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Condition: Hole in the Heart

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Total 209 results found since Jan 2013.

The unnatural history of an atrial septal defect: Longitudinal 35 year follow up after surgical closure at young age
Conclusions Very long-term outcome after surgical ASD closure in childhood shows good survival and low morbidity. Early surgical closure prevents pulmonary hypertension and reduces the occurrence of supraventricular arrhythmias. Early postoperative arrhythmias are predictive for the need for pacemaker implantation during early follow-up, but the rate of late pacemaker implantation remains low. Although RVEF was unexpectedly found to be decreased in one-third of patients, the functional status remains excellent.
Source: Heart - August 15, 2013 Category: Cardiology Authors: Cuypers, J. A. A. E., Opic, P., Menting, M. E., Utens, E. M. W. J., Witsenburg, M., Helbing, W. A., van den Bosch, A. E., Ouhlous, M., van Domburg, R. T., Meijboom, F. J., Bogers, A. J. J. C., Roos-Hesselink, J. W. Tags: Congenital Heart Disease, Congenital heart disease, Drugs: cardiovascular system, Echocardiography, Hypertension, Clinical diagnostic tests, Epidemiology Source Type: research

Major adverse cardiovascular events in adult congenital heart disease: a population-based follow-up study from Taiwan
Conclusions: After a median of 11 years of follow-up, the Taiwanese patients with ConHD were at an increased risk of life-long cardiovascular MACE, including heart failure, stroke, acute coronary syndrome, and malignant dysrhythmia. Surgical correction may help to decrease long-term MACE in ConHD patients, especially those with ASD.
Source: BMC Cardiovascular Disorders - March 21, 2014 Category: Cardiology Authors: Yu-Sheng LinPi-Hua LiuLung-Sheng WuYu-Ming ChenChee-Jen ChangPao-Hsien Chu Source Type: research

HeartStitch touts new PFO closure method
Structural heart focused HeartStitch said today its NobleStitch EL device was used to repair 3 patients with patent forman ovale heart defects in Astana, Kazakhstan. A patent foramen ovale is a congenital heart disease in which hole in the heart that normally seals at birth remains open, and can lead to severe migraines, visual auras and stroke, the company said. The procedures were performed by Dr. Michael Mullen and guided by Anthony Nobles at the National Research Cardiac Surgery Center in Astana, according to the company. “We are gratified that our colleagues from abroad have brought this technology to Kazakhstan...
Source: Mass Device - September 11, 2015 Category: Medical Equipment Authors: Fink Densford Tags: Cardiac Implants Cardiovascular HeartStitch Source Type: news

Medtech approvals: FDA releases August 2015 PMAs
The FDA today released its list of the pre-market approvals it granted for medical devices in August 2015: Summary of PMA Originals & Supplements Approved Originals: 2 Supplements: 70 Summary of PMA Originals Under Review Total Under Review: 57 Total Active: 28 Total On Hold: 29 Summary of PMA Supplements Under Review Total Under Review: 569 Total Active: 422 Total On Hold: 147 Summary of All PMA Submissions Originals: 5 Supplements: 90 Summary of PMA Supplement PMA Approval/Denial Decision Times Number of Approvals: 70 Number of Denials: 0 Average Days Fr Receipt to Decision (Total Time): 229.0 FDA Time: 130...
Source: Mass Device - October 23, 2015 Category: Medical Equipment Authors: Brad Perriello Tags: Food & Drug Administration (FDA) Pre-Market Approval (PMA) Regulatory/Compliance Source Type: news

Quantification of Shunt Volume Through Ventricular Septal Defect by Real-Time 3-D Color Doppler Echocardiography: An Study
Quantification of shunt volume is important for ventricular septal defects (VSDs). The aim of the in vitro study described here was to test the feasibility of using real-time 3-D color Doppler echocardiography (RT3-D-CDE) to quantify shunt volume through a modeled VSD. Eight porcine heart phantoms with VSDs ranging in diameter from 3 to 25 mm were studied. Each phantom was passively driven at five different stroke volumes from 30 to 70 mL and two stroke rates, 60 and 120 strokes/min. RT3-D-CDE full volumes were obtained at color Doppler volume rates of 15, 20 and 27 volumes/s.
Source: Ultrasound in Medicine and Biology - February 2, 2016 Category: Radiology Authors: Meihua Zhu, Muhammad Ashraf, Lydia Tam, Cole Streiff, Sumito Kimura, Eriko Shimada, David J. Sahn Tags: Original Contribution Source Type: research

Atrial Septal Defects and Cardioembolic Strokes
Atrial septal defects (ASDs) can be complicated by cardioembolic strokes, but the exact incidence is unknown. Patients with large and small shunts may present with a cardioembolic stroke. Patients with cryptogenic strokes should have cardiac ultrasound to see if an ASD is present. Cardioembolic strokes associated with ASD principally occur with 2 mechanisms. The first is paradoxic embolism involving a venous-based source of thrombus, which may subsequently pass through the ASD by right-to-left shunting, causing a cardioembolic stroke. The second is atrial fibrillation that can complicate the course of patients with ASDs, e...
Source: Cardiology Clinics - March 9, 2016 Category: Cardiology Authors: Michelle Leppert, Sharon N. Poisson, John D. Carroll Source Type: research

MassDevice.com +5 | The top 5 medtech stories for May 26, 2016
Say hello to MassDevice +5, a bite-sized view of the top five medtech stories of the day. This feature of MassDevice.com’s coverage highlights our 5 biggest and most influential stories from the day’s news to make sure you’re up to date on the headlines that continue to shape the medical device industry. Get this in your inbox everyday by subscribing to our newsletters.   5. Ortho Kinematics wins Health Canada nod for VMA system Ortho Kinematics said today it won Health Canada authorization for its Vertebral Motion Analysis spinal imaging system. The VMA system from Austin, Texas-based Ortho Kinema...
Source: Mass Device - May 26, 2016 Category: Medical Equipment Authors: MassDevice Tags: Blog Plus 5 Source Type: news

Device Approved to Prevent Second Strokes in Certain Heart Patients
It's for people who had prior stroke related to a hole in the heart Source: HealthDay Related MedlinePlus Page: Stroke
Source: MedlinePlus Health News - October 28, 2016 Category: Consumer Health News Source Type: news

Cardiac myxoma: clinical characteristics, surgical intervention, intra-operative challenges and outcome.
CONCLUSION: The success rate after surgical removal of cardiac myxoma in this study was substantial and complications were rare. PMID: 28762298 [PubMed - as supplied by publisher]
Source: Perfusion - July 1, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Abu Abeeleh M, Saleh S, Alhaddad E, Alsmady M, Alshehabat M, Bani Ismail Z, Massad I, Bani Hani A, Abu Halaweh S Tags: Perfusion Source Type: research

Serial changes in anatomy and ventricular function on dual-source cardiac computed tomography after the Norwood procedure for hypoplastic left heart syndrome
ConclusionCardiac CT can be used to assess serial changes in anatomy and ventricular function after the Norwood procedure in patients with hypoplastic left heart syndrome.
Source: Pediatric Radiology - September 6, 2017 Category: Radiology Source Type: research

Paradoxical embolism: Myth or reality?
Abstract Paradoxical embolism should be suspected in front of a clinical phenomenon of thromboembolism associated with an anatomical right-to-left shunt. Others potential cardiac sources of thromboembolism must be ruled out. Strokes constitute the most frequent clinical manifestations of paradoxical embolism. Right-to-left left shunts are in connection with intracardiac defects (atrial septal defect and patent foramen ovale) or pulmonary arteriovenous malformations. The probability that a discovered PFO is stroke-related can be evaluated by a score. Therapeutic approaches for secondary prevention of recurrent stro...
Source: Annales de Cardiologie et d'Angeiologie - October 30, 2017 Category: Cardiology Authors: Aubry P, Demian H, Brochet E, Juliard JM Tags: Ann Cardiol Angeiol (Paris) Source Type: research

Evaluation of atrial septal defects with 4D flow MRI —multilevel and inter-reader reproducibility for quantification of shunt severity
ConclusionBlood flow and shunt quantification measured at multiple levels and performed by different readers are reproducible and consistent with 4D flow MRI.
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - August 31, 2018 Category: Materials Science Source Type: research

Evaluation of atrial septal defects with 4D flow MRI-multilevel and inter-reader reproducibility for quantification of shunt severity.
CONCLUSION: Blood flow and shunt quantification measured at multiple levels and performed by different readers are reproducible and consistent with 4D flow MRI. PMID: 30171383 [PubMed - as supplied by publisher]
Source: Magma - August 31, 2018 Category: Radiology Authors: Chelu RG, Horowitz M, Sucha D, Kardys I, Ingremeau D, Vasanawala S, Nieman K, Paul JF, Hsiao A Tags: MAGMA Source Type: research

Human Fetal Hearts with Tetralogy of Fallot have Altered Fluid Dynamics and Forces.
In this study, we performed patient-specific ultrasound-based flow simulations of 3 TOF and 7 normal human fetal hearts. TOF right ventricles (RV) had smaller end-diastolic volumes (EDV) but similar stroke volumes (SV), while TOF left ventricles (LV) had similar EDV but slightly increased SV compared to normal ventricles. Simulation showed that TOF ventricles had elevated systolic intra-ventricular pressure gradient (IVPG), and required additional energy for ejection, but IVPG elevations were considered to be mild relative to arterial pressure. TOF RV and LV had similar pressures due to equalization via ventricular septal ...
Source: American Journal of Physiology. Heart and Circulatory Physiology - September 14, 2018 Category: Physiology Authors: Wiputra H, Chen CK, Talbi E, Lim GL, Soomar SM, Biswas A, Mattar CNZ, Bark D, Leo HL, Yap CH Tags: Am J Physiol Heart Circ Physiol Source Type: research

Evaluation of atrial septal defects with 4D flow MRI —multilevel and inter-reader reproducibility for quantification of shunt severity
ConclusionBlood flow and shunt quantification measured at multiple levels and performed by different readers are reproducible and consistent with 4D flow MRI.
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - August 31, 2018 Category: Materials Science Source Type: research