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Specialty: Neurology
Condition: Ischemic Stroke
Education: Study
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Total 11683 results found since Jan 2013.
Vasoprotective Effects of Hyperoside against Cerebral Ischemia/Reperfusion Injury in Rats: Activation of Large-Conductance Ca < sup > 2+ < /sup > -Activated K < sup > + < /sup > Channels
Neural Plast. 2023 Aug 14;2023:5545205. doi: 10.1155/2023/5545205. eCollection 2023.ABSTRACTHyperoside (Hyp), a kind of Chinese herbal medicine, exerts multiple therapeutic effects on many diseases. However, the role and mechanisms of Hyp in vascular pathophysiology in ischemic stroke need to be further established. The study aimed to investigate the role of (large-conductance Ca2+-activated K+) BK channels on the vasoprotection of Hyp against cerebral ischemia and reperfusion (I/R) injury in rats. The concentration gradient of Hyp was pretreated in both the middle cerebral artery occlusion and reperfusion model and oxygen...
Source: Neural Plasticity - August 23, 2023 Category: Neurology Authors: Wen-Ming Hong Yue-Wu Xie Meng-Yu Zhao Tian-Hang Yu Li-Na Wang Wan-Yan Xu Shen Gao Hua-Bao Cai Yan Guo Fang Zhang Source Type: research
Amantadine for NeuroenhaNcement in acutE patients Study - a protocol for a prospective pilot proof of concept phase IIb study in intensive and intermediate care unit patients (ANNES)
Persisting coma is a common complication in (neuro)intensive care in neurological disease such as acute ischemic stroke, intracerebral hemorrhage or subarachnoid hemorrhage. Amantadine acts as a nicotinic rece...
Source: BMC Neurology - August 22, 2023 Category: Neurology Authors: Anna Hofmann, Corinna Blum, Constanze Single, Kamal Adeyemi, Patricia Schwarz, Vasileios Siokas, Tim W. Rattay, Helene A. H äberle, Reimer Riessen, Bettina Brendel, Iris Haug, Ruth Bösel, Manola Zago, Peter Martus, Ulf Ziemann, Annerose Mengel & hellip; Tags: Study Protocol Source Type: research
Association of remnant cholesterol with intracranial atherosclerosis in community-based population: The ARIC study
Intracranial atherosclerotic stenosis (ICAS) is one of the main prevalent causes of ischemic stroke globally.1,2 However, even with aggressive medical management, the annual rate of stroke recurrence remains high among individuals with multiple risk factors and severe stenosis.2 Moreover, ICAS has been connected to an elevated risk of mild cognitive impairment and dementia3, which confers an extra necessity for the identification of risk factors associated with ICAS.
Source: Journal of Stroke and Cerebrovascular Diseases - August 19, 2023 Category: Neurology Authors: Peng Zhang, Ziheng Zhang, Daojing Li, Rongrong Han, Hongfang Li, Jinfeng Ma, Peng Xu, Ziyou Qi, Lixia Liu, Aimei Zhang Source Type: research
Thrombolysis and thrombectomy for stroke in octogenarians and nonagenarians: A regional observational study
DISCUSSION: IVT and MT improve early neurological recovery and functional outcome at discharge of both octogenarians and nonagenarians in current practice. Despite a poorer outcome for nonagenarians than octogenarians, these reperfusion treatments should not be withheld on the basis of age only.PMID:37596186 | DOI:10.1016/j.neurol.2023.03.023
Source: Revue Neurologique - August 18, 2023 Category: Neurology Authors: M Michelard O Detante O Heck S Marcel W Vadot G Gavazzi J Papassin Source Type: research
Surgery for Malignant Acute Ischemic Stroke: A Narrative Review of the Knowns and Unknowns
Semin Neurol 2023; 43: 370-387 DOI: 10.1055/s-0043-1771208Malignant acute ischemic stroke (AIS) is characterized by acute neurological deterioration caused by progressive space-occupying brain edema, often occurring in the first hours to days after symptom onset. Without any treatment, the result is often fatal. Despite advances in treatment for AIS, up to 80% of patients with a large hemispheric stroke or cerebellar stroke are at risk of poor outcome. Decompressive surgery can be life-saving in a subgroup of patients with malignant AIS, but uncertainties exist on patient selection, predictors of malignant infarction, peri...
Source: Seminars in Neurology - August 18, 2023 Category: Neurology Authors: Krishnan, Kailash Hollingworth, Milo Nguyen, Thanh N. Kumaria, Ashwin Kirkman, Matthew A. Basu, Surajit Tolias, Christos Bath, Philip M. Sprigg, Nikola Tags: Review Article Source Type: research
The influence of COVID-19 on the treatment of patients with acute ischemic stroke: a retrospective observational study
CONCLUSIONS: The pandemic situation of COVID-19 significantly reduced the number of patients with AIS and prolonged the travel time to the hospital whereas most of the stroke treatment services were maintained.PMID:37587891 | DOI:10.5114/fn.2023.124565
Source: Folia Neuropathologica - August 17, 2023 Category: Neurology Authors: Wei Chen Fangju Lin Wei Zhao Baoling Yang Weihua Jia Source Type: research
