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Condition: Atrial Fibrillation
Procedure: Dialysis

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Total 370 results found since Jan 2013.

Apixaban for stroke prevention in hemodialysis patients with non-valvular atrial fibrillation
Atrial fibrillation (AF) is a common arrhythmia among patients with kidney failure on maintenance hemodialysis (HD) and is associated with a high incidence of all-cause mortality and stroke in this population.1
Source: Kidney International - April 11, 2023 Category: Urology & Nephrology Authors: Thomas A. Mavrakanas Tags: nephrology digest Source Type: research

Apixaban for stroke prevention in hemodialysis patients with nonvalvular atrial fibrillation
Atrial fibrillation (AF) is a common arrhythmia among patients with kidney failure on maintenance hemodialysis (HD) and is associated with a high incidence of all-cause mortality and stroke in this population.1
Source: Kidney International - April 11, 2023 Category: Urology & Nephrology Authors: Thomas A. Mavrakanas Tags: Nephrology Digest Source Type: research

Can I use DOAC in a patient with renal disease?
Case A 76-year-old man is diagnosed with non-valvular atrial fibrillation. His comorbid conditions are hypertension, diabetes complicated by neuropathy, and chronic kidney disease stage 3. His current medications include metformin, lisinopril, gabapentin, and aspirin. His most recent laboratories showed a creatinine 1.8, creatinine clearance (CrCl) 35 mL/min, hemoglobin 11g/dL, and international normalized ratio 1.0. His congestive heart failure, hypertension, age, diabetes, stroke, vascular disease, and sex (CHADSVASc) score is 4. Which medication should we use to prevent stroke in this patient?  Brief overview of the is...
Source: The Hospitalist - February 3, 2022 Category: Hospital Management Authors: Ronda Whitaker Tags: Renal & Genitourinary Source Type: research

Racial Differences and Outcomes of Strokes in Patients on Hemodialysis: A 10-Year Retrospective Study (P1.081)
CONCLUSIONS: AIS was a common complication in HD patients affecting LOS as well as mortality. African Americans patients were younger compared to Caucasians, who had higher incidence of atrial fibrillation. Overall mortality was high and infections were an independent predictor of mortality in HD patients with stroke. Study Supported by: NoneDisclosure: Dr. Sunbulli has nothing to disclose. Dr. Dhakar has nothing to disclose. Dr. Rajamani has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Sunbulli, M., Dhakar, M., Rajamani, K. Tags: Neuroepidemiology: Cerebrovascular Disease Source Type: research

New XARELTO ® (rivaroxaban) Peripheral Artery Disease (PAD) Data from EXPLORER Clinical Research Program to be Unveiled at American Heart Association (AHA) Scientific Sessions 2020
RARITAN, N.J., November 9, 2020 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced that 10 data presentations will be shared at the virtual American Heart Association (AHA) Scientific Sessions 2020 from November 13-17. Most notably, four new sub-analyses of XARELTO® (rivaroxaban) from the landmark VOYAGER PAD trial, part of the EXPLORER global cardiovascular research program, will be presented, including two live, featured science oral presentations. “We're pleased VOYAGER PAD was selected to be front and center once again at a major medical congress, as there's an urgent need for data in ...
Source: Johnson and Johnson - November 9, 2020 Category: Pharmaceuticals Tags: Innovation Source Type: news

Effectiveness and Safety of Warfarin in Dialysis Patients With Atrial Fibrillation: A Meta-Analysis of Observational Studies
The objective of this study was to assess the effectiveness and safety of warfarin use in patients with AF undergoing dialysis. Three databases PubMed, EMBASE, and OVID were searched from their inception to August 2015. Observational studies which assessed the ischemic stroke or bleeding risk of warfarin use in dialysis patients with AF were included. Two reviewers independently extracted data and assessed methodological quality based on the Newcastle–Ottawa Scale score. Combined hazard ratios (HRs) and 95% confidence intervals (CIs) were calculated using the random-effects model and heterogeneity was assessed based...
Source: Medicine - December 1, 2015 Category: Internal Medicine Tags: Research Article: Meta-Analysis of Observational Studies in Epidemiology Source Type: research

Clinical characteristics and outcomes of dialysis patients with atrial fibrillation: the Fushimi AF Registry
Abstract Atrial fibrillation (AF) is common in dialysis patients. However, clinical characteristics and outcomes of dialysis patients with AF are poorly understood. The Fushimi AF Registry is a community-based prospective survey of AF patients in Japan. Follow-up data were available for 3713 patients with a median follow-up of 2.8 years. We compared clinical characteristics and outcomes between the dialysis group (n = 92; 2.5 %) and others. The dialysis group had more various co-morbidities, with a mean CHADS2 score of 2.5, and the rate of warfarin prescription was 38 %. The annual incidence rates of stroke ...
Source: Heart and Vessels - March 14, 2016 Category: Cardiology Source Type: research

Cardiologists' and nephrologists' management of atrial fibrillation in hemodialysis patients 
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CONCLUSION: Cardiologists were more likely to prescribe anticoagulant therapy for AF in the HD population compared to nephrologists, regardless of patient stroke or bleeding risk.
. PMID: 31496513 [PubMed - as supplied by publisher]
Source: Clinical Nephrology - September 8, 2019 Category: Urology & Nephrology Authors: Marcus L, Mackeigan L, Leblanc K, Orlov D, Mitsakakis N, Austin Z, Jassal SV, Battistella M Tags: Clin Nephrol Source Type: research

Left Atrial Appendage Closure During Coronary Bypass Surgery in Patients on Hemodialysis
CONCLUSIONS: Concomitant LAA closure during CABG can reduce the risk of death and stroke in ESRD-HD patients with normal sinus rhythm.PMID:36928272 | DOI:10.1253/circj.CJ-22-0573
Source: Circulation Journal - March 17, 2023 Category: Cardiology Authors: Daisuke Endo Takeshi Kinoshita Jiyoung Lee Yoichiro Machida Kosuke Nishida Yuichiro Sato Taira Yamamoto Minoru Tabata Source Type: research

Efficacy and safety of direct oral anticoagulants vs vitamin K antagonists in patients with atrial fibrillation and end-stage renal disease on hemodialysis: A systematic review and meta-analysis
CONCLUSIONS: Among AF patients with ESRD on chronic hemodialysis, the risk of ischemic stroke, ischemic stroke or systemic embolism, minor bleeding, major bleeding, and all-cause mortality is similar in patients treated with DOACs compared to VKAs. Given that the meta-analysis of RCTs on gastrointestinal bleeding did not confirm the results of the meta-analysis of the observational studies, it cannot be concluded that gastrointestinal bleeding is lower among DOAC-treated patients.PROTOCOL REGISTRATION: PROSPERO CRD42023391966.PMID:37648582 | DOI:10.1016/j.ejim.2023.08.020
Source: European Journal of Internal Medicine - August 30, 2023 Category: Internal Medicine Authors: Ioannis Kyriakoulis Anastasia Adamou Iliana Stamatiou David Dimitris Chlorogiannis Ioannis Kardoutsos Despoina Koukousaki George Ntaios Source Type: research

Valvular calcification upon initiating dialysis predict the appearance of cardiovascular events in patient evolution.
CONCLUSIONS: The prevalence of VC at the commencement of dialysis is very high and its presence is an independent predictor of event and cardiovascular mortality presentation in the course of follow-up. PMID: 26300509 [PubMed - as supplied by publisher]
Source: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia - August 25, 2015 Category: Urology & Nephrology Tags: Nefrologia Source Type: research