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Specialty: Allergy & Immunology
Condition: Stroke
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Total 746 results found since Jan 2013.
Microbiota, diet and the gut-brain axis in multiple sclerosis and acute stroke
This article is protected by copyright. All rights reserved.PMID:37470461 | DOI:10.1002/eji.202250229
Source: European Journal of Immunology - July 20, 2023 Category: Allergy & Immunology Authors: Laura Diaz-Marugan Johan B Kantsj ö Andrina Rutsch Francesca Ronchi Source Type: research
Association Between Inflammatory Burden Index and Unfavorable Prognosis After Endovascular Thrombectomy in Acute Ischemic Stroke
Source: Journal of Inflammation Research - July 19, 2023 Category: Allergy & Immunology Tags: Journal of Inflammation Research Source Type: research
Macrophage and monocyte subsets in response to ischemic stroke
This article is protected by copyright. All rights reserved.PMID:37467166 | DOI:10.1002/eji.202250233
Source: European Journal of Immunology - July 19, 2023 Category: Allergy & Immunology Authors: Nelli Blank-Stein Elvira Mass Source Type: research
COVID, complement, and the brain
The brains of COVID-19 patients are affected by the SARS-CoV-2 virus, and these effects may contribute to several COVID-19 sequelae, including cognitive dysfunction (termed “long COVID” by some researchers). Recent advances concerning the role of neuroinflammation and the consequences for brain function are reviewed in this manuscript. Studies have shown that respiratory SARS-CoV-2 infection in mice and humans is associated with selective microglial reactivity in the white matter, persistently impaired hippocampal neurogenesis, a decrease in the number of oligodendrocytes, and myelin loss. Brain MRI studies have reveal...
Source: Frontiers in Immunology - July 18, 2023 Category: Allergy & Immunology Source Type: research
Kidney function and cardiovascular diseases: a large-scale observational and Mendelian randomization study
ConclusionOur study provides evidence for causal effects of CVDs on kidney function. However, the evidence to support the causal effects of kidney function on CVDs is currently insufficient. Further mechanistic studies are required to determine the causality.
Source: Frontiers in Immunology - July 17, 2023 Category: Allergy & Immunology Source Type: research
TNF- α evokes blood-brain barrier dysfunction through activation of Rho-kinase and neurokinin 1 receptor
In conclusion, specific inhibition of Rho kinase in cerebrovascular conditions, accompanied by excessive release of pro-inflammatory cytokine TNF-α, helps preserve endothelial cell morphology and inter-endothelial cell barrier formation and may serve as an important therapeutic target.PMID:37454559 | DOI:10.1016/j.imbio.2023.152706
Source: Immunobiology - July 16, 2023 Category: Allergy & Immunology Authors: Xin Gao Ulvi Bayraktutan Source Type: research
Pharmacological Upregulation of Microglial Lipid Droplet Alleviates Neuroinflammation and Acute Ischemic Brain Injury
In this study, we observed increased LDs accumulation in microglia at the acute stage of ischemic stroke by immunofluorescence and flow cytometry. Transcriptomic analysis indicated that microglia accumulated with LDs were associated with inflammation and phagocytosis. Both inflammatory activation and phagocytosis of tissue debris in microglia could contribute to LDs formation. Moreover, through specific LDs depletion and overload experiments by pharmacological approaches, we proposed that LDs was critical for the maintenance of anti-inflammatory properties of microglia. Furthermore, Atglistatin, a specific adipose triglyce...
Source: Inflammation - July 14, 2023 Category: Allergy & Immunology Source Type: research
Increased Serum Levels of IL-1 β after Ischemic Stroke are Inversely Associated with Vitamin D
CONCLUSION: Ischemic stroke correlates positively with IL-1β and negatively with VitD levels. The speculated role of VitD deficiency in the evolution and severity of stroke may be justified by its role in the modification of inflammation.PMID:37431715 | DOI:10.22034/iji.2023.96384.2432
Source: Iranian Journal of Immunology - July 11, 2023 Category: Allergy & Immunology Authors: Mahnaz Bayat Niloufar Razavi Moosavi Najmeh Karimi Moosa Rahimi Afshin Borhani-Haghighi Source Type: research
The impact of fingolimod on Treg function in brain ischaemia
In conclusion, fingolimod seems to improve the suppressive function of Treg post-stroke while also increasing the resistance of CD4+ effector cells to this suppression. Fingolimod's capacity to increase both effector and regulatory functions may explain the lack of consistent improvement in functional recovery in experimental brain ischaemia.PMID:37366289 | DOI:10.1002/eji.202350370
Source: European Journal of Immunology - June 27, 2023 Category: Allergy & Immunology Authors: Kyle Malone Jennifer A Shearer Christian Waeber Anne C Moore Source Type: research
Identification of cell death-related biomarkers and immune infiltration in ischemic stroke between male and female patients
ConclusionThese findings contribute to a better knowledge of immune cell infiltration and their corresponding molecular mechanisms of cell death and offer distinct clinically relevant biological targets for IS patients of different genders.
Source: Frontiers in Immunology - June 26, 2023 Category: Allergy & Immunology Source Type: research
Ischemic stroke-related gene expression profiles across species: a meta-analysis
Stroke patients are often left with permanent disabilities with no regenerative treatment options. Unbiased RNA sequencing studies decoding the transcriptional signature of stroked tissue hold promise to ident...
Source: Journal of Inflammation - June 19, 2023 Category: Allergy & Immunology Authors: Ruslan Rust Tags: Brief Report Source Type: research
