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Want to Live Longer? Science Says to Do These 5 Things
When it comes to staying healthy, most people have the same motivation: living as long and fulfilling a life as possible. And while science has yet to find a true fountain of youth, researchers have identified certain behaviors that can increase longevity. One study, published in the journal Circulation last year, even argued that adhering to just five healthy habits could extend your lifespan by roughly a decade. Here’s what they are, and what research to date says about living your longest life. Eating a healthy diet Diet is strongly linked to longevity. Research has long suggested that following a Mediterranean di...
Source: TIME: Health - April 19, 2019 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized Longevity Source Type: news

NAMPT as a Dedifferentiation-Inducer Gene: NAD+ as Core Axis for Glioma Cancer Stem-Like Cells Maintenance
Conclusion and Perspectives Gliomas are the most prevalent primary brain cancer in adults and include a broad category of tumors including astrocytoma, oligodendroglioma, and GBM. Regardless of tumor aggressiveness, malignancy, and infiltration, these glia-derived tumors rarely exceed a median survival time of 12–14 months. Driven by the infiltrative nature of these tumors, the clinical approach is difficult and relapses often occur with fatal consequences. These unsuccessful attempts to control glioma's fate have fostered research looking for more effective therapies. (GSCs) are a small subset of CD133&#...
Source: Frontiers in Oncology - May 2, 2019 Category: Cancer & Oncology Source Type: research

Correlates of HIV RNA concentrations in cerebrospinal fluid during antiretroviral therapy: a longitudinal cohort study
Publication date: Available online 14 June 2019Source: The Lancet HIVAuthor(s): Alessandro Livelli, Florin Vaida, Ronald J Ellis, Qing Ma, Micol Ferrara, David B Clifford, Ann C Collier, Benjamin B Gelman, Christina M Marra, Justin C McArthur, J Allen McCutchan, Susan Morgello, Ned Sacktor, David M Simpson, Igor Grant, Scott L Letendre, Ian Abramson, Muhammad T. Al-Lozi, Sarah L. Archibald, J. Hampton AtkinsonSummaryBackgroundFew large projects have evaluated the factors that influence the HIV RNA concentrations (viral load) in cerebrospinal fluid (CSF) during antiretroviral therapy (ART) over time. We aimed to determine t...
Source: The Lancet HIV - June 16, 2019 Category: Infectious Diseases Source Type: research

Highlighting the role of cognitive and brain reserve in the substance use disorder field.
CONCLUSION: CR and BR are variables not taken yet into account in drug addiction. However, they could give us a valuable information about people at risk, as well as patient's prognosis. PMID: 31204624 [PubMed - as supplied by publisher]
Source: Current Neuropharmacology - June 15, 2019 Category: Drugs & Pharmacology Authors: Cutuli D, de Guevara-Miranda DL, Castilla-Ortega E, Santín LJ, Sampedro-Piquero P Tags: Curr Neuropharmacol Source Type: research

Growth at four health care sites grows access in Niagara Falls
In the past month alone, three organizations completed or announced projects that provide more services related to addictions and mental health, neurosurgical and stroke care as well as orthopedics.
Source: bizjournals.com Health Care:Pharmaceuticals headlines - August 8, 2019 Category: Pharmaceuticals Authors: Tracey Drury Source Type: news

Efficacy of smoking cessation with varenicline plus counselling for e-cigarettes users (VAREVAPE): A protocol for a randomized controlled trial.
Abstract Tobacco smoking is a global pandemic that poses substantial health burdens and costs. With nearly six million deaths annually, smoking is the single most important cause of avoidable premature mortality in the world, mainly from lung cancer, coronary heart disease, chronic obstructive pulmonary disease and stroke. Smoking is a very difficult addiction to break, even for those with a strong desire to quit. Electronic cigarettes are an attractive long-term alternative source of nicotine to conventional cigarettes because of their many similarities with smoking. Electronic cigarette users report buying them ...
Source: Clinical Lung Cancer - August 8, 2019 Category: Cancer & Oncology Authors: Caponnetto P, Maglia M, Polosa R Tags: Contemp Clin Trials Commun Source Type: research

Cameroon: 'If the Brain Doesn't Work, the Rest Doesn't Matter'
[Cameroon Tribune] Our brains are currently at serious risk because of diseases such as epilepsy, stroke, AIDS, dementia and so on. There is also danger from drug abuse and addictions, especially amongst youths, resulting in behavioural disorders which contribute to some of the major crises the nation is facing. Therefore, brain or mental health problems stand among the most common and severe in Cameroon. In the following interview, Prof. Alfred Kongnyu Njamnshi, lecturer, Faculty of Medicine and Biomedical Sciences, Univers
Source: AllAfrica News: Health and Medicine - September 12, 2019 Category: African Health Source Type: news

How the Vaping Industry Is Using a Defensive Tactic Pioneered Decades Ago by Big Tobacco
Each week brings a new story of some calamity brought by vaping. In late July, a Connecticut man filed suit against e-cigarette giant Juul Labs after suffering a massive stroke. The suit alleges that he became addicted while he was still a high schooler, even though the company says it is specifically taking action to prevent young people from trying the product. In August, an Illinois patient died after vaping, succumbing to a mysterious respiratory illness; news broke teens in the Midwest hospitalized with severe and unexplained respiratory symptoms; and the FDA announced that that it was investigating the relationship b...
Source: TIME: Health - October 2, 2019 Category: Consumer Health News Authors: Sarah Milov Tags: Uncategorized health Opinion politics Source Type: news

Nicotinamide phosphoribosyltransferase contributes to cocaine addiction through sirtuin 1.
Authors: Singh S, William M, Chu XP Abstract Drug addiction is a persistent mental illness and there is no effective treatment. The precise mechanisms underlying addictive responses have not been completely understood, although ion channels, neurotransmitters as well as their receptors, and intracellular endogenous molecules in the brain have been shown to play important roles in cocaine addiction. Nicotinamide phosphoribosyltransferase (NAMPT) is an important rate-limiting enzyme found throughout the body that converts the intracellular pool of nicotinamide adenine dinucleotide (NAD) into nicotinamide mononucleoti...
Source: International Journal of Physiology, Pathophysiology and Pharmacology - January 31, 2020 Category: Physiology Tags: Int J Physiol Pathophysiol Pharmacol Source Type: research

Sleep disorders and disrupted sleep in addiction, withdrawal and abstinence with focus on alcohol and opioids
Sleep is very important for our physical and mental health. Sleep disturbances increase risk of substance use disorders as well as risk of onset and worsening of medical and other primary psychiatric problems like diabetes, kidney disease, high blood pressure, heart disease, stroke, and depression [1,2]. Substance use disorders, particularly alcohol and opioids can cause or exacerbate sleep disturbances [3,4] leading to even greater problems with our health in addition to the consequences of substance use [1,2].
Source: Journal of the Neurological Sciences - January 29, 2020 Category: Neurology Authors: William-Bernard Reid-Varley, Caridad Ponce-Martinez, Khurshid A. Khurshid Tags: Review Article Source Type: research

NIH Slated for 7 percent Budget Cut
The President has proposed a $38.7 billion budget for the National Institutes of Health in fiscal year (FY) 2021. This translates to a $3 billion or 7 percent cut in the agency’s funding compared to FY 2020. The NIH budget request includes a $50 million initiative to use artificial intelligence (AI) to develop a better understanding of the causes of chronic diseases and to identify early treatments. This plan is in line with the Administration’s “Industries of the Future” effort, which supports using and developing AI across sectors. The budget would provide $50 million for the Childhood Cancer ...
Source: Public Policy Reports - February 18, 2020 Category: Biology Authors: AIBS Source Type: news

More employers opening door to acupuncture as demand for drug-free care grows
As the opioid crisis continues across America, employers are searching for ways to help employees battle their ailments with therapies that have the dual benefit of being non-addictive and cost effective. To do that, many are removing access barriers to drug-free care like acupuncture that can help with a variety of conditions including back pain, carpal tunnel, hypertension, migraine and stroke recovery. Deb Zurcher, a doctor of chiropractic, licensed acupuncturist and a clinical executive with…
Source: bizjournals.com Health Care:Biotechnology headlines - March 13, 2020 Category: Biotechnology Authors: Laura Newpoff Source Type: news

Marketing Messages in Continuing Medical Education (CME) Modules on Binge-Eating Disorder (BED)
Conclusions: It seems that CME is being used to promote lisdexamfetamine for weight loss (a contraindicated use) and to highlight benefits of lisdexamfetamine while underplaying the risks.
Source: Journal of the American Board of Family Medicine - March 15, 2020 Category: Primary Care Authors: Jung, J., Fugh-Berman, A. Tags: Original Research Source Type: research

WHRY funds studies on stroke, endometrial cancer, and addiction to opioids
Women ’s Health Research at Yale is expanding its work to “address the enduring and pressing medical conditions that continue to affect women’s lives.”
Source: Yale Science and Health News - May 21, 2020 Category: Universities & Medical Training Source Type: news