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Risk of Carotid Stroke after Chiropractic Care: A Population-Based Case-Crossover Study
Chiropractic manipulation is a popular treatment for neck pain and headache, but may increase the risk of cervical artery dissection and stroke. Patients with carotid artery dissection can present with neck pain and/or headache before experiencing a stroke. These are common symptoms seen by both chiropractors and primary care physicians (PCPs). We aimed to assess the risk of carotid artery stroke after chiropractic care by comparing association between chiropractic and PCP visits and subsequent stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - November 20, 2016 Category: Neurology Authors: J. David Cassidy, Eleanor Boyle, Pierre C ôté, Sheilah Hogg-Johnson, Susan J. Bondy, Scott Haldeman Source Type: research

Post-IV thrombolytic headache and hemorrhagic transformation risk in acute ischemic stroke
Conclusion: tPA-associated headache does not predict increased risk of HT and has no other prognostic importance in patients with AIS. Prospective studies with a larger cohort may be needed to further explore this relationship.
Source: Neurology Clinical Practice - February 15, 2016 Category: Neurology Authors: Chaudhry, S. A., Kwon, S. Y., Kneale, H., Al Jajeh, A., Hussain, S., Razak, A. Tags: All Cerebrovascular disease/Stroke, Embolism, Intracerebral hemorrhage Research Source Type: research

Differential Risk Factors and Outcomes of Ischemic Stroke due to Cervical Artery Dissection in Young Adults
Conclusions: While history of migraine and neck manipulation are significantly associated with CeAD, most of the traditional vascular risk factors for stroke are less prevalent in this group when compared to strokes due to other etiologies. For CeAD-related strokes, higher initial stroke severity and history of tobacco use may be associated with higher stroke-related disability, but overall, patients with CeAD have similar outcomes as compared to strokes due to other etiologies.Cerebrovasc Dis
Source: Cerebrovascular Diseases - September 25, 2020 Category: Neurology Source Type: research

Cervical Artery Dissection in Young Adults in the Stroke in Young Fabry Patients (sifap1) Study
Background: Patients with carotid artery dissection (CAD) have been reported to have different vascular risk factor profiles and clinical outcomes to those with vertebral artery dissection (VAD). However, there are limited data from recent, large international studies comparing risk factors and clinical features in patients with cervical artery dissection (CeAD) with other TIA or ischemic stroke (IS) patients of similar age and sex. Methods: We analysed demographic, clinical and risk factor profiles in TIA and IS patients ≤55 years of age with and without CeAD in the large European, multi-centre, Stroke In young FAbry Pa...
Source: Cerebrovascular Diseases - January 23, 2015 Category: Neurology Source Type: research

Sensitivity to acute cerebral ischemic injury in migraineurs: A retrospective case-control study
Conclusions: This case-control study supports the hypothesis that a history of migraine, particularly with aura, is associated with a no-mismatch pattern during acute ischemic stroke, consistent with data obtained in migraine mutant mice.
Source: Neurology - November 30, 2015 Category: Neurology Authors: Mawet, J., Eikermann-Haerter, K., Park, K.-Y., Helenius, J., Daneshmand, A., Pearlman, L., Avery, R., Negro, A., Velioglu, M., Arsava, E. M., Ay, H., Ayata, C. Tags: Migraine, All Cerebrovascular disease/Stroke ARTICLE Source Type: research

Spontaneous cervical internal carotid artery vasospasm: Case report and literature review
We report a case of recurrent TIA caused by alternating cervical ICA spasms. We also performed a MEDLINE search of previous publications in English from 1950 to August 2013. The search was performed with both text word searching and the appropriate MeSH headings of "carotid vasospasm" and "stroke," "cerebrovascular accident," "TIA," or "brain attack." The bibliographies of each of the retrieved articles with similar cases were all reviewed and relevant citations in these listings were evaluated for inclusion in the review.
Source: Nature Clinical Practice - October 13, 2014 Category: Neurology Authors: Huisa, B. N., Roy, G. Tags: Magnetic Source Imaging (MSI), Other cerebrovascular disease/ Stroke, Carotid artery dissection Cases Source Type: research

The migraine-stroke connection: A genetic perspective
Conclusion A wealth of data supports a genetic link between migraine and vascular disease. Based on growing high-throughput data-sets, new genotyping techniques and in-depth phenotyping, further insights are expected for the future.
Source: Cephalalgia - June 1, 2016 Category: Neurology Authors: Malik, R., Winsvold, B., Auffenberg, E., Dichgans, M., Freilinger, T. Tags: Review Articles Source Type: research

Cervical artery dissection in patients >=60 years: Often painless, few mechanical triggers
Conclusion: In our study population of patients diagnosed with CeAD, 1 in 14 was aged ≥60 years. In these patients, pain and mechanical triggers might be missing, rendering the diagnosis more challenging and increasing the risk of missed CeAD diagnosis in older patients.
Source: Neurology - April 3, 2017 Category: Neurology Authors: Traenka, C., Dougoud, D., Simonetti, B. G., Metso, T. M., Debette, S., Pezzini, A., Kloss, M., Grond-Ginsbach, C., Majersik, J. J., Worrall, B. B., Leys, D., Baumgartner, R., Caso, V., Bejot, Y., Compter, A., Reiner, P., Thijs, V., Southerland, A. M., Ber Tags: Stroke in young adults, All Cerebrovascular disease/Stroke, Carotid artery dissection ARTICLE Source Type: research

Craniovertebral Junction Anomalies: An Overlooked Cause of & #39;Posterior Circulation Stroke & #39;
Conclusions: CVJ anomalies can present as posterior circulation infarct. One must evaluate all patients with posterior circulation stroke, especially young patients, for possible CVJ anomalies. Dynamic lateral cervical spine X-ray is an important tool to diagnose AAD. CVJ anomalies represent a treatable cause of VAD.
Source: Neurology India - November 11, 2022 Category: Neurology Authors: Kanwaljeet Garg Vivek Tandon Rajinder Kumar P Sarat Chandra Shashank S Kale Bhawani Shankar Sharma Ashok K Mahapatra Source Type: research

Spontaneous Bilateral Cervical Internal Carotid and Vertebral Artery Dissection in a Japanese Patient without Collagen Vascular Disease with Special Reference to Single-Nucleotide Polymorphisms
Spontaneous cervical artery dissection (sCAD) is a major cause of ischemic stroke in young adults. Frequently, sCAD involves multiple neck arteries, accounting for 13%-28% of the total sCAD cases. However, little is known about factors related to multiple sCAD. In this case, a 52-year-old man was admitted due to headache without aura. There was a personal history of migraine with aura and a family history of similar symptoms. The patient's younger brother had a left vertebral artery (VA) dissecting aneurysm and underwent endovascular occlusion of his parent artery at the age of 48.
Source: Journal of Stroke and Cerebrovascular Diseases - May 19, 2016 Category: Neurology Authors: Arata Abe, Chikako Nito, Yuki Sakamoto, Akane Nogami, Hiroyuki Hokama, Shiro Takahashi, Kumiko Kirita, Masayuki Ueda, Yoshiro Ishimaru, Kazumi Kimura Tags: Case Studies Source Type: research

Antiplatelet treatment compared with anticoagulation treatment for cervical artery dissection (CADISS): a randomised trial
Publication date: Available online 12 February 2015 Source:The Lancet Neurology Background Extracranial carotid and vertebral artery dissection is an important cause of stroke, especially in young people. In some observational studies it has been associated with a high risk of recurrent stroke. Both antiplatelet drugs and anticoagulant drugs are used to reduce risk of stroke but whether one treatment strategy is more effective than the other is unknown. We compared their efficacy in the Cervical Artery Dissection in Stroke Study (CADISS), with the additional aim of establishing the true risk of recurrent stroke. Methods W...
Source: The Lancet Neurology - February 13, 2015 Category: Neurology Source Type: research

Migraine and cerebrovascular diseases: Epidemiology, pathophysiological, and clinical considerations.
In conclusion, migraine is a potential risk factor for cerebrovascular diseases. Migraineurs should be carefully evaluated considering their vascular risk assessment based on current evidence, so that healthcare professionals can provide appropriate and individualized management of other cardiovascular risk factors, notably quitting smoking and restricting use of oral contraceptives. PMID: 30117565 [PubMed - as supplied by publisher]
Source: Headache - August 17, 2018 Category: Neurology Authors: Magalhães JE, Sampaio Rocha-Filho PA Tags: Headache Source Type: research

Migraine and the Risk of Carotid Artery Dissection
Stroke incidence is increasing among patients aged 40 to 60 years —faster than in older age cohorts. Preliminary evidence suggests that ischemic stroke—not hemorrhage or subarachnoid hemorrhage—accounts for the increase. Many speculate that increasing incidences of classic vascular risk factors among young patients contribute to the increased incidence of st roke. Certainly, we are all aware of the obesity epidemic and continued prevalence of smoking, leading to premature atherosclerosis. Furthermore, equally relevant causes of stroke in the young include migraine, drug abuse, cervical arterial dissections, patent fo...
Source: JAMA Neurology - March 6, 2017 Category: Neurology Source Type: research

Review Epidemiology, pathophysiology, diagnosis, and management of intracranial artery dissection
Spontaneous intracranial artery dissection is an uncommon and probably underdiagnosed cause of stroke that is defined by the occurrence of a haematoma in the wall of an intracranial artery. Patients can present with headache, ischaemic stroke, subarachnoid haemorrhage, or symptoms associated with mass effect, mostly on the brainstem. Although intracranial artery dissection is less common than cervical artery dissection in adults of European ethnic origin, intracranial artery dissection is reportedly more common in children and in Asian populations.
Source: Lancet Neurology - May 11, 2015 Category: Neurology Authors: Stéphanie Debette, Annette Compter, Marc-Antoine Labeyrie, Maarten Uyttenboogaart, Tina M Metso, Jennifer J Majersik, Barbara Goeggel-Simonetti, Stefan T Engelter, Alessandro Pezzini, Philippe Bijlenga, Andrew M Southerland, Olivier Naggara, Yannick Béj Tags: Review Source Type: research

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