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Condition: Atrial Fibrillation
Procedure: CT Scan

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Total 484 results found since Jan 2013.

Evidence-Based Minireview: Mortality and thrombosis in patients receiving prothrombin complex concentrates or andexanet alfa for the management of direct oral factor Xa inhibitor-associated major bleeding.
Authors: Kimpton M, Siegal DM Abstract A 77-year-old man with atrial fibrillation and a CHA2DS2Vasc score of 6 for hypertension, age, diabetes, and previous stroke is brought to the emergency department with decreased level of consciousness. He is anticoagulated with rivaroxaban (a direct oral factor Xa inhibitor [FXaI]) and received his last dose about 4 hours before presentation. Urgent computed tomography of the head shows intracerebral hemorrhage. Because of his previous stroke, the patient's family is concerned about treating the bleed with pharmacological agents that may increase the risk of stroke. What are ...
Source: Hematology ASH Education Program - December 7, 2019 Category: Hematology Tags: Hematology Am Soc Hematol Educ Program Source Type: research

Vitamin K Antagonist Use and Risk for Intracranial Carotid Artery Calcification in Patients With Intracerebral Hemorrhage
Conclusions: Our findings do not support VKA use as an independent risk factor for higher ICAC degree in patients with ICH. We could not confirm the concerns about VKA use and intracranial carotid vascular calcification. We suggest further research in other cohorts with VKA users such as patients with ischemic stroke and atrial fibrillation.
Source: Frontiers in Neurology - December 19, 2019 Category: Neurology Source Type: research

Anticoagulant management by low-dose of low molecular weight heparin in patients with nonvalvular atrial fibrillation following hemorrhagic transformation and complicated with venous thrombosis: Five case reports and literature review
For patients with nonvalvular atrial fibrillation (NVAF) following hemorrhagic infarction (HI)/hemorrhage transformation (HT) and complicated with venous thrombosis, the management of anticoagulation is controversial. Our study intends to explore the safety and effectiveness of using low-dose of low molecular weight heparin (LMWH) to treat NVAF patients with HI (or HT) and complicated with venous thrombosis. Between January 2018 and January 2019, NVAF related acute ischemic stroke patients with HT/HI, hospitalized in the department of neurology or rehabilitation in our hospital, are enrolled retrospectively. Among them,...
Source: Medicine - February 19, 2021 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Relations between left atrial appendage contrast retention and thromboembolic risk in patients with atrial fibrillation
This study was designed to assess the relations between LAA contrast retention and thrombogenesis risk of the LAA in patients with non-valvular atrial fibrillation. A total of 132 consecutive patients who underwent LAAO were enrolled. The data collected from computed tomography (CT), transthoracic echocardiography (TTE), transesophageal echocardiography (TEE) and blood samples were analyzed. Univariate and multivariate logistic regression models were constructed to assess the association between CR, left atrial appendage thrombus (LAAT) and other factors. Contrast retention was observed in 33 patients, accounting for 25% o...
Source: Journal of Thrombosis and Thrombolysis - June 15, 2021 Category: Hematology Source Type: research

Incorporating coronary calcification by computed tomography into CHA2DS2-VASc score: impact on cardiovascular outcomes in patients with atrial fibrillation
ConclusionCoronary artery calcification is prevalent in AF patients undergoing PVI and independently associated stroke, death and MACE even when adjusted for traditional CHA2DS2-VASc score. Adding CAC as vascular component to the CHA2DS2-VASc score requires further research as it potentially modified the anticoagulation management in 20% of our AF cohort.
Source: Europace - February 15, 2021 Category: Cardiology Source Type: research

E-023 Predictors of outcomes in tandem anterior circulation occlusions following mechanical thrombectomy
In this study, we present outcomes of patients undergoing tandem mechanical thrombectomy. We demonstrate that stenting is associated with improved final reperfusion, but increased odds of asymptomatic ICH. Additional clinical trials should be performed to optimize the procedure and improve patient outcomes.Disclosures J. Catapano: None. D. Farhadi: None. A. Naik: None. S. Koester: None. E. Winkler: None. V. Srinivasan: None. K. Karahalios: None. J. Rulney: None. S. Desai: None. A. Jadhav: None. F. Albuquerque: None. A. Ducruet: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Catapano, J., Farhadi, D., Naik, A., Koester, S., Winkler, E., Srinivasan, V., Karahalios, K., Rulney, J., Desai, S., Jadhav, A., Albuquerque, F., Ducruet, A. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

Automatic Segmentation of the Left Atrium from Computed Tomography Angiography Images
Ann Biomed Eng. 2023 Mar 8. doi: 10.1007/s10439-023-03170-9. Online ahead of print.ABSTRACTThe left atrial appendage (LAA) causes 91% of thrombi in atrial fibrillation patients, a potential harbinger of stroke. Leveraging computed tomography angiography (CTA) images, radiologists interpret the left atrium (LA) and LAA geometries to stratify stroke risk. Nevertheless, accurate LA segmentation remains a time-consuming task with high inter-observer variability. Binary masks of the LA and their corresponding CTA images were used to train and test a 3D U-Net to automate LA segmentation. One model was trained using the entire un...
Source: Annals of Biomedical Engineering - March 8, 2023 Category: Biomedical Engineering Authors: Amaan Kazi Sage Betko Anish Salvi Prahlad G Menon Source Type: research

A cloudy story: Guillain–Barré syndrome concealed by a spontaneous intracerebral haemorrhage
We present a case of Guillain–Barré syndrome (GBS), probably associated with influenza vaccine, occurring in a patient some days after a spontaneous haemorrhagic stroke. A 79-year-old woman was admitted to the neurosurgery department after a sudden severe headache, dizziness, and progressive generalised weakness. She had a history of hypertension and paroxysmal atrial fibrillation in dicumarolic therapy. Head CT scan showed a haemorrhagic stroke in left cerebellum, with compression on the fourth ventricle.
Source: Clinical Neurophysiology - October 22, 2012 Category: Neuroscience Authors: V. Mantero, L. De Toni Franceschini, L. Abate, F. Villa, A. Patruno, S. Jann, G. Citerio Tags: Letters to the Editor Source Type: research

Computed Tomography Imaging for Left Atrial Appendage Closure: A Review and Pictorial Essay
Cardioembolic stroke is an important complication of atrial fibrillation (AF). The thrombus responsible for this arises from the left atrial appendage (LAA) in>90% of cases, providing the rationale for device-based LAA closure as a means of thromboprophylaxis. While oral anticoagulant therapy remains the mainstay for reducing the risk of stroke in patients with AF, an increasing number of patients, particularly those ineligible for conventional pharmacotherapy, are being offered percutaneous left atrial appendage closure.
Source: Journal of Cardiovascular Computed Tomography - January 24, 2015 Category: Radiology Authors: Tevfik F. Ismail, Sandeep Panikker, Vias Markides, John P. Foran, Simon Padley, Michael B. Rubens, Tom Wong, Edward Nicol Source Type: research

CT imaging for left atrial appendage closure: A review and pictorial essay
Cardioembolic stroke is an important complication of atrial fibrillation. The thrombus responsible for this arises from the left atrial appendage (LAA) in>90% of cases, providing the rationale for device-based LAA closure as a means of thromboprophylaxis. Although oral anticoagulant therapy remains the mainstay for reducing the risk of stroke in patients with atrial fibrillation, an increasing number of patients, particularly those ineligible for conventional pharmacotherapy, are being offered percutaneous left atrial appendage closure.
Source: Journal of Cardiovascular Computed Tomography - January 24, 2015 Category: Radiology Authors: Tevfik Fehmi Ismail, Sandeep Panikker, Vias Markides, John P. Foran, Simon Padley, Michael B. Rubens, Tom Wong, Edward Nicol Tags: Pictorial Essay Source Type: research

Does Left Atrial Appendage Morphology Influence Left Atrial Appendage Flow Velocity?
CONCLUSIONS: The NCW-type LAA and higher BNP were associated with lower LAAFV. One reason for the frequent cardiogenic stroke in patients with the NCW-type LAA may be the lower LAAFV. PMID: 25959433 [PubMed - as supplied by publisher]
Source: Circulation Journal - May 9, 2015 Category: Cardiology Authors: Kishima H, Mine T, Ashida K, Sugahara M, Kodani T, Masuyama T Tags: Circ J Source Type: research

Correlation between left atrial appendage morphology and flow velocity in patients with paroxysmal atrial fibrillation
Conclusion LAA morphology is a significant determinant of LAAFV, suggesting an underlying mechanism for the association between LAA morphology and embolic events.
Source: European Journal of Echocardiography - December 18, 2015 Category: Cardiology Authors: Fukushima, K., Fukushima, N., Kato, K., Ejima, K., Sato, H., Fukushima, K., Saito, C., Hayashi, K., Arai, K., Manaka, T., Ashihara, K., Shoda, M., Hagiwara, N. Tags: ORIGINAL ARTICLES Source Type: research