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Long-term changes in coronary physiology after aortic valve replacement
Conclusions: CFR in the LAD increased significantly at follow-up although global hyperaemic flow and minimal microvascular resistance remained unchanged. Thus, a decrease in resting flow was the cause of CFR improvement. CFR improvement was associated with reduction in LVSW.PMID:36239118 | DOI:10.4244/EIJ-D-22-00621
Source: EuroIntervention - October 14, 2022 Category: Cardiovascular & Thoracic Surgery Authors: Muhammad Sabbah Niels T Olsen Lene Holmvang Hans-Henrik Tilsted Frants Pedersen Francis Richard Joshi Rikke S ørensen Reza Jabbari Ketina Arslani Lars Sondergaard Thomas Engstr øm Jacob Thomsen L ønborg Source Type: research

Spontaneous Spinal Epidural Hematoma in an Adult Patient with Complex Congenital Heart Disease
We report the case of a 27-year-old man who developed sudden upper back pain with no specific precipitant. Five days later, he visited our emergency department complaining of weakness in both lower limbs and dysuria. He had a history of intracardiac repair and a Blalock-Park procedure for an interrupted aortic arch and ventricular septal defect in infancy. Additionally, he had undergone an aortic root dilatation and aortic valve replacement at the age of 10 because of progression of aortic and supra-aortic stenosis and had received chronic anticoagulation and antiplatelet therapy with warfarin and aspirin, respectively. An...
Source: International Heart Journal - July 8, 2021 Category: Cardiology Authors: Toshinobu Ifuku Toshihiro Nishiguchi Source Type: research

Prevalence and Risk Factors of Silent Brain Infarction in Patients with Aortic Stenosis
Conclusion: These findings indicate that AS is associated with a high prevalence of SBI, and that the CHA2DS2-VASc score and eGFR are useful for risk stratification.Cerebrovasc Dis Extra 2020;10:116 –123
Source: Cerebrovascular Diseases Extra - October 8, 2020 Category: Neurology Source Type: research

Non-Invasive Quantification of Ventricular Contractility, Arterial Elastic Function and Ventriculo-Arterial Coupling from a Single Diagnostic Encounter Using Simultaneous Arterial Tonometry and Magnetic Resonance Imaging
ConclusionNon-invasive assessment of LV pressure –volume and aortic pressure-flow relationships are both feasible and reproducible using simultaneous AT and CMRI. Methods permit assessment of load independent LV contractility, arterial function and LV/arterial coupling from a single non-invasive diagnostic encounter.
Source: Cardiovascular Engineering and Technology - April 19, 2020 Category: Cardiology Source Type: research

Randomised comparison of a  balloon-expandable and self-expandable valve with quantitative assessment of aortic regurgitation using magnetic resonance imaging.
CONCLUSIONS: The use of the latest generation of BEV was associated with less AR as quantitatively assessed by MRI. Although the use of MRI to quantify AR is not feasible in daily clinical practice, it should be considered as a surrogate endpoint for clinical outcomes in comparative studies of valves for TAVI. ClinicalTrials.gov number NCT01982032. PMID: 32246266 [PubMed - as supplied by publisher]
Source: Netherlands Heart Journal - April 2, 2020 Category: Cardiology Authors: Kooistra NHM, Abawi M, Voskuil M, Urgel K, Samim M, Nijhoff F, Nathoe HM, Doevendans PAFM, Chamuleau SAJ, Leenders GEH, Leiner T, Abrahams AC, van der Worp HB, Agostoni P, Stella PR Tags: Neth Heart J Source Type: research

Light ‐chain and transthyretin cardiac amyloidosis in severe aortic stenosis: prevalence, screening possibilities, and outcome
ConclusionBoth TTR ‐ and AL‐CA can accompany severe AS. Parameters solely based on ECG and echocardiography allow for the identification of the majority of CA‐AS. In the present cohort, CA did not significantly worsen prognosis 15.3 months after TAVR.
Source: European Journal of Heart Failure - March 4, 2020 Category: Cardiology Authors: Christian Nitsche, Stefan Aschauer, Andreas A. Kammerlander, Matthias Schneider, Thomas Poschner, Franz Duca, Christina Binder, Matthias Koschutnik, Julian Stiftinger, Georg Goliasch, Jolanta Siller ‐Matula, Max‐Paul Winter, Anahit Anvari� Tags: Research Article Source Type: research

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