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Predicting brain atrophy from resting-state functional connectivity and structural connectivity in ischemic stroke (P5.297)
Conclusions:Resting-state functional connectivity with the lesion location can predict atrophy of remote brain regions after ischemic stroke, independent of structural white-matter connectivity.Study Supported by: M.D.F. was supported by the National Institutes of Health (R21 MH099196, K23 NS083741), Dystonia Medical Research Foundation, National Parkinson’s Foundation, and NFL Players Association. A.J. was supported by a Postdoctoral Fellowship from the Natural Sciences and Engineering Research Council of Canada (NSERC PDF 454617). A.D.B. was supported by 4K12HD027748-24.Disclosure: Dr. Jannati has nothing to disclo...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Jannati, A., Boes, A. D., Horn, A., Pascual-Leone, A., Kuceyeski, A., Fox, M. D. Tags: Stroke Recovery and Rehabilitation Source Type: research

Clonic Perseveration after Acute Ischemic Stroke: An Insight into the Pathophysiological Mechanisms
Poststroke movement disorders may manifest as parkinsonism, dystonia, chorea, ballism, athetosis, tremor, myoclonus, stereotypies, and akathisia. In this article, we describe a patient with clonic perseveration 2 days after an acute ischemic stroke. We discuss the phenomenology and provide insights on possible pathophysiological mechanisms involved.
Source: Journal of Stroke and Cerebrovascular Diseases - May 17, 2016 Category: Neurology Authors: José Luiz Pedroso, Thiago Cardoso Vale, Marcos Knobel, Rodrigo Meirelles Massaud, Elias Knobel Tags: Case Studies Source Type: research

Detection of symptoms of late complications after stroke in young survivors with active surveillance versus usual care.
CONCLUSIONS: Active surveillance leads to higher rates of early symptom detection of non-motor LCAS in young stroke survivors. Implications for rehabilitation Young stroke survivors frequently have late complications after stroke (LCAS) that impair return to pre-stroke responsibilities. Active surveillance for LCAS symptoms with a semi-structured interview increases detection of non-motor late complications. A bundled approach to screening for LCAS symptoms is pragmatic as a majority of young stroke survivors have at least one symptom but no single symptom is present in all stroke survivors. PMID: 33605166 [PubMed - a...
Source: Disability and Rehabilitation - February 19, 2021 Category: Rehabilitation Authors: Gans SD, Michaels E, Thaler DE, Leung LY Tags: Disabil Rehabil Source Type: research

Detection of symptoms of late complications after stroke in young survivors with active surveillance versus usual care
CONCLUSIONS: Active surveillance leads to higher rates of early symptom detection of non-motor LCAS in young stroke survivors. Implications for rehabilitation Young stroke survivors frequently have late complications after stroke (LCAS) that impair return to pre-stroke responsibilities. Active surveillance for LCAS symptoms with a semi-structured interview increases detection of non-motor late complications. A bundled approach to screening for LCAS symptoms is pragmatic as a majority of young stroke survivors have at least one symptom but no single symptom is present in all stroke survivors.PMID:33605166 | DOI:10.1080/09638288.2021.1883749
Source: Disability and Rehabilitation - February 19, 2021 Category: Rehabilitation Authors: Sarah D Gans Elena Michaels David E Thaler Lester Y Leung Source Type: research

Mental health outcomes in children with acquired dystonia after basal ganglia stroke and associations with cognitive and motor outcomes.
The objective of this study was to explore mental health outcomes in children with basal ganglia stroke and to determine whether children with post-stroke dystonia experience additional mental health difficulties. We also examined associations between mental health, cognitive, and motor outcomes. Participants were 75 children with stroke involving the basal ganglia and/or thalamus (dystonia n = 24, no dystonia n = 51). Results supported the presence of greater levels of anxiety and depression symptoms in children with post-stroke dystonia after stroke relative to those with similar patterns of stroke, but no dystonia. Th...
Source: Child Neuropsychology - January 29, 2020 Category: Child Development Authors: Ledochowski J, Desrocher M, Williams T, Dlamini N, Westmacott R Tags: Child Neuropsychol Source Type: research

Parkinsonism or Other Movement Disorders Presenting as Stroke Mimics.
CONCLUSION: Although rare, parkinsonism or other movement disorders may present as a stroke mimic with activation of a stroke code. Consulting neurologists should clarify the etiology for those patients with acute consciousness disturbance or motor weakness and avoid unnecessary thrombolysis. Key Words: Parkinson disease, parkinsonism, movement disorders, stroke code, thrombolysis. PMID: 28382611 [PubMed - in process]
Source: Acta Neurologica Taiwanica - April 8, 2017 Category: Neurology Tags: Acta Neurol Taiwan Source Type: research

Post stroke hemi-dystonia in children: a neglected area of research
Conclusions Dystonia after CAIS is a common yet insufficiently understood and poorly studied clinical challenge. Studies to improve our understanding of the underlying pathophysiology and consequently the development of instruments for early prediction as well as targeted treatment of dystonia should become a high priority in collaborative childhood stroke research.
Source: Molecular and Cellular Pediatrics - December 11, 2015 Category: Cytology Source Type: research

Deep brain stimulation for movement disorders after stroke: a systematic review of the literature
CONCLUSIONS: This is the first systematic review of DBS for poststroke movement disorders. Overall, most studies to date have been case reports and small series reporting heterogeneous patients and surgical strategies. This review suggests that DBS for movement disorders after a stroke has the potential to be effective and safe for diverse patients, and DBS may be a feasible option to improve function even years after a stroke.PMID:36308482 | DOI:10.3171/2022.8.JNS221334
Source: Journal of Neurosurgery - October 29, 2022 Category: Neurosurgery Authors: Mitch R Paro Michal Dyrda Srinath Ramanan Grant Wadman Stacey-Ann Burke Isabella Cipollone Cory Bosworth Sarah Zurek Patrick B Senatus Source Type: research

Post-Thalamic Stroke Movement Disorders: A Systematic Review
Background: After a stroke, movement disorders are rare manifestations mainly affecting the deep structures of the brain like the basal ganglia (44%) and thalamus (37%), although there have been case studies of movement disorders in strokes affecting the cerebral cortex also.Summary: This review aims to delineate the various movement disorders seen in association with thalamic strokes and tries to identify the location of the nuclei affected in each of the described movement disorders. Cases were identified through a search of PubMed database using different search terms related to post-thalamic stroke movement disorders a...
Source: European Neurology - June 5, 2018 Category: Neurology Source Type: research

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