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Analysis of common allergens affecting patients with allergic rhinitis
This study aimed to identify the common allergens affecting patients with AR. A total of 52 patients with AR were identified for this study. AR was diagnosed based on the presenting symptoms and measurement of IgE levels and absolute eosinophil counts. Skin prick tests (SPT) were performed to identify the allergen sensitivity of the patients. Patient history, family history, and a detailed account of the symptoms were recorded. Finally, correlation between family history and allergy severity was statistically evaluated. All patients presented symptoms of rhinitis with sinusitis and 61.5% of these were mild or moderate alle...
Source: Bioinformation - September 18, 2023 Category: Bioinformatics Authors: Kumari Ranjana Maheshwari M Source Type: research

Analyzing airborne fungal concentration in Kolkata, India: temporal distribution, the effect of atmospheric parameters and health impact
AbstractAirborne fungal spores constitute a significant fraction of atmospheric bioparticles, and most of them are responsible for causing the respiratory allergy. The present study deals with the evaluation of fungal aerospora by microscopy-based and culture-based methods in one outdoor and six indoor microenvironments in Kolkata, India, from May 2014 to April 2017. The association of environmental parameters with spore concentrations was explored by Spearman ’s rank correlation analysis and multiple regression analysis. The impact of spore concentrations on the local population was assessed through a questionnaire surv...
Source: Air Quality, Atmosphere and Health - March 18, 2023 Category: Environmental Health Source Type: research

Clinico-demographic, radiological and immunological profile of allergic bronchopulmonary aspergillosis in a tertiary care institute of east India.
Conclusion: There was no significant association between lung function abnormalities and eosinophil count. ABPA-S was the most common finding among ABPA patients. High eosinophil count is associated with high incidence of bronchiectasis and hyper attenuated mucus (HAM) although severity of bronchiectasis is not directly related to higher peripheral eosinophil count. There may be some correlation between peripheral eosinophil count and total IgE but no significant correlation with aspergillus specific IgE.
Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Shankar, M., Ejazi, A., Chaubey, S., Kumar, D. Tags: 05.03 - Allergy and immunology Source Type: research

Identifying novel allergens from a common indoor mould Aspergillus ochraceus
This study aims to examine the allergenic potency of mycelial proteins of a common indoor fungus Aspergillus ochraceus to a selected atopic patient cohort as well as to identify the novel IgE-binding proteins through an immunoproteomic approach. 1-D and 2-D IgE specific western blot detected the IgE reactive proteins which were identified through MALDI-TOF/TOF and manual de novo peptide sequencing. The results revealed the detection of 10 cross-reactive IgE-binding proteins. Cluster analysis of 1-D immunoblot with individual patient sera identified NADP(+)-dependent glycerol dehydrogenase (GldB) homologous protein as a maj...
Source: Journal of Proteomics - February 24, 2021 Category: Biochemistry Authors: Sangeeta Roy Bodhisattwa Saha Swati Gupta Bhattacharya Source Type: research

Clinico-radiological and serological features in Allergic bronchopulmonary aspergillosis
Conclusions: There is a high prevalence of ABPA in asthmatic patients presenting at our hospital. The disease entity is still underrecognized in India, the vast majority of patients have bronchiectasis at presentation, and almost half are initially misdiagnosed as having pulmonary tuberculosis. There is a need to redefine the diagnostic criteria of ABPA and to develop a gold standard diagnostic test. This study places emphasis on using IgE levels specific for Aspergillus fumigatus as a screening test for ABPA.
Source: European Respiratory Journal - October 28, 2020 Category: Respiratory Medicine Authors: Prasanth, P. Tags: Allergy and immunology Source Type: research

Study of aero-allergen sensitization in subjects with naso-bronchial allergy in a tertiary care centre from India
Conference abstracts
Source: The Aspergillus Website - updates - August 20, 2020 Category: Respiratory Medicine Authors: MeganB Source Type: news

IgE-mediated occupational allergy to fungus among paddy field farmers of West Bengal, India: an aeromycological & immunological approach
IgE-mediated occupational allergy to fungus among paddy field farmers of West Bengal, India: an aeromycological& immunological approachConference abstracts
Source: The Aspergillus Website - updates - August 5, 2020 Category: Respiratory Medicine Authors: MeganB Source Type: news

Aerial fungal spectrum of Kolkata, India, along with their allergenic impact on the public health: a quantitative and qualitative evaluation
AbstractAirborne fungal spores are well documented to trigger respiratory allergy. The present study provides baseline information on the quantitative and qualitative aspects of aerospores for the first time in a typical urban area of Kolkata metropolis, India. An aeromonitoring was performed by Burkard volumetric 7-day sampler for two consecutive years (August 2012 –July 2014). Total concentration, seasonal variations and intradiurnal periodicities of fungal spores were estimated. Spearman’s rank correlation analysis was performed using various weather parameters. The prevalence of fungal spore allergy was investigate...
Source: Aerobiologia - September 17, 2018 Category: Environmental Health Source Type: research

Identification of Immuno-Reactive Proteins and Study of Immunogenic Peptides of the Major Allergen of Aspergillus terreus
This study is aimed to identify the allergens and determine their allergenic potency through immuno-biochemical methods from A. terreus, the most prevalent airborne allergenic fungus in West Bengal, India.
Source: Journal of Allergy and Clinical Immunology - February 1, 2018 Category: Allergy & Immunology Authors: Bijoya Karmakar, Swati Gupta Bhattacharya Source Type: research

Effect of seasonal variation on aeromycoflora of Bilaspur, Chhattisgarh, involved in allergic reactions
AbstractThe biotic (bacteria, fungi, pollen grains, algae) and abiotic (dust mites) factors present in the atmosphere are responsible for the common allergic reactions in humans. Fungi are one of the major biotic factors resulting in allergic conditions and sometimes lead to fatal diseases affecting vital organs. A detailed survey was carried out for 2  years (from May 2014 to April 2016) to assess the seasonal distribution and comparative diversity of aeromycoflora present in the urban and rural areas of Bilaspur, Chhattisgarh (India). During the survey, a marked variation in the types of fungal isolates and their coloni...
Source: Aerobiologia - November 13, 2017 Category: Environmental Health Source Type: research