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Condition: Pneumonia

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Total 1895 results found since Jan 2013.

Ischemic Stroke and Infection: A brief update on mechanisms and potential therapies
Biochem Pharmacol. 2021 Sep 17:114768. doi: 10.1016/j.bcp.2021.114768. Online ahead of print.ABSTRACTIschemic stroke triggers a multifaceted inflammatory response in the brain that contributes to secondary brain injury and infarct expansion. In parallel with brain inflammation, ischemic stroke also leads to post-stroke immunosuppression. Stroke-induced leukopenia then predisposes patients to opportunistic infections potentially leading to pneumonia or unrinary tract infections and a worsened stroke outcome. There is evidence that the hypothalamic-pituitary-adrenal axis plays an important role in the etiology of post-stroke...
Source: Biochemical Pharmacology - September 20, 2021 Category: Drugs & Pharmacology Authors: Drishti P Ghelani Hyun Ah Kim Shenpeng R Zhang Grant R Drummond Christopher G Sobey T Michael De Silva Source Type: research

Medical and neurological complications among stroke patients admitted for inpatient care in addis ababa, ethiopia.
CONCLUSIONS: Complications after stroke are common and are major factors contributing to mortality. Being aware of the types of common complications and associated risk factors helps the clinical team involved in the care of stroke patients to make preparations and plans for the best possible care and to take preventive measures that will save a lot of lives with best possible use of meager resources available such as educating the population to avoid oral feeding for patients with altered mental state and physicians to evaluate gag reflex bedside swallowing test and proper positioning of patients to avoid aspiration pneum...
Source: Ethiopian Medical Journal - November 29, 2015 Category: African Health Tags: Ethiop Med J Source Type: research

Complex interplay of multiple biological systems that contribute to post-stroke infections
Publication date: May 2018Source: Brain, Behavior, and Immunity, Volume 70Author(s): Raymond Shim, Connie H.Y. WongAbstractStroke is a leading contributor of death and disability around the world. Despite its recognised debilitating neurological deficits, a devastating clinical complication of surviving stroke patients that needs more attention is infection. Up to half of the patients develop infections after stroke, and a high proportion of them will die as a direct consequence. Major clinical trials that examined preventive antibiotic therapy in stroke patients have demonstrated this method of prevention is not effective...
Source: Brain, Behavior, and Immunity - July 5, 2018 Category: Neurology Source Type: research

Management Protocols and Encountered Complications among Stroke Patients Admitted to Stroke Unit of Jimma University Medical Center, Southwest Ethiopia: Prospective Observational study
ConclusionBoth neurologic and medical complications were common in majority of stroke patients. But the management protocol for stroke patients was sub-optimal and lagging behind the recommended guidelines due to lack of skilled personnel, appropriate treatment and diagnostic agents. The clinical team involved in the care of stroke patients should make preparations to take preventive measures that will save a lot of lives.
Source: Annals of Medicine and Surgery - November 15, 2019 Category: General Medicine Source Type: research

Medical nutrition therapy of stroke patients with dysphagia – 2021
Orv Hetil. 2021 Oct 3;162(40):1601-1609. doi: 10.1556/650.2021.32204.ABSTRACTÖsszefoglaló. A neurológiai betegek körében a dysphagia előfordulása gyakori, és több oka van. Az utóbbi évek kutatásai a közvetlen neurológiai kórokok (beleértve a gyakori stroke) szerepét is részletesen feltárták. Felismerték az ún. néma aspiráció jelentőségét: ez gyakran áll az (aspirációs) pneumonia hátterében, amely sokszor halálos szövődmény lehet. Az ún. poststroke pneumonia fogalma gyökeresen más értelmezésbe helyezte a stroke-ot követő tüdőgyulladások megítélését, jellegzetessége alapjá...
Source: Orvosi Hetilap - October 3, 2021 Category: General Medicine Authors: Andrea Kov ács P ál Tamás Szabó Csaba Óváry Andrea Moln ár M árta Veresné Bálint Katalin Anna B éres-Molnár Andr ás Folyovich Source Type: research

Research progress in stroke-induced immunodepression syndrome (SIDS) and stroke-associated pneumonia (SAP)
Publication date: Available online 6 January 2018 Source:Neurochemistry International Author(s): Dan-Dan Liu, Shi-Feng Chu, Chen Chen, Peng-Fei Yang, Nai-Hong Chen, Xin He In recent years, stroke-induced immunodepression syndrome (SIDS) and the resulting stroke-associated infection (SAI) have become a focus of current research efforts. Inflammatory reactions after stroke promote tissue healing and eliminate necrotic cells, whereas excessive inflammatory reactions may cause secondary damage. Stroke-induced immunodepression not only reduces inflammatory reactions and protects brain tissues but also weakens the resistance of...
Source: Neurochemistry International - January 7, 2018 Category: Neuroscience Source Type: research

Antibiotic therapy for preventing infections in people with acute stroke.
CONCLUSIONS: Preventive antibiotics had no effect on functional outcome or mortality, but significantly reduced the risk of 'overall' infections. This reduction was driven mainly by prevention of urinary tract infection; no effect for pneumonia was found. PMID: 29355906 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - January 22, 2018 Category: General Medicine Authors: Vermeij JD, Westendorp WF, Dippel DW, van de Beek D, Nederkoorn PJ Tags: Cochrane Database Syst Rev Source Type: research

Impact of Dysphagia Assessment and Management on Risk of Stroke-Associated Pneumonia: A Systematic Review
Background: Patients with dysphagia are at an increased risk of stroke-associated pneumonia. There is wide variation in the way patients are screened and assessed during the acute phase. The aim of this review was to identify the methods of assessment and management in acute stroke that influence the risk of stroke-associated pneumonia. Studies of stroke patients that reported dysphagia screening, assessment or management and occurrence of pneumonia during acute phase stroke were screened for inclusion after electronic searches of multiple databases from inception to November 2016. The primary outcome was association with ...
Source: Cerebrovascular Diseases - September 10, 2018 Category: Neurology Source Type: research