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Managing uncertainty: Physicians' decision-making for stroke prevention for patients with atrial fibrillation and intracerebral haemorrhage
Conclusion Physicians described the process of deciding on stroke prevention in patients with AF post-ICH as 'challenging' due to considerable 'clinical equipoise'. Key factors that affected decision-making was patient comorbidities, functional status, and patient willingness to engage with oral anticoagulation therapy. Shared decision-making was believed to be beneficial, but physicians believed that the ultimate responsibility to decide on stroke prevention lay with the clinician.PMID:35253141 | DOI:10.1055/a-1789-4824
Source: Thrombosis and Haemostasis - March 7, 2022 Category: Hematology Authors: Elena Ivany Robyn Lotto Gregory Yh Lip Deirdre Lane Source Type: research

Ocular and systemic determinants of perifoveal and macular vessel parameters in healthy African Americans
CONCLUSIONS: When interpreting OCTA images in a clinical setting, it is important to consider the effects ocular and systemic characteristics may have on the macular microcirculation.PMID:34740885 | DOI:10.1136/bjophthalmol-2021-319675
Source: The British Journal of Ophthalmology - November 6, 2021 Category: Opthalmology Authors: Grace M Richter Jae Chang Lee Nasir Khan Alexander Vorperian Brennan Hand Bruce Burkemper Xiao Zhou Zhongdi Chu Ruikang Wang Rohit Varma Amir H Kashani Source Type: research

Drug overdose and the risk of cardiovascular diseases: a nested case –control study
ConclusionsDrug overdose appears to be associated with increased risk of cardiovascular diseases.Graphic abstract
Source: Clinical Research in Cardiology - October 15, 2021 Category: Cardiology Source Type: research

A Prospective Epidemiological Analysis of Controlling Nutritional Status Score with the Poor Functional Outcomes in Chinese Patients with Hemorrhagic Stroke
Br J Nutr. 2021 Aug 19:1-18. doi: 10.1017/S0007114521003184. Online ahead of print.ABSTRACTNutritional Risk Screening index is a standard tool to assess nutritional risk, but epidemiological data are scarce on Controlling Nutritional Status (CONUT) as a prognostic marker in acute hemorrhagic stroke (AHS). We aimed to explore whether the CONUT may predict a 3-month functional outcome in AHS. In total, 349 Chinese patients with incident AHS were consecutively recruited, and their malnutrition risks were determined using a high CONUT score of ≥ 2. The cohort patients were divided into high-CONUT (≥ 2) and low-CONUT (< ...
Source: The British Journal of Nutrition - August 19, 2021 Category: Nutrition Authors: Bei-Lei Zhu Yan-Zhi Wu Zhong-Ming Cai Cheng-Wei Liao Le-Qiu Sun Zhi-Peng Liu Hao-Man Chen Xue-Rong Huang Qun-Li Lin Xu-Dong Zhou Liang Wang Man-Man Zhang Bo Yang Source Type: research

What is the Price of the Potential for a Meaningful Recovery following Intracerebral Hemorrhage?
In this issue of the Journal of Stroke and Cerebrovascular Diseases, Vardanyan and colleagues report on the cost-utility of minimally invasive surgery (MIS) with thrombolysis for spontaneous intracerebral hemorrhage (ICH) from the perspective of the United Kingdom (UK) National Health Service (NHS)1 using data from the Minimally Invasive Surgery Plus Alteplase in Intracerebral Hemorrhage Evacuation (MISTIE III) trial2 and the UK Sentinel Stroke National Audit Programme (SSNAP).3 The economic evaluation revealed that the incremental cost-effectiveness ratio for MIS with thrombolysis fell significantly above the UK's Nationa...
Source: Journal of Stroke and Cerebrovascular Diseases - July 27, 2021 Category: Neurology Authors: Lourdes R. Carhuapoma, Avni Kapadia, Henry A. Glick, Daniel F. Hanley Source Type: research

Non-alcoholic beverages intake and risk of cardiovascular disease among Japanese men and women: the JPHC study
In conclusion, the risks of stroke and total cardiovascular disease were lower with a higher intake of non-alcoholic beverages in Japanese men and women.PMID:34284829 | DOI:10.1017/S0007114521002737
Source: The British Journal of Nutrition - July 21, 2021 Category: Nutrition Authors: Renzhe Cui Hiroyasu Iso Ehab S Eshak Koutatsu Maruyama Junko Ishihara Ribeka Takachi Norie Sawada Shoichiro Tsugane JPHC Study Group Source Type: research

Acupuncture inhibits mammalian target of rapamycin, promotes autophagy and attenuates neurological deficits in a rat model of hemorrhagic stroke
CONCLUSION: Acupuncture improved neurological deficits in a rat model of ICH, possibly by inhibiting the mTOR pathway and activating autophagy.PMID:34284645 | DOI:10.1177/09645284211028873
Source: Acupuncture in Medicine : journal of the British Medical Acupuncture Society - July 21, 2021 Category: Complementary Medicine Authors: Hao Liu Beng Zhang Xin-Wei Li Jia Du Pei-Pei Feng Chen Cheng Zhong-Hua Zhu Ke-Lang Lou Chen Ruan Chi Zhou Xiao-Wei Sun Source Type: research

Sleep and physical activity in relation to all-cause, cardiovascular disease and cancer mortality risk
CONCLUSION: The detrimental associations of poor sleep with all-cause and cause-specific mortality risks are exacerbated by low PA, suggesting likely synergistic effects. Our study supports the need to target both behaviours in research and clinical practice.PMID:34187783 | DOI:10.1136/bjsports-2021-104046
Source: British Journal of Sports Medicine - June 30, 2021 Category: Sports Medicine Authors: Bo-Huei Huang Mitch J Duncan Peter A Cistulli Natasha Nassar Mark Hamer Emmanuel Stamatakis Source Type: research

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