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Condition: Ischemic Stroke
Procedure: Carotid Endarterectomy

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Total 922 results found since Jan 2013.

Low Incidence of Late Ipsilateral Ischaemic Stroke After Treatment for Symptomatic Carotid Stenosis in Sweden 2008-2017: Increased Risk in the Elderly and After Carotid Stenting
CONCLUSION: The incidence of ipsilateral IS after treatment for symptomatic carotid stenosis in Sweden 2008-2017 was low, demonstrating the effectiveness and durability of surgery in a real world setting. Only age above 80 years and CAS compared with CEA were associated with increased risk of ipsilateral IS.PMID:34794877 | DOI:10.1016/j.ejvs.2021.09.019
Source: PubMed: Eur J Vasc Endovasc ... - November 19, 2021 Category: Surgery Authors: Kimberley Hammar Ann Charlotte Laska Per Wester Kevin Mani Annika Lundstr öm Magnus Jonsson Source Type: research

Neurologic Outcomes of Carotid and Other Emergent Interventions for Ischemic Stroke Over 6  Years With Analysis Enhanced by Machine Learning
Despite continued evolution in treatment, stroke continues to represent one of the most common and debilitating diseases patients suffer. We created a novel machine-learning natural language processing algorithm to assist in performing outcomes research for patients undergoing treatment for stroke. This method enhanced our ability to accurately determine neurologic outcomes for all urgent stroke interventions. Results demonstrate stroke severity and functional neurologic outcomes for all ischemic stroke patients undergoing (1) urgent carotid endarterectomy (uCEA)/urgent carotid artery stenting (uCAS), (2) tissue plasminoge...
Source: Journal of Vascular Surgery - December 20, 2021 Category: Surgery Authors: P. Andrew Rivera, Bethany Jennings, Jeff Burton, Aaron Hayson, Faith Mason, Jaron Pettis, Adam Berenson, W.C. Sternbergh, Samuel Money, Daniel Fort, Hernan Bazan Source Type: research

A comparative effectiveness study of carotid intervention for long-term stroke prevention in patients with severe asymptomatic stenosis from a large integrated health system
CONCLUSIONS: In this contemporary cohort study of patients with ACS utilizing rigorous analytic methodology, CEA appears to have a small but statistically significant effect on stroke prevention out to 8 years. Further study is needed to appropriately select the subset of patients most likely to benefit from intervention.PMID:37406943 | DOI:10.1016/j.jvs.2023.06.024
Source: Atherosclerosis - July 5, 2023 Category: Cardiology Authors: Robert W Chang Noel Pimentel Lue-Yen Tucker Kara A Rothenberg Andrew L Avins Alexander C Flint Rishad M Faruqi Mai N Nguyen-Huynh Romain Neugebauer Source Type: research

Plaque At RISK (PARISK): prospective multicenter study to improve diagnosis of high‐risk carotid plaques
BackgroundPatients with symptomatic carotid artery stenosis are at high risk for recurrent stroke. To date, the decision to perform carotid endarterectomy in patients with a recent cerebrovascular event is mainly based on degree of stenosis of the ipsilateral carotid artery. However, additional atherosclerotic plaque characteristics might be better predictors of stroke, allowing for more precise selection of patients for carotid endarterectomy. Aims and hypothesisWe investigate the hypothesis that the assessment of carotid plaque characteristics with magnetic resonance imaging, multidetector‐row computed tomography angio...
Source: International Journal of Stroke - October 1, 2013 Category: Neurology Authors: M. T. B. Truijman, M. E. Kooi, A. C. Dijk, A. A. J. Rotte, A. G. Kolk, M. I. Liem, F. H. B. M. Schreuder, E. Boersma, W. H. Mess, R. J. Oostenbrugge, P. J. Koudstaal, L. J. Kappelle, P. J. Nederkoorn, A. J. Nederveen, J. Hendrikse, A. F. W. Steen, M. J. A Tags: Research Source Type: research

Safety of carotid endarterectomy following thrombolysis for acute ischemic stroke
Conclusions: Despite slightly higher rates of postoperative hemorrhagic strokes than those in randomized trials, CEA appears safe following thrombolysis for acute ischemic stroke. However, more data on the timing of surgery is needed.
Source: Journal of Vascular Surgery - July 29, 2013 Category: Surgery Authors: Yao Pey Yong, John Saunders, Said Abisi, Nikola Sprigg, Krishna Varadhan, Shane MacSweeney, Nishath Altaf Tags: Review articles Source Type: research

Prediction of recurrent stroke with ABCD2 and ABCD3 scores in patients with symptomatic 50-99% carotid stenosis
Background: Although it is preferable that all patients with a recent Transient Ischemic Attack (TIA) undergo acute carotid imaging, there are centers with limited access to such acute examinations. It is controversial whether ABCD2 or ABCD3 scores can be used to triage patients to acute or delayed carotid imaging. It would be acceptable that some patients with a symptomatic carotid stenosis are detected with a slight delay as long as those who will suffer an early recurrent stroke are detected within 24?hours. The aim of this study is to analyze the ability of ABCD2 and ABCD3 scores to predict ipsilateral ischemic stroke ...
Source: BMC Neurology - November 30, 2014 Category: Neurology Authors: Elias JohanssonJakob BjellerupPer Wester Source Type: research

Life‐threatening coronary disease is prevalent in patients with stenosing carotid artery disease
ConclusionsEndarterectomized carotid patients have a high risk of acute myocardial infarction and death, and need an intensified cardiovascular disease‐risk‐lowering treatment. Although asymptomatic, the evaluation of prognostically significant myocardial ischemia should be considered in these high‐risk patients. Eventually, a clinical trial is needed to address whether carotid patients would benefit from early intervention.
Source: International Journal of Stroke - August 26, 2015 Category: Neurology Authors: Krista Nuotio, Lauri Soinne, Helena Hänninen, Jani Saksi, Jarno Tuimala, Antti Jula, Petri T. Kovanen, Markku Kaste, Petra Ijäs, Perttu J. Lindsberg Tags: Research Source Type: research

Natural History of Extracranial Carotid Stenosis in Asian Stroke Patients- A Retrospective Study (P1.182)
Conclusions- Symptomatic steno-occlusive disease of cervical carotid artery carries a high risk of subsequent vascular events and mortality despite best medical therapy. Perhaps, better methods of risk stratification and an aggressive approach towards revascularisation in eligible cases are warranted.Disclosure: Dr. Chandra has nothing to disclose. Dr. Woo has nothing to disclose. Dr. Woo has nothing to disclose. Dr. Liu has nothing to disclose. Dr. Kulkarni has nothing to disclose. Dr. Sharma has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Chandra, B., Woo, J. W., Woo, R. W., Liu, R. J., Kulkarni, A., Sharma, V. Tags: Cerebrovascular Disease: Risk Factors and Prevention Source Type: research

Life ‐threatening coronary disease is prevalent in patients with stenosing carotid artery disease
ConclusionsEndarterectomized carotid patients have a high risk of acute myocardial infarction and death, and need an intensified cardiovascular disease‐risk‐lowering treatment. Although asymptomatic, the evaluation of prognostically significant myocardial ischemia should be considered in these high‐risk patients. Eventually, a clinical trial is needed to address whether carotid patients would benefit from early intervention.
Source: International Journal of Stroke - August 25, 2015 Category: Neurology Authors: Krista Nuotio, Lauri Soinne, Helena H änninen, Jani Saksi, Jarno Tuimala, Antti Jula, Petri T. Kovanen, Markku Kaste, Petra Ijäs, Perttu J. Lindsberg Tags: Research Source Type: research

Safety of urgent endarterectomy in acute non ‐disabling stroke patients with symptomatic carotid artery stenosis: an international multicenter study
ConclusionsOur findings highlight that urgent CEA performed within two days from the index event is related to a non ‐significant increase in the risk of peri‐procedural stroke. The safety of urgent CEA requires further evaluation in larger datasets.This article is protected by copyright. All rights reserved.
Source: European Journal of Neurology - November 25, 2018 Category: Neurology Authors: Andromachi Roussopoulou, Georgios Tsivgoulis, Christos Krogias, Andreas Lazaris, Konstantinos Moulakakis, George S. Georgiadis, Robert Mikulik, John D. Kakisis, Christina Zompola, Simon Faissner, Maria Chondrogianni, Chrissoula Liantinioti, Th Tags: Original Article Source Type: research

Timing of procedural stroke and death in asymptomatic patients undergoing carotid endarterectomy: individual patient analysis from four RCTs.
CONCLUSION: At least half of the procedural strokes in this study were ischaemic and ipsilateral to the treated artery. Half of all procedural complications occurred on the day of surgery, but one-third after day 3 when many patients had been discharged. PMID: 32162310 [PubMed - as supplied by publisher]
Source: The British Journal of Surgery - March 11, 2020 Category: Surgery Authors: Poorthuis MHF, Bulbulia R, Morris DR, Pan H, Rothwell PM, Algra A, Becquemin JP, Bonati LH, Brott TG, Brown MM, Calvet D, Eckstein HH, Fraedrich G, Gregson J, Greving JP, Hendrikse J, Howard G, Jansen O, Mas JL, Lewis SC, de Borst GJ, Halliday A, Carotid Tags: Br J Surg Source Type: research

Neurologic outcomes of carotid and other emergent interventions for ischemic stroke over six years with dataset enhanced by machine learning
Current mainstays of ischemic stroke treatment include the use of thrombolysis (tissue plasminogen activator, tPA), urgent carotid endarterectomy (uCEA) or carotid artery stenting (uCAS), and mechanical endovascular reperfusion/thrombectomy (MER). Scarce data describe the presenting stroke severity and neurologic outcomes for these acute ischemic stroke interventions, alone or in combination. The authors hypothesize that patients undergoing carotid interventions experience better functional neurologic outcomes than other stroke interventions.
Source: Journal of Vascular Surgery - June 24, 2022 Category: Surgery Authors: P. Andrew Rivera, Jeffrey Burton, Aaron Hayson, Bethany Jennings, Gabriel Vidal, W.C. Sternbergh, Daniel Fort, Hernan A. Bazan Source Type: research

Neurologic outcomes of carotid and other emergent interventions for ischemic stroke over 6  years with dataset enhanced by machine learning
The current mainstays of ischemic stroke treatment include the use of thrombolysis (tissue plasminogen activator [tPA]), urgent carotid endarterectomy (uCEA) or urgent carotid artery stenting (uCAS), and mechanical endovascular reperfusion/thrombectomy (MER). Scarce data describe the presenting stroke severity and neurologic outcomes for these acute ischemic stroke interventions, alone or in combination. The authors hypothesize that patients undergoing carotid interventions experience better functional neurologic outcomes than other stroke interventions.
Source: Journal of Vascular Surgery - June 24, 2022 Category: Surgery Authors: P. Andrew Rivera, Jeffrey Burton, Aaron Hayson, Bethany Jennings, Gabriel Vidal, Waldemar C. Sternbergh, Daniel Fort, Hernan A. Bazan Source Type: research

Management of extracranial carotid artery stenosis during endovascular treatment for acute ischaemic stroke: results from the MR CLEAN Registry
CONCLUSIONS: Functional outcomes were comparable after EVT with and without CAS. CAS during EVT might be a feasible option to treat the extracranial ICA stenosis but randomised studies are warranted to prove non-inferiority or superiority.PMID:36572506 | DOI:10.1136/svn-2022-001891
Source: Atherosclerosis - December 26, 2022 Category: Cardiology Authors: Sabine L Collette Michael P Rodgers Marianne A A van Walderveen Kars C J Compagne Paul J Nederkoorn Jeannette Hofmeijer Jasper M Martens Gert J de Borst Gert Jan R Luijckx Charles B L M Majoie Aad van der Lugt Reinoud P H Bokkers Maarten Uyttenboogaart MR Source Type: research