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Specialty: Respiratory Medicine
Condition: Hypertension

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Total 342 results found since Jan 2013.

Towards the implementation of optimal cardiac magnetic resonance risk stratification in PAH
Chest. 2023 Jul 30:S0012-3692(23)01066-8. doi: 10.1016/j.chest.2023.07.028. Online ahead of print.ABSTRACTBACKGROUND: The 2022 European pulmonary hypertension (PH) guidelines incorporate cardiac magnetic resonance (CMR) imaging metrics in the risk stratification of pulmonary arterial hypertension (PAH) patients. Thresholds to identify patients at estimated 1-year mortality risks of <5%, 5-20% and >20% are introduced. However, these cut-off values are mostly single center based and require external validation.RESEARCH QUESTIONS: What are the discriminative prognostic properties of the current cardiac magnetic resonanc...
Source: Chest - August 1, 2023 Category: Respiratory Medicine Authors: L R Celant J N Wessels J T Marcus L J Meijboom H J Bogaard F S de Man A Vonk Noordegraaf Source Type: research

The Right Ventricle in Pulmonary Hypertension
Semin Respir Crit Care Med. 2023 Jul 24. doi: 10.1055/s-0043-1770117. Online ahead of print.ABSTRACTThe right ventricle plays a pivotal role in patients with pulmonary hypertension (PH). Its adaptation to pressure overload determines a patient's functional status as well as survival. In a healthy situation, the right ventricle is part of a low pressure, high compliance system. It is built to accommodate changes in preload, but not very well suited for dealing with pressure overload. In PH, right ventricular (RV) contractility must increase to maintain cardiac output. In other words, the balance between the degree of RV con...
Source: Respiratory Care - July 24, 2023 Category: Respiratory Medicine Authors: Jeroen N Wessels Lucas R Celant Frances S de Man Anton Vonk Noordegraaf Source Type: research

Establishing minimally important differences for cardiac MRI endpoints in pulmonary arterial hypertension
CONCLUSION: This study establishes clinically relevant CMR MIDs for how a patient feels, functions or survives in response to PAH treatment. These findings provide further support for the use of CMR as a clinically relevant clinical outcome measure and will aid trial-size calculations for studies using CMR.PMID:37414419 | DOI:10.1183/13993003.02225-2022
Source: Respiratory Care - July 6, 2023 Category: Respiratory Medicine Authors: Samer Alabed Pankaj Garg Faisal Alandejani Krit Dwivedi Ahmed Maiter Kavita Karunasaagarar Smitha Rajaram Catherine Hill Steven Thomas Rebecca Gossling Michael Sharkey Mahan Salehi Jim M Wild Lisa Watson Abdul Hameed Athanasios Charalampopoulos Haiping Lu Source Type: research

Association between REM-related mild obstructive sleep apnea and common cardiometabolic diseases
ConclusionCommon CMDs, particularly HT, tend to show an association with REM-OSA in patients with  mild OSA, but this association did not reach statistically significant levels.
Source: Sleep and Breathing - April 28, 2023 Category: Respiratory Medicine Source Type: research

Frequency of delirium and its associated factors among COVID ‐19 inpatients in Iran
ConclusionIn view of the high frequency of delirium among COVID-19 inpatients, their screening for this important mental state should be a priority in clinical settings.
Source: The Clinical Respiratory Journal - April 13, 2023 Category: Respiratory Medicine Authors: Fatemeh Alizadeh Arimi, Mehran Zarghami, Mahmood Moosazadeh, Hossein Mehravaran, Faranak Sedighi, Roya Ghasemian, Forouzan Elyasi Tags: ORIGINAL ARTICLE Source Type: research

Frequency of delirium and its associated factors among COVID-19 inpatients in Iran
CONCLUSION: In view of the high frequency of delirium among COVID-19 inpatients, their screening for this important mental state should be a priority in clinical settings.PMID:37054699 | DOI:10.1111/crj.13609
Source: Respiratory Care - April 13, 2023 Category: Respiratory Medicine Authors: Fatemeh Alizadeh Arimi Mehran Zarghami Mahmood Moosazadeh Hossein Mehravaran Faranak Sedighi Roya Ghasemian Forouzan Elyasi Source Type: research

COPD and COVID-19: a dangerous association?
Conclusion: COPDs patients are mostly ederly men with comorbidities. The most effective treatment for them was stabilization of comorbidities and conventional oxygen and for the most severe Helmet-CPAP and NIV. In addition, COPD patients had no higher risk of mortality from COVID-19 than individuals without a pre-existing diagnosis of COPD.
Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Mendez Gonzalez, L., Ferreira, J., Caneiras, C. Tags: 05.02 - Monitoring airway disease Source Type: research

Comorbidities in patients with Obstructive Sleep Apnea syndrome (OSAS) in Reunion Island.
Conclusion: Morbid obesity, hypertension, diabetes, heart disease and respiratory illness are a predictor of severe OSAS in our patients especially snorers.
Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Omarjee, B., Budhan, S., Kichenin, C., Omarjee, A., Vellin, J. F. Tags: 01.01 - Clinical problems - no related to asthma or COPD Source Type: research

Acute beat blockade improves right ventricular diastolic filling in pulmonary arterial hypertension: a rodent CMR and clinical human pressure-volume study
Conclusions: Esmolol improves RV diastolic filling in PAH at rest and during low-grade exercise, preserving SV and CO, with energetically favourable effects on contractile efficiency.
Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Samaranayake, C., Niglas, M., Kempny, A., Baxan, N., Ashek, A., Pinguel, J., Dimopoulos, K., Price, L. C., Wort, S. J., Zhao, L., Mccabe, C. Tags: 13.01 - Pulmonary hypertension Source Type: research

Impact of cardiovascular disease on in-hospital mortality in patients with COVID-19
Conclusion: COVID-19 patients with CVD comorbidites have a higher risk of in-hospital death. Optimal care and good control of CVD are essential in this patient group.
Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Pencheva Genova, V., Pancheva, R., Stoimenov, B., Manov, E., Kolev, V., Tsrancheva, R., Koshtikova, K., Stoianov, D., Donev, S. Tags: 01.01 - Clinical problems - no related to asthma or COPD Source Type: research

Prevalence of cardiovascular disease in alpha-1 antrypsin deficiency
We present prevalence of CVD from 1158 patients with AATD who are prospectively followed up as part of the Birmingham AATD registry in the UK. All diagnoses come from either central NHS records or patient reports.The prevalence of CVD was as follows: ischaemic heart disease, 5.2%; heart failure, 0.7%, myocardial infarction, 0.9%; stroke, 1.9%; atrial fibrillation 2.4%. Hypertension and hyperlipidaemia were present in 22% and 10.7% of patients respectively. Factors associated with a higher prevalence of CVD include being male (p <0.001), older age (p <0.001), lower KCO (p = 0.008) and presence of hyperlipidaemia ...
Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Bailey, E., Ellis, P., Turner, A., Ellis, P. Tags: 05.02 - Monitoring airway disease Source Type: research