Filtered By:
Specialty: Allergy & Immunology
Condition: Ischemic Stroke
This page shows you your search results in order of date.
Order by Relevance | Date
Total 407 results found since Jan 2013.
TMAO Promotes NLRP3 Inflammasome Activation of Microglia Aggravating Neurological Injury in Ischemic Stroke Through FTO/IGF2BP2
Source: Journal of Inflammation Research - August 28, 2023 Category: Allergy & Immunology Tags: Journal of Inflammation Research Source Type: research
The Association of the Neutrophil-to-Lymphocyte Ratio, Platelet-to-Lymphocyte Ratio, Lymphocyte-to-Monocyte Ratio and Systemic Inflammation Response Index with Short-Term Functional Outcome in Patients with Acute Ischemic Stroke
Source: Journal of Inflammation Research - August 23, 2023 Category: Allergy & Immunology Tags: Journal of Inflammation Research Source Type: research
Tregs depletion aggravates activation of astrocytes by modulating IL-10/GXP4 following cerebral infarction
ConclusionTregs depletion attenuates renal fibrosis by modulating IL-10/GPX4 following cerebral infarction.
Source: Frontiers in Immunology - August 9, 2023 Category: Allergy & Immunology Source Type: research
Revisiting the role of the complement system in intracerebral hemorrhage and therapeutic prospects
Int Immunopharmacol. 2023 Aug 6;123:110744. doi: 10.1016/j.intimp.2023.110744. Online ahead of print.ABSTRACTIntracerebral hemorrhage (ICH) is a stroke subtype characterized by non-traumatic rupture of blood vessels in the brain, resulting in blood pooling in the brain parenchyma. Despite its lower incidence than ischemic stroke, ICH remains a significant contributor to stroke-related mortality, and most survivors experience poor outcomes that significantly impact their quality of life. ICH has been accompanied by various complex pathological damage, including mechanical damage of brain tissue, hematoma mass effect, and th...
Source: International Immunopharmacology - August 8, 2023 Category: Allergy & Immunology Authors: Yuanyuan Li Chenxi Tao Na An Haoqi Liu Zhenhong Liu Hongrui Zhang Yikun Sun Yanwei Xing Yonghong Gao Source Type: research
A Narrative Review of the Neurological Manifestations of Human Adenosine Deaminase 2 Deficiency
AbstractDeficiency of human adenosine deaminase type 2 (DADA2) is a complex systemic autoinflammatory disorder characterized by vasculopathy, immune dysregulation, and hematologic abnormalities. The most notable neurological manifestations of DADA2 are strokes that can manifest with various neurological symptoms and are potentially fatal. However, neurological presentations can be diverse. We here present a review of the neurological manifestations of DADA2 to increase clinical awareness of DADA2 as the underlying diagnosis. We reviewed all published cases of DADA2 from 1 January 2014 until 19 July 2022 found via PubMed. A...
Source: Journal of Clinical Immunology - August 7, 2023 Category: Allergy & Immunology Source Type: research
Association Between Inflammatory Burden Index and Unfavorable Prognosis After Endovascular Thrombectomy in Acute Ischemic Stroke
Source: Journal of Inflammation Research - July 19, 2023 Category: Allergy & Immunology Tags: Journal of Inflammation Research Source Type: research
Macrophage and monocyte subsets in response to ischemic stroke
This article is protected by copyright. All rights reserved.PMID:37467166 | DOI:10.1002/eji.202250233
Source: European Journal of Immunology - July 19, 2023 Category: Allergy & Immunology Authors: Nelli Blank-Stein Elvira Mass Source Type: research
Kidney function and cardiovascular diseases: a large-scale observational and Mendelian randomization study
ConclusionOur study provides evidence for causal effects of CVDs on kidney function. However, the evidence to support the causal effects of kidney function on CVDs is currently insufficient. Further mechanistic studies are required to determine the causality.
Source: Frontiers in Immunology - July 17, 2023 Category: Allergy & Immunology Source Type: research
TNF- α evokes blood-brain barrier dysfunction through activation of Rho-kinase and neurokinin 1 receptor
In conclusion, specific inhibition of Rho kinase in cerebrovascular conditions, accompanied by excessive release of pro-inflammatory cytokine TNF-α, helps preserve endothelial cell morphology and inter-endothelial cell barrier formation and may serve as an important therapeutic target.PMID:37454559 | DOI:10.1016/j.imbio.2023.152706
Source: Immunobiology - July 16, 2023 Category: Allergy & Immunology Authors: Xin Gao Ulvi Bayraktutan Source Type: research
Pharmacological Upregulation of Microglial Lipid Droplet Alleviates Neuroinflammation and Acute Ischemic Brain Injury
In this study, we observed increased LDs accumulation in microglia at the acute stage of ischemic stroke by immunofluorescence and flow cytometry. Transcriptomic analysis indicated that microglia accumulated with LDs were associated with inflammation and phagocytosis. Both inflammatory activation and phagocytosis of tissue debris in microglia could contribute to LDs formation. Moreover, through specific LDs depletion and overload experiments by pharmacological approaches, we proposed that LDs was critical for the maintenance of anti-inflammatory properties of microglia. Furthermore, Atglistatin, a specific adipose triglyce...
Source: Inflammation - July 14, 2023 Category: Allergy & Immunology Source Type: research
Increased Serum Levels of IL-1 β after Ischemic Stroke are Inversely Associated with Vitamin D
CONCLUSION: Ischemic stroke correlates positively with IL-1β and negatively with VitD levels. The speculated role of VitD deficiency in the evolution and severity of stroke may be justified by its role in the modification of inflammation.PMID:37431715 | DOI:10.22034/iji.2023.96384.2432
Source: Iranian Journal of Immunology - July 11, 2023 Category: Allergy & Immunology Authors: Mahnaz Bayat Niloufar Razavi Moosavi Najmeh Karimi Moosa Rahimi Afshin Borhani-Haghighi Source Type: research
The impact of fingolimod on Treg function in brain ischaemia
In conclusion, fingolimod seems to improve the suppressive function of Treg post-stroke while also increasing the resistance of CD4+ effector cells to this suppression. Fingolimod's capacity to increase both effector and regulatory functions may explain the lack of consistent improvement in functional recovery in experimental brain ischaemia.PMID:37366289 | DOI:10.1002/eji.202350370
Source: European Journal of Immunology - June 27, 2023 Category: Allergy & Immunology Authors: Kyle Malone Jennifer A Shearer Christian Waeber Anne C Moore Source Type: research
