A treatment for voiding dysfunction. (Source: Tzu Chi Medical Journal)
Source: Tzu Chi Medical Journal - August 27, 2016 Category: Universities & Medical Training Source Type: research

Eosinophil-rich granuloma of the liver
Publication date: Available online 1 August 2016 Source:Tzu Chi Medical Journal Author(s): Ming-Hsun Li, Yung-Hsiang Hsu (Source: Tzu Chi Medical Journal)
Source: Tzu Chi Medical Journal - August 2, 2016 Category: Universities & Medical Training Source Type: research

Effects of caffeine on cell viability and activity of histone deacetylase 1 and histone acetyltransferase in glioma cells
Conclusion Our data suggest that a new strategy, caffeine, could increase glioma cell death by decreasing HDAC1 activity and/or by increasing p300 activity. The changes in HDAC1 and p300 activities appeared to occur earlier than loss of RT2 cells. (Source: Tzu Chi Medical Journal)
Source: Tzu Chi Medical Journal - August 2, 2016 Category: Universities & Medical Training Source Type: research

Deduced probable HLA haplotypes associated with HLA-C*04:82 found by case analysis of Taiwanese individuals
Conclusion The ethnicity of the C*04:82 allele and the deduced probable HLA haplotypes associated with the low-incidence C*04:82 allele are of value for reference purposes for HLA testing laboratories. In addition, they can be used by search coordinators to aid the creation of a strategy for finding compatible stem cell donors for patients who carry this uncommon HLA allele. (Source: Tzu Chi Medical Journal)
Source: Tzu Chi Medical Journal - July 29, 2016 Category: Universities & Medical Training Source Type: research

Comparison between the Trachway video intubating stylet and Macintosh laryngoscope in four simulated difficult tracheal intubations: A manikin study
Conclusion The learning time for tracheal intubation using the TVI stylet in difficult airway scenarios was short. Use of the TVI stylet was easier and required a shorter TTI for tracheal intubation in the tongue edema and combined scenarios. (Source: Tzu Chi Medical Journal)
Source: Tzu Chi Medical Journal - July 27, 2016 Category: Universities & Medical Training Source Type: research

Extracranial –intracranial bypass in the treatment of complex or giant internal carotid artery aneurysms
Conclusions Cerebral revascularization plays an important role in the treatment of complex ICA aneurysms that have a significant mass effect on the optic nerve or require occlusion of the parent ICA as a salvage procedure. (Source: Tzu Chi Medical Journal)
Source: Tzu Chi Medical Journal - July 20, 2016 Category: Universities & Medical Training Source Type: research

Guillain –Barré syndrome complicating dengue fever: Two case reports
Publication date: Available online 17 November 2015 Source:Tzu Chi Medical Journal Author(s): Yang Liang Boo, Mohd Azman M. Aris, Pek Woon Chin, Wan Aliaa Wan Sulaiman, Hamidon Basri, Fan Kee Hoo Guillain–Barré syndrome is a rare neurological manifestation associated with dengue infection. More common antecedent infections include Campylobacter jejuni and Cytomegalovirus infection. Here, we report two cases of Guillain–Barré syndrome complicating dengue infection. (Source: Tzu Chi Medical Journal)
Source: Tzu Chi Medical Journal - July 20, 2016 Category: Universities & Medical Training Source Type: research

Adolescent onset of vertically transmitted untreated AIDS: A report of  one case
Publication date: Available online 3 February 2016 Source:Tzu Chi Medical Journal Author(s): Hsi-Hsien Wei, Li-Ping Tsai, Ping-Sheng Wu A 12-year-old adolescent girl with intractable pneumonia and desaturation was sent to our hospital. An immunocompromised state was highly suspected because of an oral thrush persisting for a year and pneumonia of unusual severity. Laboratory tests confirmed she had human immunodeficiency virus (HIV) infection and full-blown AIDS. She lived with her adopted parents and reported no history of sexual abuse, drug abuse, or blood transfusion. We contacted the Center of Disease Control and ...
Source: Tzu Chi Medical Journal - July 20, 2016 Category: Universities & Medical Training Source Type: research

Practical points in the medical treatment of overactive bladder and  nocturia in the elderly
Publication date: March 2016 Source:Tzu Chi Medical Journal, Volume 28, Issue 1 Author(s): Jing-Liang Chen, Sheng-Fu Chen, Yuan-Hong Jiang, Hann-Chorng Kuo The prevalence of overactive bladder (OAB) increases with age. Degeneration of the central nervous system in the elderly has been proposed as one of the pathogenic factors of OAB. Antimuscarinic therapy is effective in the treatment of OAB; however, intolerable systemic adverse events and cognitive dysfunction during treatment with nonselective antimuscarinic agents is of growing concern in elderly patients. The newly developed beta-3 adrenoceptor agonist mirabegr...
Source: Tzu Chi Medical Journal - July 20, 2016 Category: Universities & Medical Training Source Type: research

Prevalence of vancomycin resistant Staphylococcus aureus (VRSA) in methicillin resistant S.  aureus (MRSA) strains isolated from burn wound infections
Conclusion A significant fraction of VRSA was found among MRSA strains in this study, revealing the necessity for new and effective drugs against MRSA. (Source: Tzu Chi Medical Journal)
Source: Tzu Chi Medical Journal - July 20, 2016 Category: Universities & Medical Training Source Type: research

Minimal deviation adenocarcinoma of the uterine cervix: A case report
Publication date: June 2016 Source:Tzu Chi Medical Journal, Volume 28, Issue 2 Author(s): Dah-Ching Ding, Tang-Yuan Chu, Yung-Hsiang Hsu Minimal deviation adenocarcinoma (MDA) of the uterine cervix is a rare disease. The rate of misdiagnosis is relatively high and there is no standard treatment. A 58-year-old woman presented with an abnormal Pap smear revealing atypical glandular cells and vaginal mucoid discharge. Cervical biopsy revealed cervicitis and an endometrium with atypical glands and increasing mitoses. A frozen section of curetted endometrial tissue revealed adenocarcinoma. Surgical staging with laparoscopi...
Source: Tzu Chi Medical Journal - July 8, 2016 Category: Universities & Medical Training Source Type: research

Validity and reliability of swallowing screening tools used by nurses for dysphagia: A systematic review
Publication date: June 2016 Source:Tzu Chi Medical Journal, Volume 28, Issue 2 Author(s): Jiin-Ling Jiang, Shu-Ying Fu, Wan-Hsiang Wang, Yu-Chin Ma Dysphagia following neurological impairment increases the risk of dehydration, malnutrition, aspiration pneumonia, and even death. Screening for dysphagia has been reported to change negative outcomes. This review evaluated the validity and reliability of measurement tools for screening dysphagia in patients with neurological disorders to identify a feasible tool that can be used by nurses. Electronic databases were searched for studies from 1992 to 2015 related to dyspha...
Source: Tzu Chi Medical Journal - July 8, 2016 Category: Universities & Medical Training Source Type: research

Prenatal diagnosis of the maternal derivative chromosome der(15)t(Y;15)(q12;p13) in a dizygotic twin pregnancy
Publication date: Available online 2 July 2016 Source:Tzu Chi Medical Journal Author(s): Pei-Yi Chen, Jui-Hung Yen, Ching-Feng Cheng, Pao Chu Chen, Yi-Shian Li, Tzu-Ying Li, Chung-Nan Yeh, Jye-Siung Fang Sex chromosome translocations are unique and must be considered separately from translocations between autosomes. Here, we describe the first prenatal case of one twin fetus with an unbalanced translocation between chromosome Y and chromosome 15, presenting a 46,XY,der(15)t(Y;15) karyotype. The other twin had a normal 46,XY karyotype. Cytogenetic analysis of the parental chromosomes revealed that the father had a...
Source: Tzu Chi Medical Journal - July 8, 2016 Category: Universities & Medical Training Source Type: research

Conceptualizing workplace based assessment in Singapore: Undergraduate Mini-Clinical Evaluation Exercise experiences of students and teachers
Conclusion The mini-CEX is an effective assessment tool, but is limited by barriers to administration and evaluation. Differing opinions and expectations between tutors and students could provide an interesting focal point for future studies. (Source: Tzu Chi Medical Journal)
Source: Tzu Chi Medical Journal - July 8, 2016 Category: Universities & Medical Training Source Type: research

Solitary adrenal tuberculosis
Publication date: Available online 3 June 2016 Source:Tzu Chi Medical Journal Author(s): Yen-Chang Chen, Yung-Hsiang Hsu (Source: Tzu Chi Medical Journal)
Source: Tzu Chi Medical Journal - June 2, 2016 Category: Universities & Medical Training Source Type: research

Estrogen and G protein-coupled estrogen receptor agonist G-1 cause relaxation of human gallbladder
Conclusion These results demonstrate for the first time that 17β-estradiol and GPER agonist G-1 cause relaxation of the human gallbladder, probably through GPER. Estrogen might play an important role in the control of human gallbladder motility. (Source: Tzu Chi Medical Journal)
Source: Tzu Chi Medical Journal - May 31, 2016 Category: Universities & Medical Training Source Type: research

Emergence of carbapenemase-producing urinary isolates at a tertiary care hospital in Dhaka, Bangladesh
Conclusion The study shows a significant rate of urinary isolates were carbapenemase producers, including a high prevalence of blaNDM-1, in Bangladesh. (Source: Tzu Chi Medical Journal)
Source: Tzu Chi Medical Journal - May 27, 2016 Category: Universities & Medical Training Source Type: research

Wegener's granulomatosis that mimics nasopharyngeal cancer
Publication date: Available online 28 May 2016 Source:Tzu Chi Medical Journal Author(s): Chih-Wei Liu, Yung-Hsiang Hsu (Source: Tzu Chi Medical Journal)
Source: Tzu Chi Medical Journal - May 27, 2016 Category: Universities & Medical Training Source Type: research

Inverse relationship of bone mineral density and serum level of N-terminal pro-B-type natriuretic peptide in peritoneal dialysis patients
Conclusion A high serum level of NT-pro-BNP and low body weight were associated with poor BMD in PD patients. (Source: Tzu Chi Medical Journal)
Source: Tzu Chi Medical Journal - May 27, 2016 Category: Universities & Medical Training Source Type: research

Deduced probable HLA-C*07:359-associated human leukocyte antigen haplotypes found by case analysis of Taiwanese unrelated bone marrow hematopoietic stem cell donors
Conclusion Information on the ethnicity of the C*07:359 allele and its deduced probable HLA haplotypes that are associated with the low-incidence C*07:359 allele reported here are of value to HLA testing laboratories for reference purposes. In addition, they can be used by stem cell transplantation donor search coordinators to determine a strategy for finding compatible donors using unrelated bone marrow donor registries when patients carry this uncommon HLA allele. (Source: Tzu Chi Medical Journal)
Source: Tzu Chi Medical Journal - May 26, 2016 Category: Universities & Medical Training Source Type: research

Successful treatment of a newborn with congenital hyperinsulinism having a novel heterozygous mutation in the ABCC8 gene using subtotal pancreatectomy
Publication date: Available online 27 May 2016 Source:Tzu Chi Medical Journal Author(s): Chi-Feng Yen, Chi-Yu Huang, Chon-In Chan, Chiung-Hsing Hsu, Nien-Lu Wang, Tao-Yeuan Wang, Chiung-Ling Lin, Wei-Hsin Ting Congenital hyperinsulinism (CHI) is the most common cause of persistent hypoglycemia in newborns and infants. CHI is characterized by unregulated secretion of insulin from pancreatic β cells. Here, we reported the case of a large-for-gestational-age, full-term newborn that suffered from CHI and developed severe and persistent hypoglycemia at an early stage of life. The infant was nearly unresponsive to...
Source: Tzu Chi Medical Journal - May 26, 2016 Category: Universities & Medical Training Source Type: research

Appendicular foreign body presenting with appendicular mass
Publication date: Available online 28 April 2016 Source:Tzu Chi Medical Journal Author(s): Andy Shau-Bin Chou, Yung-Hsiang Hsu, Bor-Gang Wu (Source: Tzu Chi Medical Journal)
Source: Tzu Chi Medical Journal - April 28, 2016 Category: Universities & Medical Training Source Type: research

Prevalence of vancomycin resistant Staphylococcus aureus (VRSA) in methicillin resistant S. aureus (MRSA) strains isolated from burn wound infections
Conclusion A significant fraction of VRSA was found among MRSA strains in this study, revealing the necessity for new and effective drugs against MRSA. (Source: Tzu Chi Medical Journal)
Source: Tzu Chi Medical Journal - April 23, 2016 Category: Universities & Medical Training Source Type: research

Neurophysiological comparisons of subthalamic deep-brain stimulation for Parkinson's disease between patients receiving general and local anesthesia
Conclusion Although the GA group has a lower neuronal firing frequency in the STN during surgery, STN-DBS under GA showed comparable and non-inferior outcomes as compared with STN-DBS under LA. (Source: Tzu Chi Medical Journal)
Source: Tzu Chi Medical Journal - April 11, 2016 Category: Universities & Medical Training Source Type: research

Granulosa cell tumor of the ovary
Publication date: Available online 27 March 2016 Source:Tzu Chi Medical Journal Author(s): Cheng-Fa Chou, Wen-Chih Huang (Source: Tzu Chi Medical Journal)
Source: Tzu Chi Medical Journal - March 26, 2016 Category: Universities & Medical Training Source Type: research

Extraskeletal osteosarcoma in the back
Publication date: March 2016 Source:Tzu Chi Medical Journal, Volume 28, Issue 1 Author(s): Shu-Mei Chang, Chien-Chin Chen, Chien-Liang Fang, Chun-Liang Tung (Source: Tzu Chi Medical Journal)
Source: Tzu Chi Medical Journal - March 16, 2016 Category: Universities & Medical Training Source Type: research

Outbreak of multidrug-resistant tuberculosis in an aboriginal family in eastern Taiwan
Publication date: March 2016 Source:Tzu Chi Medical Journal, Volume 28, Issue 1 Author(s): Tao Qian Tang, Ser-Chen Fu, Ying-Huei Chen, Shun-Tien Chien, Jen-Jyh Lee, Chih-Bin Lin Spread of multidrug-resistant tuberculosis (MDR-TB) strains in the general population presents a serious threat to public health and severely threatens existing control efforts. Techniques such as spoligotyping and Mycobacterium interspersed repetitive units—variable-number tandem-repeat typing of mycobacterial isolates have been employed to confirm familial outbreaks of MDR-TB. We diagnosed and traced four MDR-TB cases in a family vi...
Source: Tzu Chi Medical Journal - March 16, 2016 Category: Universities & Medical Training Source Type: research

Microfilaria in a thyroid nodule discovered by fine needle aspiration cytology
Publication date: March 2016 Source:Tzu Chi Medical Journal, Volume 28, Issue 1 Author(s): A. Hakeem, A. Mahmood Filariasis is a major health problem in tropical countries, including India. The disease is endemic all over India, especially in Uttar Pradesh, Andhra Pradesh, Orissa, Bihar, Jharkhand, Tamil Nadu, Kerala, and Gujarat. A heavy parasitic load may appear in the blood, urine with chyle, and at times in scrotal aspirates. It is very unusual to find microfilaria in thyroid aspirate. Here, we present a rare case in which microfilaria was found during fine needle aspiration cytology of a solitary thyroid nodule. (...
Source: Tzu Chi Medical Journal - March 16, 2016 Category: Universities & Medical Training Source Type: research

Prognostic factors of paranasal sinusitis with intracranial invasion: A 14-year review of cases at Hualien Buddhist Tzu Chi Hospital
Publication date: March 2016 Source:Tzu Chi Medical Journal, Volume 28, Issue 1 Author(s): Kuan-Pin Chen, Yu-Cheng Chou, Chia-Fone Lee, Tomor Harnod, Shin-Yuan Chen, Chain-Fa Su, Peir-Rong Chen, Tsung-Lang Chou Intracranial invasion of paranasal sinusitis is an emergency condition that requires surgical and medical intervention in order to avoid further deterioration. We surveyed patients at the Buddhist Tzu Chi Hospital (Hualien, Taiwan) who had paranasal sinusitis with intracranial invasion. A total of 505 patients with paranasal sinusitis were surveyed at Hualien Buddhist Tzu Chi Hospital over a 14-year period...
Source: Tzu Chi Medical Journal - March 16, 2016 Category: Universities & Medical Training Source Type: research

A deduced probable HLA-DRB1*16:35-associated HLA haplotype (A*11-B*13-DRB1*16:35) found in a case analysis of two Taiwanese unrelated bone marrow hematopoietic stem cell donors
Conclusion Information on the deduced probable HLA haplotype in association with the low incidence DRB1*16:35 allele that we report here is of value for HLA testing laboratories for reference purposes. In addition, it can be used by stem cell transplantation donor search coordinators to determine a strategy for finding compatible donors in unrelated bone marrow donor registries when a patient has this uncommon HLA allele. (Source: Tzu Chi Medical Journal)
Source: Tzu Chi Medical Journal - March 9, 2016 Category: Universities & Medical Training Source Type: research

Pathological findings of ketamine ureteritis
Publication date: Available online 26 February 2016 Source:Tzu Chi Medical Journal Author(s): Jiann-Der Wu, Chun-Liang Tung, Cheng-Sheng Chen, Shu-Mei Chang (Source: Tzu Chi Medical Journal)
Source: Tzu Chi Medical Journal - February 26, 2016 Category: Universities & Medical Training Source Type: research

Pancoast's tumor caused by diffuse large B-cell lymphoma
Publication date: June 2015 Source:Tzu Chi Medical Journal, Volume 27, Issue 2 Author(s): Han-Yi Wang, Jeng-Long Tsai, Chih-Yu Liang, Chih-Wei Hsu (Source: Tzu Chi Medical Journal)
Source: Tzu Chi Medical Journal - February 25, 2016 Category: Universities & Medical Training Source Type: research

Leiomyoma of the female urethra: A case report
Publication date: June 2015 Source:Tzu Chi Medical Journal, Volume 27, Issue 2 Author(s): Cheng-Sheng Chen, Chien-Chin Chen (Source: Tzu Chi Medical Journal)
Source: Tzu Chi Medical Journal - February 25, 2016 Category: Universities & Medical Training Source Type: research

Pauci-immune crescentic glomerulonephritis
Publication date: June 2015 Source:Tzu Chi Medical Journal, Volume 27, Issue 2 Author(s): Yung-Hsiang Hsu (Source: Tzu Chi Medical Journal)
Source: Tzu Chi Medical Journal - February 25, 2016 Category: Universities & Medical Training Source Type: research

Skull metastasis in urothelial cell carcinoma of the bladder
We present a case of occipital bone metastasis arising from a previously verified bladder urothelial carcinoma. An 81-year-old woman presented with a painless, nonpulsatile mass in the left occipital region of the scalp that had progressively increased for 1 year. Skull radiography demonstrated a large osteolytic lesion in the left occipital bone. Computed tomography of the head showed a 6.5 cm × 6.0 cm skull defect from the midline to the left occipital bone, overlying the posterior superior sagittal sinus. The patient underwent a wide craniectomy with en bloc removal of the mass. Because of wide...
Source: Tzu Chi Medical Journal - February 25, 2016 Category: Universities & Medical Training Source Type: research

Tenofovir nephropathy in a patient with human immunodeficiency virus
Publication date: June 2015 Source:Tzu Chi Medical Journal, Volume 27, Issue 2 Author(s): Wei-Shan Tsai, Lih-Shinn Wang, Yung-Hsiang Hsu, Yu-Li Lin, Te-Chao Fang, Bang-Gee Hsu Tenofovir is an effective and widely used antiretroviral drug for the treatment of both human immunodeficiency virus (HIV) and hepatitis B virus infection. Although large clinical studies and postmarketing data support a benign renal profile for tenofovir, numerous cases of kidney injury have raised concerns about its nephrotoxic potential. Here, we describe the case of a 33-year-old man with HIV who was treated with tenofovir, following whic...
Source: Tzu Chi Medical Journal - February 25, 2016 Category: Universities & Medical Training Source Type: research

Surgical outcomes of a modified Marmot operation with transverse cutting of the spinal process in patients with degenerative lumbar spinal stenosis
Conclusions A microscope-assisted modified Marmot operation combined with spinal process transverse cutting laminectomy was an effective procedure for spinal decompression. As the procedure produces only unilateral muscular trauma, patients can ambulate early. Overall, the procedure is safe and effective. It provides good surgical field exposure and satisfactory neurological and functional outcomes. (Source: Tzu Chi Medical Journal)
Source: Tzu Chi Medical Journal - February 25, 2016 Category: Universities & Medical Training Source Type: research

Effects of tetrandrine and caffeine on cell viability and expression of mammalian target of rapamycin, phosphatase and tensin homolog, histone deacetylase 1, and histone acetyltransferase in glioma cells
Conclusion Tetrandrine and caffeine can increase glioma cell death additively possibly via increasing p300 expression. (Source: Tzu Chi Medical Journal)
Source: Tzu Chi Medical Journal - February 25, 2016 Category: Universities & Medical Training Source Type: research

HLA-A*33-B*58:45-DRB1*03, a deduced probable human leukocyte antigen haplotype associated with a human leukocyte antigen low-incidence allele B*58:45 in Taiwanese unrelated hematopoietic bone marrow stem cell donors
Conclusion Information on this deduced probable HLA haplotype in association with the low-incidence B*58:45 allele is of value for HLA testing laboratories for reference purposes and can help bone marrow donor registries find compatible donors for patients with this uncommon HLA allele. (Source: Tzu Chi Medical Journal)
Source: Tzu Chi Medical Journal - February 25, 2016 Category: Universities & Medical Training Source Type: research