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Condition: Ischemic Stroke
Infectious Disease: Chagas Disease

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Total 27 results found since Jan 2013.

Analysis of Risk Factors for In-Hospital Stroke Mortality and Stroke Readmission in Hospital Risoleta Tolentino Neves (HRTN) - Belo Horizonte, Brazil (P1.213)
Conclusions: This study identified previous history of AF, cardiopathy and diabetes as risk-factors for increased stroke in-hospital mortality. We also identified that cardioembolic stroke, previous Chagas' disease and prosthetic heart valve increased the risk of readmission.Disclosure: Dr. Meira has nothing to disclose. Dr. Dorim has nothing to disclose. Dr. Andrade has nothing to disclose. Dr. Santos has nothing to disclose. Dr. Magalhães has nothing to disclose. Dr. Ladeia has nothing to disclose. Dr. Tavares has nothing to disclose. Dr. Xavier has nothing to disclose. Dr. Tanure has nothing to disclose. Dr. Sant...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Meira, F., Dorim, D., Andrade, A. C., Santos, T., Magalhaes, D., Ladeia, L., Tavares, R., Xavier, R., Tanure, M., Santanna, R. Tags: Re-admission and Stroke Outcomes Source Type: research

Chagas Disease and Stroke: Frequency and Clinical Correlates (P3.235)
Conclusions: Patients presenting with stroke and CD had more cardiac impairment and cardioembolic events than non-CD patients. Better healthcare of stroke patients and CD is required as these patients were readmitted more frequently than those without CDDisclosure: Dr. Meira has nothing to disclose. Dr. Teixeira has nothing to disclose. Dr. Nunes has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Meira, F., Teixeira, A., Nunes, M. d. C. Tags: Stroke in the Young Source Type: research

Etiological Classification of Stroke in Patients with Chagas Disease Using TOAST, Causative Classification System TOAST, and ASCOD Phenotyping
Cardioembolism is considered a major pathophysiological mechanism in patients with ischemic stroke (IS) and Chagas disease (CD). However, a previous study reported that other stroke subtypes are present in more than 40% of CD patients according to the TOAST classification. Therefore, the aim of our study was to evaluate the etiologic classification of stroke in patients with CD using the Causative Classification System (CCS), the ASCOD, and the TOAST classifications in a prospective cohort of patients.
Source: Journal of Stroke and Cerebrovascular Diseases - August 22, 2017 Category: Neurology Authors: Rodrigo de Paiva Bezerra, Maram élia Araújo de Miranda Alves, Adriana Bastos Conforto, Daniela Laranja Gomes Rodrigues, Gisele Sampaio Silva Source Type: research

Artificial Inteligence-Based Decision for the Prediction of Cardioembolism in Patients with Chagas Disease and Ischemic Stroke
Chagas disease (CD) and ischemic stroke (IS) have a close, but poorly understood, association. There is paucity of evidence on the ideal secondary prophylaxis and etiological determination, with few cardioembolic patients being identified.
Source: Journal of Stroke and Cerebrovascular Diseases - August 13, 2021 Category: Neurology Authors: Vin ícius Viana Abreu Montanaro, Thiago Falcão Hora, Agostinho Alencar Guerra, Gisele Sampaio Silva, Rodrigo de Paiva Bezerra, Jamary Oliveira-Filho, Leila Souza Brito Santos, Eduardo Sousa de Melo, Luciana Patrizia Alves de Andrade, Wilson Alves de Oli Source Type: research

Ischemic stroke classification and risk of embolism in patients with Chagas disease
AbstractIschemic stroke (IS) and Chagas disease are strongly related. Nevertheless, little attention has been paid to this association and its natural history. The current guidelines concerning the management and secondary prevention of IS are largely based on the incomplete information or extrapolation of knowledge from other stroke etiologies. We performed a retrospective study which compared stroke etiologies among a cohort of hospitalized patients with IS and Chagas disease. The Instituto de Pesquisa Evandro Chagas/Funda ção Oswaldo Cruz (IPEC/FIOCRUZ) embolic score was also used to identify and evaluate the risk of ...
Source: Journal of Neurology - September 12, 2016 Category: Neurology Source Type: research

Ischemic stroke and infectious diseases in low-income and middle-income countries
Purpose of review To address the important relationships between stroke and infection, focusing on the most frequent infections found in low-income and middle-income countries. Recent findings Stroke is one of the leading causes of mortality and disability worldwide, with a great proportion of the stroke burden occurring in low-income and middle-income countries. Infectious diseases are still a great health problem in developing countries and it is possible that the proportion of infection-related strokes is greater in these nations. Infectious diseases and stroke have a bidirectional relationship. Common infections m...
Source: Current Opinion in Neurology - January 13, 2019 Category: Neurology Tags: CEREBROVASCULAR DISEASE: Edited by Didier Leys Source Type: research

Safety of IV thrombolysis in acute ischemic stroke related to Chagas disease
Conclusion: In the largest published series of patients with CD-related stroke treated with IV TPA, we have observed that IV thrombolysis was safely performed and showed no increase of SIH. The diagnosis of CD should not preclude IV thrombolysis in these patients.
Source: Neurology - November 11, 2013 Category: Neurology Authors: Cougo-Pinto, P. T., dos Santos, B. L., Dias, F. A., Camilo, M. R., Alessio-Alves, F. F., Barreira, C. M. A., Santos-Pontelli, T. E. G., Abud, D. G., Leite, J. P., Pontes-Neto, O. M. Tags: Parasitic infections, Clinical trials Observational study (Cohort, Case control), Cardiac, Embolism, Infarction ARTICLE Source Type: research

Mortality and Stroke Recurrence in a Rehabilitation Cohort of Patients with Cerebral Infarcts and Chagas Disease
Conclusions: Cardiac conditions did not correlate with mortality or recurrence. Age was a protective factor against recurrence, probably due to cumulative risk of IS over time, while initial mRS was associated with both outcomes. Treating diseases such as DM and bladder dysfunction, and early treatment to reduce the initial mRS could potentially prevent both outcomes; also, establishing a correct etiological diagnosis is important.Eur Neurol 2018;79:177 –184
Source: European Neurology - March 14, 2018 Category: Neurology Source Type: research

Inflammation Enhances the Risks of Stroke and Death in Chronic Chagas Disease Patients
This study provides a better understanding of the stroke pathobiology in the general population and might aid the development of therapeutic strategies for controlling the morbidity and mortality of Chagas disease.
Source: PLoS Neglected Tropical Diseases - April 25, 2016 Category: Tropical Medicine Authors: Paulo Marcos Matta Guedes Source Type: research

Anticoagulation in patients with cardiac manifestations of Chagas disease and cardioembolic ischemic stroke
Conclusion Patients with Chagas disease an d previous CIS had better control of INR with a higher frequency of minor bleeding.RESUMO Objetivos descrever as caracter ísticas da anticoagulação em pacientes com manifestações cardíacas da doença de Chagas (MCDC) e comparar os participantes com sem acidente vascular cerebral isquêmico cardioembólico (AVCIC). Resultados 42 pacientes com MCDC em anticoagulação foram estudados (62,9 ± 12,4 anos), 59,5% do sexo feminino e 47,6% com AVCIC prévio, 78,6% portadores de fibrilação atrial não valvar e 69,7% com cardiomiopatia dilatada. Varfarina foi utilizada em 78,6% dos...
Source: Arquivos de Neuro-Psiquiatria - January 22, 2018 Category: Neurology Source Type: research

Tissue Inhibitor of Metalloproteinase-1 Is Increased in Chagasic Cardiomyopathy
Am J Trop Med Hyg. 2021 Jul 19:tpmd200401. doi: 10.4269/ajtmh.20-0401. Online ahead of print.ABSTRACTChagas disease (CD) mainly conveys stroke risk through structural cardiac disease. However, stroke and cognitive impairment are seen in CD independently of cardiac disease severity. Chronic inflammation may be an explanation for this association, because inflammation plays an important role in the pathogenesis of acute ischemic stroke and dementia. In the present study, we selected five candidate biomarkers for Chagas disease: interleukin-6, membrane metalloproteinase-9, tissue inhibitor of metalloproteinase-1 (TIMP1), oros...
Source: The American Journal of Tropical Medicine and Hygiene - July 19, 2021 Category: Tropical Medicine Authors: Karina Oliveira Garcia Thiago Cerqueira Silva Maria do Carmo Pereira Nunes Iuri Ferreira Felix Murilo Araujo Oliveira Maria Eduarda Lisboa Marques Leila Souza Brito Santos Paulo Roberto Sampaio Peixoto Sousa Pedro Jos é Ramiro Muiños Renata Martins Maia Source Type: research