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Specialty: Neuroscience
Condition: Pain

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Total 180 results found since Jan 2013.

Comparison of the effectiveness of pulsed radiofrequency of the suprascapular nerve and intra-articular corticosteroid injection for hemiplegic shoulder pain management
J Integr Neurosci. 2021 Sep 30;20(3):687-693. doi: 10.31083/j.jin2003073.ABSTRACTMany patients complain of hemiplegic shoulder pain following stroke. Here, the effectiveness of pulsed radiofrequency stimulation of the suprascapular nerve is compared with intra-articular corticosteroid injection for chronic hemiplegic shoulder pain following stroke. This single-center, prospective, randomized controlled study included 20 patients with hemiplegic shoulder pain after stroke, randomly assigned to the pulsed radiofrequency and intra-articular corticosteroid injection treatment groups (n = 10 in each). Hemiplegic shoulder pain s...
Source: Journal of Integrative Neuroscience - October 14, 2021 Category: Neuroscience Authors: Tae Hoon Kim Min Cheol Chang Source Type: research

Developments in Varicella Zoster Virus Vasculopathy
Abstract Varicella zoster virus (VZV) is a highly neurotropic human herpesvirus. Primary infection usually causes varicella (chicken pox), after which virus becomes latent in ganglionic neurons along the entire neuraxis. VZV reactivation results in zoster (shingles) which is frequently complicated by chronic pain (postherpetic neuralgia). VZV reactivation also causes meningoencephalitis, myelitis, ocular disorders, and vasculopathy, all of which can occur in the absence of rash. This review focuses on the association of VZV and stroke, and on the widening spectrum of disorders produced by VZV vasculopathy in immu...
Source: Current Neurology and Neuroscience Reports - January 11, 2016 Category: Neuroscience Source Type: research

The pathophysiological role of astrocytic endothelin-1
Publication date: Available online 28 April 2016 Source:Progress in Neurobiology Author(s): Stéphanie Hostenbach, Miguel D’haeseleer, Ron Kooijman, Jacques De Keyser In the normal central nervous system, endothelin-1 (ET-1) is found in some types of neurons, epithelial cells of the choroid plexus, and endothelial cells of microvessels, but it is usually not detectable in glial cells. However, in different pathological conditions, astrocytes adapting a reactive phenotype express high levels of ET-1 and its receptors, mainly the ETB receptor. ET-1 released by reactive astrocytes appears mainly to have neurodeleterio...
Source: Progress in Neurobiology - April 28, 2016 Category: Neuroscience Source Type: research

B-11. Application of EEG-based brain computer interface to movement and sensory disorders
To examine the effect of the EEG-based brain computer interface (BCI) training for patients with stroke, writer ’s cramp and neuropathic pain. Method: Using the EEG recorded with Ag/AgCl electrodes placed at C3 and C4, as designated according to the International 10/20 system, we gave real time visual feedback to the patients with PC monitor which is placed in front of them. Participants were required to im agine the affected wrist extending in stroke and neuropathic pain patients. Patients with writer’s cramp were requested to relax their wrist flexor while extending their wrist.
Source: Clinical Neurophysiology - March 30, 2018 Category: Neuroscience Authors: Tetsuo Ota Source Type: research

Interaction of the Left –Right Somatosensory Pathways in Patients With Thalamic Hemorrhage: A Case Report
Neural plasticity compensates for the loss of motor function after stroke. However, whether neural plasticity occurs in the somatosensory pathways after stroke is unknown. We investigated the left–right somatosensory interaction in two hemorrhagic patients using a paired somatosensory evoked potentials (p-SEPs) recorded at CP3 and CP4, which was defined as an amplitude difference between the SEPs of paired median nerve stimulations to both sides and that of single stimulation to the affected side. Patient 1 (61-year-old, left thalamic hemorrhage) has a moderate motor impairment, severe sensory deficit, and complained of ...
Source: Frontiers in Human Neuroscience - November 1, 2021 Category: Neuroscience Source Type: research

Human in silico trials for parametric computational fluid dynamics investigation of cerebrospinal fluid drug delivery: impact of injection location, injection protocol, and physiology
ConclusionThe computational modeling approach provides ability to conduct in silico trials representative of CSF injection protocols. Taken together, the findings indicate a strong potential for delivery protocols to be optimized to reach a target region(s) of the spine and/or brain with a needed therapeutic dose. Parametric modification of bolus rate/volume and flush volume was found to have impact on tracer distribution; albeit to a smaller degree than injection location, with CM and ICV injections resulting in greater therapeutic dose to brain regions compared to LP. CSF stroke volume and frequency both played an import...
Source: Fluids and Barriers of the CNS - January 28, 2022 Category: Neuroscience Source Type: research

The three dimensional assessment of peripheral nerve injury: An integrated clinical, neurophysiologic and sonographic approach
“Time is brain,” a phrase common to neurologists, emphasizes the importance of immediate evaluation for acute stroke (). In the realm of peripheral nerve injury (PNI), the opportunity for acute diagnosis is often dictated by the temporal evolution of neurophysiologic findings, limiting the value of acute assessment. The findings of Padua et al. in this issue of Clinical Neurophysiology may increase the urgency to assess PNI (). PNI owing to traumatic and iatrogenic injury is quite common, with an incidence as high as 34% in traumatic brain injury patients () and is found in up to 5% of all patients admitted to trauma c...
Source: Clinical Neurophysiology - February 4, 2013 Category: Neuroscience Authors: Lisa D. Hobson-Webb, Vern C. Juel Tags: Editorials Source Type: research

P 174. Effects of paired associative stimulation on developmental motor plasticity in children
Introduction: Transcranial magnetic stimulation (TMS) offers increasingly sophisticated means of assessing neurophysiology and neuroplasticity mechanisms but applications in children have been limited. Paired associative stimulation (PAS) is an advanced TMS method that pairs peripheral sensory stimulation with TMS primary motor cortex (M1) stimulation. PAS induces rapid, reversible and topographically specific increases in adult motor cortex excitability consistent with NMDAR-dependent long-term potentiation. PAS has not been studied in the more plastic brains of children.Objectives: Our aim wasto define the developmental ...
Source: Clinical Neurophysiology - September 1, 2013 Category: Neuroscience Authors: O. Damji, J. Roe, S. Shinde, O. Kotsovsky, A. Kirton Tags: Society Proceedings Source Type: research