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Condition: Alcoholism
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Total 522 results found since Jan 2013.
An unusual case of a triple suicide pact at the time of the COVID-19 pandemic
J Forensic Sci. 2023 Aug 10. doi: 10.1111/1556-4029.15358. Online ahead of print.ABSTRACTIn December 2020, the World Health Organization (WHO) declared SARS-CoV2 a global pandemic. Home confinement, low social contacts, and fear of virus transmission played a major role as risk factors for suicides during the following period. Suicide pacts, in particular, showed a different pattern. A rare case of a triple suicide pact among members of the same family nucleus is presented. The victims were an elderly, severely ill woman and her adult children (a son and daughter), linked by a morbid relationship. The last time the family ...
Source: Journal of Forensic Sciences - August 11, 2023 Category: Forensic Medicine Authors: Silvia Raddi Ilaria Tarozzi Matteo Cecchetti Silvio Chericoni Lorenzo Franceschetti Valentina Bugelli Source Type: research
The association between income inequality and adolescent body mass index: findings from the COMPASS study (2016-2019)
CONCLUSION: The association between income inequality and BMI, being overweight, or having obesity appears to be non-linear. Public health units and schools may benefit from incorporating upstream factors such as income inequality into their interventions attempting to promote healthy weights.PMID:37526917 | DOI:10.17269/s41997-023-00798-x
Source: Canadian Journal of Public Health - August 1, 2023 Category: International Medicine & Public Health Authors: Stephen Hunter Edwina Veerasingam Tracie A Barnett Karen A Patte Scott T Leatherdale Roman Pabayo Source Type: research
Fight Aging! Newsletter, July 31st 2023
In conclusion, an SBP level below 130 mmHg was found to be associated with longevity among older women. The longer SBP was controlled at a level between 110 and 130 mmHg, the higher the survival probability to age 90. Preventing age-related rises in SBP and increasing the time with controlled BP levels constitute important measures for achieving longevity.
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Source: Fight Aging! - July 30, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, June 12th 2023
In this study, we investigated the effect of NXP032 on neurovascular stabilization through the changes of PECAM-1, PDGFR-β, ZO-1, laminin, and glial cells involved in maintaining the integrity of the blood-brain barrier (BBB) in aged mice. NXP032 was orally administered daily for 8 weeks. Compared to young mice and NXP032-treated mice, 20-month-old mice displayed cognitive impairments in Y-maze and passive avoidance tests. NXP032 treatment contributed to reducing the BBB damage by attenuating the fragmentation of microvessels and reducing PDGFR-β, ZO-1, and laminin expression, thereby mitigating astrocytes and microglia ...
Source: Fight Aging! - June 11, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Alcohol consumption and risks of more than 200 diseases in Chinese men
Nat Med. 2023 Jun 8. doi: 10.1038/s41591-023-02383-8. Online ahead of print.ABSTRACTAlcohol consumption accounts for ~3 million annual deaths worldwide, but uncertainty persists about its relationships with many diseases. We investigated the associations of alcohol consumption with 207 diseases in the 12-year China Kadoorie Biobank of >512,000 adults (41% men), including 168,050 genotyped for ALDH2- rs671 and ADH1B- rs1229984 , with >1.1 million ICD-10 coded hospitalized events. At baseline, 33% of men drank alcohol regularly. Among men, alcohol intake was positively associated with 61 diseases, including 33 not defi...
Source: Cancer Control - June 8, 2023 Category: Cancer & Oncology Authors: Pek Kei Im Neil Wright Ling Yang Ka Hung Chan Yiping Chen Yu Guo Huaidong Du Xiaoming Yang Daniel Avery Shaojie Wang Canqing Yu Jun Lv Robert Clarke Junshi Chen Rory Collins Robin G Walters Richard Peto Liming Li Zhengming Chen Iona Y Millwood China Kadoo Source Type: research
Multi-domain prognostic models used in middle-aged adults without known cognitive impairment for predicting subsequent dementia
CONCLUSIONS: We identified 14 unique multi-domain prognostic models used in middle-aged adults for predicting subsequent dementia. Diabetes, hypertension, obesity, and smoking were the most common modifiable risk factors used as predictors in the models. We performed meta-analyses of C-statistics for one model (CAIDE), but the summary values were unreliable. Owing to lack of data, we were unable to meta-analyse the calibration measures of CAIDE. This review highlights the need for further robust external validations of multi-domain prognostic models for predicting future risk of dementia in middle-aged adults.PMID:37265424...
Source: Cochrane Database of Systematic Reviews - June 2, 2023 Category: General Medicine Authors: Gopisankar Mohanannair Geethadevi Terry J Quinn Johnson George Kaarin J Anstey J Simon Bell Muhammad Rehan Sarwar Amanda J Cross Source Type: research
Psychosocial and pharmacologic interventions to reduce harmful alcohol use in low- and middle-income countries
CONCLUSIONS: In LMICs there is low-certainty evidence supporting the efficacy of combined psychosocial and pharmacologic interventions on reducing harmful alcohol use relative to psychosocial interventions alone. There is insufficient evidence to determine the efficacy of pharmacologic or psychosocial interventions on reducing harmful alcohol use largely due to the substantial heterogeneity in outcomes, comparisons, and interventions that precluded pooling of these data in meta-analyses. The majority of studies are brief interventions, primarily among men, and using measures that have not been validated in the target popul...
Source: Cochrane Database of Systematic Reviews - May 9, 2023 Category: General Medicine Authors: M Claire Greene Jeremy Kane Michelle Alto Ali Giusto Kathryn Lovero Melissa Stockton Jasmine McClendon Terriann Nicholson Milton L Wainberg Renee M Johnson Wietse Anton Tol Source Type: research
Reducing Prenatal Alcohol Exposure and the Incidence of FASD: Is the Past Prologue?
CONCLUSIONS: Case management and home visits did not appear to have strong current empirical support. Study limitations included small sample sizes and no comparison groups, whereas larger efforts did not demonstrate definitive advantages to justify this intensive approach. The studies of preconception efforts, all based on the Project CHOICES approach, had similar outcomes, with the reduction in AEP risk largely due to improved contraception in women of childbearing age who were sexually active and drank alcohol but were not pregnant. It is unknown whether these women refrained from alcohol use when they became pregnant. ...
Source: Alcohol Research - April 28, 2023 Category: Addiction Authors: Grace Chang Source Type: research
