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Specialty: Cardiology
Condition: Stroke

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Total 25838 results found since Jan 2013.

Intrapulmonary Shunt Is a Potentially Unrecognized Cause of Ischemic Stroke and Transient Ischemic Attack
Background: Ischemic stroke is a major cause of mortality and disability. Transient ischemic attack (TIA) is a harbinger of stroke. The etiology of stroke in as many as 40% of patients remains undetermined after extensive evaluation. It was hypothesized that intrapulmonary shunt is a potential facilitator of cerebrovascular accident (CVA) or TIA.Methods: Patients undergoing clinically indicated transesophageal echocardiography were prospectively enrolled. Comprehensive multiplane transesophageal echocardiographic imaging was performed and saline contrast done to assess for intrapulmonary shunt and patent foramen ovale.Resu...
Source: Journal of the American Society of Echocardiography - May 13, 2013 Category: Cardiology Authors: Mohannad Y. Abushora, Nirmanmoh Bhatia, Ziad Alnabki, Mohan Shenoy, Motaz Alshaher, Marcus F. Stoddard Tags: Stroke, TIA, and Intrapulmonary Shunting Source Type: research

Trials to Improve Blood Pressure Through Adherence to Antihypertensives in Stroke/TIA: Systematic Review and Meta-Analysis Stroke
Conclusions Multifactorial interventions including a component to improve medication adherence can lower blood pressure after stroke/TIA. However, it is not possible to say whether or not this is achieved through better medication adherence. Trials are needed of well-characterized interventions to improve medication adherence and clinical outcomes with measurement along the hypothesized causal pathway.
Source: JAHA:Journal of the American Heart Association - August 20, 2013 Category: Cardiology Authors: De Simoni, A., Hardeman, W., Mant, J., Farmer, A. J., Kinmonth, A. L. Tags: Stroke Source Type: research

Leukoaraiosis and Increased Cerebral Susceptibility to Ischemia: Lack of Confounding by Carotid Disease Stroke
Conclusions The association with more severe ischemic events (stroke versus TIA) and infarction on imaging is consistent with leukoaraiosis being a marker of increased cerebral susceptibility to ischemia. In contrast, the presence, severity of, and risk factors for atheromatous disease showed no association with leukoaraiosis, suggesting that these are two unrelated disease processes.
Source: JAHA:Journal of the American Heart Association - August 20, 2013 Category: Cardiology Authors: Schulz, U. G., Gruter, B. E., Briley, D., Rothwell, P. M. Tags: Stroke Source Type: research

Temporal Trends in Patient Characteristics and Treatment With Intravenous Thrombolysis Among Acute Ischemic Stroke Patients at Get With the Guidelines-Stroke Hospitals Original Articles
Conclusions— The frequency of IV tPA use among all AIS patients, regardless of contraindications, nearly doubled from 2003 to 2011. Treatment with tPA has expanded to include more patients with mild deficits, nonwhite race/ethnicity, and oldest old age.
Source: Circulation: Cardiovascular Quality and Outcomes - September 17, 2013 Category: Cardiology Authors: Schwamm, L. H., Ali, S. F., Reeves, M. J., Smith, E. E., Saver, J. L., Messe, S., Bhatt, D. L., Grau-Sepulveda, M. V., Peterson, E. D., Fonarow, G. C. Tags: Acute Cerebral Infarction, Embolic stroke, Thrombolysis Original Articles Source Type: research

Clinical and Magnetic Resonance Imaging Predictors of Very Early Neurological Response to Intravenous Thrombolysis in Patients With Middle Cerebral Artery Occlusion Stroke
Conclusions Lack of VENI provides an early estimate of 3-month outcome and recanalization after IV-tPA. Baseline NIHSS, onset to treatment time, and diffusion weighted imaging—Alberta Stroke Programme Early CT Score could help to predict lack of VENI and, in turn, might help early selection of candidates for complementary reperfusion strategies.
Source: JAHA:Journal of the American Heart Association - December 5, 2013 Category: Cardiology Authors: Apoil, M., Turc, G., Tisserand, M., Calvet, D., Naggara, O., Domigo, V., Baron, J.-C., Oppenheim, C., Touze, E. Tags: Stroke Source Type: research

Vitamin C Intake, Circulating Vitamin C and Risk of Stroke: A Meta-Analysis of Prospective Studies Stroke
Conclusions This meta-analysis suggests significant inverse relationships between dietary vitamin C intake, circulating vitamin C, and risk of stroke.
Source: JAHA:Journal of the American Heart Association - November 27, 2013 Category: Cardiology Authors: Chen, G.-C., Lu, D.-B., Pang, Z., Liu, Q.-F. Tags: Stroke Source Type: research

Clinical Prediction Model Suitable for Assessing Hospital Quality for Patients Undergoing Carotid Endarterectomy Stroke
Conclusions The NCDR CEA score, comprising 7 clinical variables, predicts in-hospital stroke or death after CEA. This model can be used to estimate hospital risk-adjusted outcomes for CEA and to assist with the assessment of hospital quality.
Source: JAHA:Journal of the American Heart Association - June 17, 2014 Category: Cardiology Authors: Wimmer, N. J., Spertus, J. A., Kennedy, K. F., Anderson, H. V., Curtis, J. P., Weintraub, W. S., Singh, M., Rumsfeld, J. S., Masoudi, F. A., Yeh, R. W. Tags: Stroke Source Type: research

Abstract 12: Accuracy and Validation of an Automated Electronic Medical Record Algorithm to Identify Patients with Atrial Fibrillation at Risk for Stroke Session Title: Concurrent I Session B: Oral Abstracts on Stroke Topics
Discussion: Automated methods can be used to identify patients with prevalent AF indicated for anticoagulation, but may suffer from misclassification of up to 12%. Misclassification is minimized by requiring a diagnosis of AF within the prior year and using a CHA2DS2-Vasc based algorithm. Despite differences in accuracy between definitions, system-wide anticoagulation rates assessed using these definitions were similar. The diagnosis codes validated in this study can be applied for internal quality improvement and observational studies, and might be adapted for use in nationwide quality reporting programs.
Source: Circulation: Cardiovascular Quality and Outcomes - June 2, 2014 Category: Cardiology Authors: Navar-Boggan, A. M., Rymer, J., Piccini, J. P., Shatila, W., Ring, L., Stafford, J., Al-Khatib, S. M., Peterson, E. Tags: Session Title: Concurrent I Session B: Oral Abstracts on Stroke Topics Source Type: research

Assessment of the Completeness and Accuracy of Case Ascertainment in the Michigan Stroke Registry Original Articles
Conclusions— Among registry hospitals, these results revealed relatively high levels of completeness and accuracy. Matching registry data to hospital discharge data identified hospitals that changed their case ascertainment method to a case sampling approach. This study illustrates the value of monitoring case ascertainment in stroke registries using external data sources.
Source: Circulation: Cardiovascular Quality and Outcomes - September 16, 2014 Category: Cardiology Authors: Reeves, M. J., Nickles, A. V., Roberts, S., Hurst, R., Lyon-Callo, S. Tags: Health policy and outcome research, Acute Cerebral Infarction, Other Stroke Treatment - Medical Original Articles Source Type: research

Risk Factor Stratification for Intracranial Stenosis in Taiwanese Patients With Cervicocerebral Stenosis Stroke
Conclusions CEIS was associated with higher odds of ischemic stroke compared with isolated ICS and isolated ECS. Smoking and diabetes mellitus, major determinants of CEIS and isolated ICS, should be targeted in therapeutic strategies to reduce the risk of ischemic stroke.
Source: JAHA:Journal of the American Heart Association - December 15, 2015 Category: Cardiology Authors: Sung, Y.-F., Lee, J.-T., Tsai, C.-L., Lin, C.-C., Hsu, Y.-D., Lin, J.-C., Chu, C.-M., Peng, G.-S. Tags: Stroke Source Type: research

Effectiveness of Left Atrial Appendage Exclusion Procedures to Reduce the Risk of Stroke: A Systematic Review of the Evidence Original Articles
Conclusions— There is limited evidence that the Watchman device may be noninferior to long-term OAC in selected patients. Data on effectiveness of LAA exclusion devices is lacking in patients ineligible for long-term OAC. Percutaneous LAA devices are associated with high rates of procedure-related harms. Although surgical LAA exclusion during heart surgery does not seem to add incremental harm, there is insufficient evidence of benefit.
Source: Circulation: Cardiovascular Quality and Outcomes - July 18, 2016 Category: Cardiology Authors: Noelck, N., Papak, J., Freeman, M., Paynter, R., Low, A., Motuapuaka, M., Kondo, K., Kansagara, D. Tags: Atrial Fibrillation, Anticoagulants, Cardiovascular Surgery, Complications, Ischemic Stroke Original Articles Source Type: research

Impact of Insurance Status on Outcomes and Use of Rehabilitation Services in Acute Ischemic Stroke: Findings From Get With The Guidelines-Stroke Health Services and Outcomes Research
The objective was to determine whether patients without insurance or with government‐sponsored insurance had worse quality of care or in‐hospital outcomes in acute ischemic stroke.Methods and ResultsMultivariable logistic regressions with generalized estimating equations stratified by age under or at least 65 years were adjusted for patient demographics and comorbidities, presenting factors, and hospital characteristics to determine differences in in‐hospital mortality and postdischarge destination. We included 589 320 ischemic stroke patients treated at 1604 US hospitals participating in the Get With The Guideline...
Source: JAHA:Journal of the American Heart Association - November 13, 2016 Category: Cardiology Authors: Medford-Davis, L. N., Fonarow, G. C., Bhatt, D. L., Xu, H., Smith, E. E., Suter, R., Peterson, E. D., Xian, Y., Matsouaka, R. A., Schwamm, L. H. Tags: Ischemic Stroke Original Research Source Type: research

Age-Specific Vascular Risk Factor Profiles According to Stroke Subtype Stroke
BackgroundIschemic and hemorrhagic stroke are increasingly recognized as heterogeneous diseases with distinct subtypes and etiologies. Information on variation in distribution of vascular risk factors according to age in stroke subtypes is limited. We investigated the prevalence of vascular risk factors in stroke subtypes in relation to age.Methods and ResultsWe studied a prospective multicenter university hospital–based cohort of 4033 patients. For patients with ischemic stroke caused by large artery atherosclerosis, small vessel disease, or cardioembolism and for patients with spontaneous intracerebral hemorrhage or an...
Source: JAHA:Journal of the American Heart Association - May 8, 2017 Category: Cardiology Authors: Hauer, A. J., Ruigrok, Y. M., Algra, A., van Diȷk, E. J., Koudstaal, P. J., Luiȷckx, G.–J., Nederkoorn, P. J., van Oostenbrugge, R. J., Visser, M. C., Wermer, M. J., Kappelle, L. J., Kliȷn, C. J. M., the Dutch Parelsnoer Instit Tags: Risk Factors, Intracranial Hemorrhage, Ischemic Stroke Original Research Source Type: research

Risk of Ischemic Stroke Associated With Calcium Supplements With or Without Vitamin D: A Nested Case-Control Study Stroke
BackgroundThere is controversy surrounding the risk of ischemic stroke associated with the use of calcium supplements either in monotherapy or in combination with vitamin D.Methods and ResultsA nested case‐control study was performed with patients aged 40 to 89 years old, among whom a total of 2690 patients had a first episode of nonfatal ischemic stroke and for which 19 538 controls were randomly selected from the source population and frequency‐matched with cases for age, sex, and calendar year. Logistic regression provided the odds ratios while adjusting for confounding factors. A sensitivity analysis was performe...
Source: JAHA:Journal of the American Heart Association - May 18, 2017 Category: Cardiology Authors: de Abaȷo, F. J., Rodriguez-Martin, S., Rodriguez-Miguel, A., Gil, M. J. Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke Original Research Source Type: research

Efficacy of a Chronic Care-Based Intervention on Secondary Stroke Prevention Among Vulnerable Stroke Survivors: A Randomized Controlled Trial Original Articles
Conclusions This intervention did not improve SBP control beyond that attained in usual care among vulnerable stroke survivors. A community-centered component could strengthen the intervention impact. Clinical Trial Registration URL: https://clinicaltrials.gov. Unique identifier: NCT00861081.
Source: Circulation: Cardiovascular Quality and Outcomes - January 10, 2018 Category: Cardiology Authors: Cheng, E. M., Cunningham, W. E., Towfighi, A., Sanossian, N., Bryg, R. J., Anderson, T. L., Barry, F., Douglas, S. M., Hudson, L., Ayala-Rivera, M., Guterman, J. J., Gross-Schulman, S., Beanes, S., Jones, A. S., Liu, H., Vickrey, B. G. Tags: Risk Factors, Secondary Prevention, Health Services, Quality and Outcomes, Cerebrovascular Disease/Stroke Original Articles Source Type: research