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Enhanced Detection of Edema in Malignant Anterior Circulation Stroke (EDEMA) Score Brief Report
Conclusions—The EDEMA score identifies patients at high risk for potentially lethal malignant edema. Although it requires external validation, this scale could help expedite triage decisions in this patient population.
Source: Stroke - June 26, 2017 Category: Neurology Authors: Charlene Jennifer Ong, Jeffrey Gluckstein, Osvaldo Laurido-Soto, Yan Yan, Rajat Dhar, Jin-Moo Lee Tags: Clinical Studies, Cerebrovascular Disease/Stroke, Ischemic Stroke, Thrombosis Brief Reports Source Type: research

Vascular Territories of Ischemic Stroke in Associated Takotsubo Cardiomyopathy (P1.221)
Conclusions: TC is a reversible cardiomyopathy that has an association with ischemic stroke. This condition can notably be both the cause and effect of stroke. Ischemic stroke of the left middle cerebral artery appears to be the most prevalent. In female patients suffering from middle cerebral artery distribution ischemic stroke and cardiac dysfunction, TC should be considered.Disclosure: Dr. Zia has nothing to disclose. Dr. Silliman has received research support from Genzyme Corporation, Biogen Idec, and Novartis.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Zia, A., Silliman, S. Tags: Cardiac Mechanisms and Complications of Stroke Source Type: research

Rapidly improving neurological deficit of stroke; case series in Academic institute, KAUH, Jeddah (P4.283)
Conclusions:Rapidly improving patient represent a challenge to whether tPA should be given. However, the good outcome with thrombolytic therapy observed in our study, will hopfuly support the decision to treat.Study Supported by: nonDisclosure: Dr. khoja has nothing to disclose. Dr. Alshaer has nothing to disclose. Dr. al-Turkistani has nothing to disclose. Dr. Al-Mekhalfi has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: khoja, a., Al-Shaer, D., al-Turkistani, a., Al-Mekhalfi, M. Tags: Thrombolysis and Acute Evaluation in Ischemic Stroke Source Type: research

Identifying Gaps and Missed Opportunities for Intravenous Thrombolytic Treatment of Inpatient Stroke
Conclusion: In our study, one in three ISC were true strokes. IVT treatment rates were low with a MTO of 1 in 6 IVT-eligible patients. The most common reason for not treating was NIHSS ≤4. Knowing predictors of true stroke and the common barriers to IVT treatment can help narrow this treatment gap.
Source: Frontiers in Neurology - February 25, 2020 Category: Neurology Source Type: research

Safety of Low Dose Intravenous Cangrelor in Acute Ischemic Stroke: A Case Series
Conclusion: Low dose intravenous cangrelor is similar in safety and efficacy to oral antiplatelets in acute ischemic stroke in a small case series. Larger prospective studies on the efficacy, safety, and effect on procedure times of intravenous cangrelor in neurointervention are warranted.
Source: Frontiers in Neurology - June 4, 2021 Category: Neurology Source Type: research

Simple prediction model for unfavorable outcome in ischemic stroke after intravenous thrombolytic therapy
Conclusion An NIHSS> 12 on arrival, presence of HAS and age> 70 years were predictors of unfavorable outcome at three months in patients with acute ischemic stroke treated with IVT.RESUMO Objetivo Desenvolver um modelo para predizer desfecho desfavor ável em pacientes com acidente vascular cerebral isquêmico (AVCi) agudo tratados com terapia trombolítica intravenosa (TTI), baseado em variáveis simples presentes à admissão. Métodos Análise retrospectiva de casos de AVCi tratados com TTI em um hospital no Rio de Janeiro. Variáveis clín icas e radiográficas foram selecionadas para análise. Foi utilizada regr...
Source: Arquivos de Neuro-Psiquiatria - December 15, 2016 Category: Neurology Source Type: research

Repeated Mechanical Thrombectomy in the Same Intracranial Artery Segment
We report a patient with an important scenario that may arise in the management of an acute ischemic stroke: the need for a repeated mechanical thrombectomy in the same intracranial artery segment. The patient had a history of atrial fibrillation and a mechanical mitral valve replacement. In her first stroke, she had an occlusion of the proximal segment of the right middle cerebral artery; 58 days later, she presented with an occlusion in the same segment of that cerebral artery. In both instances, the thrombus was extracted by a stent retriever with good clinical and radiographic results.
Source: Journal of Stroke and Cerebrovascular Diseases - June 30, 2017 Category: Neurology Authors: Herbert Tejada Meza, Maria Rosario Barrena Caballo, Santiago Guelbenzu Morte, Roberto Mart ínez García, Javier Marta Moreno Tags: Case Studies Source Type: research

Pediatric Cortical Vein Thrombosis: Frequency and Association With Venous Infarction Brief Reports
Conclusions— In our cohort, CVT was significantly associated with seizures at presentation, hemorrhage and restricted diffusion on acute imaging, as well as neurological disability and venous infarction at follow-up. Involvement of cortical veins in cerebral sinovenous thrombosis is associated with an increased risk of infarction and adverse outcome in children.
Source: Stroke - February 22, 2016 Category: Neurology Authors: Ritchey, Z., Hollatz, A. L., Weitzenkamp, D., Fenton, L. Z., Maxwell, E. C., Bernard, T. J., Stence, N. V. Tags: Pediatrics, Cerebrovascular Disease/Stroke Brief Reports Source Type: research

Asymptomatic Carotid Stenosis Is Associated With Circadian and Other Variability in Embolus Detection
Conclusions: Embolism associated with asymptomatic carotid stenosis shows circadian variation with highest rates 4–6 h before midday. This corresponds with peak circadian incidence of stroke and other vascular complications. These and ASED Study results show that monitoring frequency, duration, and time of day are important in ES detection. Introduction Transcranial Doppler (TCD) detected microembolism in the ipsilateral middle cerebral artery (MCA) may help stratify the risk of stroke and other arterial disease complications in persons with advanced (≥60%) asymptomatic carotid stenosis. If so, this t...
Source: Frontiers in Neurology - April 15, 2019 Category: Neurology Source Type: research

Single-Center Description of Therapeutic Anticoagulation Practices and Outcomes in Large Hemispheric Infarctions
Discussion Although radiographic HT is common among patients with LHI, it does not always portend symptomatic clinical deterioration. Further research regarding AC timing and safety is necessary.
Source: Neurology Clinical Practice - December 13, 2022 Category: Neurology Authors: Breit, H., Sterenstein, A., Abburi, N., Song, S., John, S., Da Silva, I., Koffman, L. Tags: Research Article Source Type: research

Functional Outcome After Perinatal Cerebral Sinovenous Thrombosis: A Prospective Cohort Study (S42.006)
CONCLUSIONS: We found a high rate of neurological morbidity and seizure burden after perinatal CSVT which significantly impacted achievement of age-appropriate developmental milestones and function. Measures and predictors of functional outcome following perinatal CSVT need further exploration.Disclosure: Dr. Billinghurst has nothing to disclose. Dr. Uohara has nothing to disclose. Dr. Licht has nothing to disclose. Dr. Ichord has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Billinghurst, L., Uohara, M., Licht, D., Ichord, R. Tags: Child Neurology I Source Type: research

Contrast induced encephalopathy mimicking reperfusion injury (P3.285)
Conclusions:Diagnostic or therapeutic angiography is frequently performed for acute ischemic or hemorrhagic stroke. Clinicians should be aware of contrast induced encephalopathy and consider it in cases of neurologic deterioration after angiography in order to initiate appropriate treatment and avoid unnecessary invasive tests.Disclosure: Dr. Bakradze has nothing to disclose. Dr. Pasquale has nothing to disclose. Dr. Kirchoff-Torres has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Bakradze, E., Pasquale, D., Kirchoff-Torres, K. Tags: Cerebrovascular Disease Case Reports II Source Type: research

Compliance with Early Use of Prophylactic Anticoagulation after Intracerebral Hemorrhage (P02.047)
CONCLUSIONS: Despite implementation of guideline-based practice, 12% of our ICH patients did not receive early prophylactic anticoagulation despite a clear lack of contraindication. Continued quality improvement towards guideline-driven care may be enhanced by the use of checklists to overcome individual physician biases and preferences.Disclosure: Dr. Hoang has nothing to disclose. Dr. John has nothing to disclose. Dr. Garg has received research support from the AHA. Dr. Busl has nothing to disclose. Dr. Temes has nothing to disclose. Dr. Bleck has nothing to disclose. Dr. Prabhakaran has nothing to disclose.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Hoang, T., John, S., Garg, R., Busl, K., Temes, R., Bleck, T., Prabhakaran, S. Tags: P02 Cerebrovascular Disease II Source Type: research

Pediatric cavernous sinus thrombosis: A case series and review of the literature
Conclusion: Our case series demonstrates low morbidity and mortality with early, aggressive surgical, antimicrobial, and anticoagulation therapies. Although anticoagulation and surgery were not associated with significantly different outcomes, more study is needed.
Source: Neurology - August 31, 2015 Category: Neurology Authors: Smith, D. M., Vossough, A., Vorona, G. A., Beslow, L. A., Ichord, R. N., Licht, D. J. Tags: Childhood stroke, Secondary headache disorders, Pediatric headache, All Imaging, Cerebral venous thrombosis ARTICLE Source Type: research

Spinal cord injury misdiagnosed as cerebral infarction and given thrombolytic therapy: A case report
【Background】Spinal Cord Injury Without Radiographic Abnormality (SCIWORA) covers a broad spectrum of neurological deficits, which can be confused with cerebral infarction when patients present with hemiparesis and a history of minor injury.
Source: Journal of Stroke and Cerebrovascular Diseases - March 18, 2017 Category: Neurology Authors: Jie Yang, Jing Hang, Junshan Zhou, Yingdong Zhang Source Type: research

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