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Update on perioperative hypersensitivity reactions: joint document from the Brazilian Society of Anesthesiology (SBA) and Brazilian Association of Allergy and Immunology (ASBAI) - Part II: etiology and diagnosis.
Authors: Solé D, Spindola MAC, Aun MV, Araújo Azi LMT, Bernd LAG, Garcia DB, Capelo AV, Cumino DO, Lacerda AE, Lima LC, Morato EF, Nunes RR, Rubini NPM, da Silva J, Tardelli MÂ, Watanabe AS, Curi EF, Sano F Abstract This second joint document, written by experts from the Brazilian Association of Allergy and Immunology (ASBAI) and Brazilian Society of Anesthesiology (SBA) concerned with perioperative anaphylaxis, aims to review the pathophysiological reaction mechanisms, triggering agents (in adults and children), and the approach for diagnosis during and after an episode of anaphylaxis. As anaphylaxis assessment...
Source: Revista Brasileira de Anestesiologia - December 16, 2020 Category: Anesthesiology Tags: Rev Bras Anestesiol Source Type: research

Update on perioperative hypersensitivity reactions: joint document from the Brazilian Society of Anesthesiology (SBA) and Brazilian Association of Allergy and Immunology (ASBAI) – part II: etiology and diagnosis
Publication date: Available online 1 November 2020Source: Brazilian Journal of Anesthesiology (English Edition)Author(s): Dirceu Solé, Maria Anita Costa Spindola, Marcelo Vivolo Aun, Liana Maria Tôrres de Araújo Azi, Luiz Antonio Guerra Bernd, Daniela Bianchi Garcia, Albertina Varandas Capelo, Débora de Oliveira Cumino, Alex Eustáquio Lacerda, Luciana Cavalcanti Lima, Edelton Flávio Morato, Rogean Rodrigues Nunes, Norma de Paula Motta Rubini, Jane da Silva, Maria Ângela Tardelli, Alexandra Sayuri Watanabe, Erick Freitas Curi, Flávio Sano
Source: Brazilian Journal of Anesthesiology - November 2, 2020 Category: Anesthesiology Source Type: research

Update on perioperative hypersensitivity reactions: joint document of the Brazilian Society of Anesthesiology (SBA) and Brazilian Association of Allergy and Immunology (ASBAI) - Part I: post-crisis guidelines and treatment.
Authors: Spindola MAC, Solé D, Aun MV, Azi LMTA, Bernd LAG, Garcia DB, Capelo AV, Cumino DO, Lacerda AE, Lima LC, Morato EF, Nunes RR, Rubini NPM, da Silva J, Tardelli MÂ, Watanabe AS, Curi EF, Sano F Abstract Experts from the Brazilian Association of Allergy and Immunology (ASBAI) and the Brazilian Society of Anesthesiology (SBA) interested in the issue of perioperative anaphylaxis, and aiming to strengthen the collaboration between the two societies, combined efforts to study the topic and to prepare a joint document to guide specialists in both areas. The purpose of the present series of two articles was to re...
Source: Revista Brasileira de Anestesiologia - October 22, 2020 Category: Anesthesiology Tags: Rev Bras Anestesiol Source Type: research

Update on perioperative hypersensitivity reactions: joint document of the Brazilian Society of Anesthesiology (SBA) and Brazilian Association of Allergy and Immunology (ASBAI) – Part I: post-crisis guidelines and treatment
Publication date: Available online 9 September 2020Source: Brazilian Journal of Anesthesiology (English Edition)Author(s): Maria Anita Costa Spindola, Dirceu Solé, Marcelo Vivolo Aun, Liana Maria Tôrres de Araújo Azi, Luiz Antonio Guerra Bernd, Daniela Bianchi Garcia, Albertina Varandas Capelo, Débora de Oliveira Cumino, Alex Eustáquio Lacerda, Luciana Cavalcanti Lima, Edelton Flávio Morato, Rogean Rodrigues Nunes, Norma de Paula Motta Rubini, Jane da Silva, Maria Ângela Tardelli, Alexandra Sayuri Watanabe, Erick Freitas Curi, Flávio Sano
Source: Brazilian Journal of Anesthesiology - September 9, 2020 Category: Anesthesiology Source Type: research

The Transcriptome of the Salivary Glands of Amblyomma aureolatum Reveals the Antimicrobial Peptide Microplusin as an Important Factor for the Tick Protection Against Rickettsia rickettsii Infection
Conclusion In conclusion, our data show that R. rickettsii exerts a modulatory effect on the transcriptional profile the SG of A. aureolatum. Moreover, RNAi experiments demonstrated that the knockdown of one microplusin increases the susceptibility of ticks to infection, suggesting that this is one important factor for the control of R. rickettsii. The functional characterization of the additional CDSs modulated by infection is warranted and might reveal other factors that interfere with the acquisition and/or transmission of this tick-borne pathogen. Ethics Statement All procedures involving vertebrate animals were car...
Source: Frontiers in Physiology - May 2, 2019 Category: Physiology Source Type: research

Blocking IL-19 Signaling Ameliorates Allergen-Induced Airway Inflammation
This study was carried out in accordance with the recommendations of the National Institutes of Health standards and guidelines for the care and use of experimental animals. The protocol was approved by the Animal Ethics Committee of National Cheng Kung University (IACUC NO. 107272 and 105077). Author Contributions J-YW and M-SC designed the study. Y-HW and Y-LL performed the experiments. Y-HW and W-YC analyzed the data. Y-HW, W-YC, and M-SC wrote the manuscript. W-YC and J-YW provided critical technical and scientific guidance and discussion. Funding This work was supported by research grant from the Ministry of Scien...
Source: Frontiers in Immunology - April 29, 2019 Category: Allergy & Immunology Source Type: research

Ketogenic Diet as a Treatment for Super-Refractory Status Epilepticus in Febrile Infection-Related Epilepsy Syndrome
Conclusions: The characteristic EEG pattern in the acute phase promoted timely diagnosis of FIRES. Our data suggest that KD may be a safe and promising therapy for FIRES with SRSE, and that early initiation of KD produces a favorable prognosis. Therefore, KD should be applied earlier in the course of FIRES. Intravenous KD can be an effective alternative route of administration for patients who may not take KD enterally. Introduction Febrile infection-related epilepsy syndrome (FIRES) is a rare epileptic encephalopathy of unknown etiology which occurs in patients without active epilepsy or underlying neurological diso...
Source: Frontiers in Neurology - April 25, 2019 Category: Neurology Source Type: research