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P089/268 Safety and efficacy of the fourth-generation Acandis Acclino Flex Plus stent in managing complex intracranial aneurysms
ConclusionThe AFP stent demonstrated feasibility and favourable safety and efficacy in the treatment of complex aneurysms. These results support its clinical use and highlight the need for further studies to evaluate its performance in different aneurysm subsets and to determine its specific role in the endovascular treatment of aneurysms.Disclosure of InterestCK serves as consultants for Acandis GmbH (Pforzheim, Germany) and proctor for MicroVention Inc./Sequent Medical (Aliso Viejo, CA, USA). David Zopfs is on the speaker’s bureau of Philips (Amsterdam, the Netherlands) and lecturer for Amboss GmbH (Cologne, Germany).
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Goertz, L., Zopfs, D., Schönfeld, M., Schlamann, M., Kabbasch, C. Tags: 1.1 HAEMORRHAGIC - Aneurysms Source Type: research

P090/269 Comparative analysis between a second-generation (acandis acclino) and a first-generation (enterprise) stent system
ConclusionAdvanced stents offer reduced thromboembolic risk and comparable aneurysm occlusion to first-generation stents due to their flexible design and surface modification. These results support the clinical use of advanced stent systems, but further comparative studies are needed to conclusively evaluate the efficacy of stent-assisted coiling with the Acclino stent and other systems.Disclosure of InterestCK serves as consultants for Acandis GmbH (Pforzheim, Germany) and proctor for MicroVention Inc./Sequent Medical (Aliso Viejo, CA, USA). David Zopfs is on the speaker’s bureau of Philips (Amsterdam, the Netherlan...
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Goertz, L., Zopfs, D., Schönfeld, M., Turowski, B., Schlamann, M., Kabbasch, C. Tags: 1.1 HAEMORRHAGIC - Aneurysms Source Type: research

In ischemic stroke, adding EVT to usual care at 6 to 24 h improved functional status at 90 d
Ann Intern Med. 2023 Jul 4. doi: 10.7326/J23-0050. Online ahead of print.ABSTRACTOlthuis SGH, Pirson FAV, Pinckaers FME, et al; MR CLEAN-LATE investigators. Endovascular treatment versus no endovascular treatment after 6-24 h in patients with ischaemic stroke and collateral flow on CT angiography (MR CLEAN-LATE) in the Netherlands: a multicentre, open-label, blinded-endpoint, randomised, controlled, phase 3 trial. Lancet. 2023;401:1371-1380. 37003289.PMID:37399551 | DOI:10.7326/J23-0050
Source: Annals of Internal Medicine - July 3, 2023 Category: Internal Medicine Authors: Barnet Eskin Source Type: research

Endovascular treatment for isolated posterior cerebral artery occlusion stroke in the MR CLEAN registry
Conclusions EVT should be considered in selected patients with AIS with an isolated PCA occlusion, presenting with moderate–severe neurological deficits, as EVT was technically feasible in most of our patients and about half had good clinical outcome. In case of lower NIHSS score, a more conservative approach seems warranted, since periprocedural complications are not uncommon. Nonetheless, EVT seems reasonably safe considering the absence of sICH in our study.
Source: Journal of NeuroInterventional Surgery - March 14, 2023 Category: Neurosurgery Authors: Brouwer, J., Ergezen, S., Mulder, M. J. H. L., Lycklama a Nijeholt, G. J., van Es, A. C. G. M., van der Lugt, A., Dippel, D. W. J., Majoie, C. B. L. M., Roos, Y. B. W. E. M., Coutinho, J. M., Emmer, B. J., on behalf of the MR CLEAN Registry investigators, Tags: Ischemic stroke Source Type: research

Etiology of Large Vessel Occlusion Posterior Circulation Stroke: Results of the MR CLEAN Registry
CONCLUSIONS: Unlike the anterior circulation, most frequent cause in our posterior large vessel occlusion stroke cohort is LAA followed by cardioembolism, dissection, and ESUS. Patients with cardioembolism and ESUS have a better prognosis for functional outcome after endovascular thrombectomy than patients with LAA.PMID:35543130 | DOI:10.1161/STROKEAHA.121.038054
Source: Atherosclerosis - May 11, 2022 Category: Cardiology Authors: F A V Anne Pirson Nikki Boodt Josje Brouwer Agnetha A E Bruggeman Wouter H Hinsenveld Julie Staals Wim H van Zwam Christiaan van der Leij Rutger J B Brans Charles B L M Majoie Diederik W J Dippel Aad van der Lugt Wouter J Schonewille Robert J van Oostenbr Source Type: research

Influence of Onset to Imaging Time on Radiological Thrombus Characteristics in Acute Ischemic Stroke
Conclusion: In our population of acute ischemic stroke patients, we found no clear association between onset-to-imaging time and radiological thrombus characteristics. This suggests that elapsed time from stroke onset plays a limited role in the interpretation of radiological thrombus characteristics and their effect on treatment results, at least in the early time window.
Source: Frontiers in Neurology - June 18, 2021 Category: Neurology Source Type: research

Prediction of long-term recurrent ischemic stroke: the added value of non-contrast CT, CT perfusion, and CT angiography
ConclusionData from CT imaging significantly improved the discriminatory performance and reclassification in predicting ischemic stroke recurrence beyond a model incorporating clinical risk factors only.
Source: Neuroradiology - March 17, 2021 Category: Radiology Source Type: research

Peripheral Artery Disease in Acute Ischemic Stroke Patients Treated With Endovascular Thrombectomy; Results From the MR CLEAN Registry
Conclusion: In the absence of an association between the presence of PAD and collateral scores or outcomes after EVT, it may be questioned whether PAD leads to RIPC in patients with acute ischemic stroke due to large vessel occlusion.
Source: Frontiers in Neurology - October 6, 2020 Category: Neurology Source Type: research

Radiology workload in clinical implementation of thrombectomy for acute ischemic stroke: experience from The Netherlands
ConclusionOur study estimated the number of stroke patients undergoing CTA for suspected LVO and those eligible for thrombectomy in relation to the population. Numbers were essentially the same throughout the week, and during office and on-call hours. Our data can be used to make adequate staffing plans.
Source: Neuroradiology - April 4, 2020 Category: Radiology Source Type: research

Blunt cerebrovascular injury: incidence and long-term follow-up
ConclusionsImproved CTA diagnostic modalities have increased BCVI incidence. Furthermore, BCVI patients reported significant functional impairment at long-term follow-up. Antiplatelet therapy showed a significant effect on in-hospital stroke rate reduction.
Source: European Journal of Trauma and Emergency Surgery - June 12, 2019 Category: Emergency Medicine Source Type: research

Correlation Between Intracranial Arterial Calcification and Imaging of Cerebral Small Vessel Disease
Conclusion: Intracranial artery calcification is common in patients with ischemic cerebrovascular disease and the intracranial carotid artery is most frequently affected. Intracranial arterial calcifications might be associated with imaging markers of SVD and are highly correlated with WMHs, lacunes, and CMBs. Quantification of calcification on CT provides additional information on the pathophysiology of SVD. Intracranial arterial calcification could act as a potential marker of SVD. Introduction Atherosclerosis is a systemic vascular process that is considered a major cause of cerebrovascular and cardiovascular di...
Source: Frontiers in Neurology - April 30, 2019 Category: Neurology Source Type: research

Multimodal Optical Diagnostics of the Microhaemodynamics in Upper and Lower Limbs
Conclusion The use of optical non-invasive diagnostic methods has a great potential for the detection of concomitant microcirculation disorders in patients with rheumatic diseases and diabetes. In this review, it was shown that the use of laser Doppler flowmetry, optical tissue oximetry and fluorescence spectroscopy together or separately may have important diagnostic value for the detection of violations, assessment of their severity, as well as for the analysis of the effectiveness of the therapy. The joint application of the considered technologies with the methods of machine learning (discriminant analysis) can be use...
Source: Frontiers in Physiology - April 15, 2019 Category: Physiology Source Type: research

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