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Condition: Epilepsy
Procedure: MRI Scan
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Total 1348 results found since Jan 2013.
Disruptions in modular structure and network integration of language-related network predict language performance in temporal lobe epilepsy: Evidence from graph-based analysis
Epilepsy Behav. 2023 Sep 7;147:109407. doi: 10.1016/j.yebeh.2023.109407. Online ahead of print.ABSTRACTOBJECTIVE: Temporal lobe epilepsy (TLE) is a network disorder that alters the total organization of the language-related network. Task-based functional magnetic resonance imaging (fMRI) aimed at functional connectivity is a direct method to investigate how the network is reorganized. However, such studies are scarce and represented mostly by the resting-state analysis of the individual connections between regions. To fill this gap, we used a graph-based analysis, which allows us to cover the total language-related network...
Source: Epilepsy and Behaviour - September 9, 2023 Category: Neurology Authors: Victor Karpychev Svetlana Malyutina Anna Zhuravleva Oleg Bronov Vasiliy Kuzin Aleksei Marinets Olga Dragoy Source Type: research
Seizure-induced reversible magnetic resonance imaging abnormalities: A retrospective cohort study
CONCLUSIONS: SRMA is an uncommon finding following seizures. It is not associated with poor seizure control or mortality. Risk factors associated with SRMA include older age and longer seizure duration including status epilepticus.PMID:37677903 | DOI:10.1016/j.yebeh.2023.109405
Source: Epilepsy and Behaviour - September 7, 2023 Category: Neurology Authors: Zhu Chung Che Frederick P Mariajoseph Daniel Saddik Shalini Amukotuwa Udaya Seneviratne Source Type: research
Autologous olfactory mucosa mesenchymal stem cells treatment improves the neural network in chronic refractory epilepsy
CONCLUSIONS: Autologous OM-MSC treatment is efficacious for improving chronic refractory epilepsy, suggesting a future therapeutic candidate for epilepsy.TRIAL REGISTRATION: The study was registered with Chinese Clinical Trial Registry (ChiCTR2200055357).PMID:37674249 | DOI:10.1186/s13287-023-03458-6
Source: Cell Research - September 6, 2023 Category: Cytology Authors: Zheng-Zhao Liu Yan Huang Chun-Gu Hong Xin Wang Ran Duan Jian-Yang Liu Jia-Lin He Da Duan Hui Xie Ming Lu Source Type: research
Divergent neurodevelopmental profiles of very-low-birth-weight infants
CONCLUSIONS: VLBWIs show a broad spectrum of neurodevelopmental outcomes after 6 years. These divergent profiles also indicate that different risks contribute to the development of ASD/ADHD from those of cerebral palsy and epilepsy in VLBWIs.IMPACT: Very-low-birth-weight infants (VLBWIs) show divergent neurodevelopmental outcomes from age 3 to 6 years. A deep longitudinal study depicts the dynamic change in neurodevelopmental profiles of VLBWIs from age 3 to 6 years. Perinatal brain injury is associated with developmental delay, cerebral palsy and epilepsy, but not with ASD or ADHD at age 6 years.PMID:37626120 | DOI:10.1038/s41390-023-02778-w
Source: Pediatric Research - August 25, 2023 Category: Pediatrics Authors: Reina Ogata Kyoko Watanabe Pin Fee Chong Jun Okamoto Yoshihiro Sakemi Toshinori Nakashima Takuro Ohno Hiroyuki Nomiyama Yuri Sonoda Yuko Ichimiya Hirosuke Inoue Masayuki Ochiai Hironori Yamashita Yasunari Sakai Shouichi Ohga Source Type: research
Clinical study of autonomic dysfunction in patients with autoimmune encephalitis
CONCLUSION: This study demonstrated the comparisons between autonomic dysfunction group and autonomic dysfunction-free group and provided insights into better diagnosis and treatment.PMID:37543010 | DOI:10.1016/j.imbio.2023.152711
Source: Immunobiology - August 5, 2023 Category: Allergy & Immunology Authors: Jiao He Yajun Lian Source Type: research
Altered white matter organization and its correlations with executive functioning among adolescents with epilepsy
Eur J Paediatr Neurol. 2023 Jul 23;46:82-88. doi: 10.1016/j.ejpn.2023.07.004. Online ahead of print.ABSTRACTDeficits in executive functions (EF) are a common comorbidity among adolescents with epilepsy. EF deficits were previously correlated with altered connectivity of the fronto-parietal and cingulo-opercular neural networks. The current study investigated white matter integrity in adolescents with epilepsy (n = 29) relative to healthy controls (n = 19). Participants completed questionnaires, neuropsychological testing, and brain magnetic resonance imaging (MRI) that included diffusion tensor imaging (DTI) sequences. On ...
Source: European Journal of Paediatric Neurology - August 4, 2023 Category: Neurology Authors: Dror Kraus Rola Farah Haya Fischer Jennifer Vannest Shari L Wade Rupa Radhakrishnan Avani C Modi Tzipi Horowitz-Kraus Source Type: research
Perampanel and lacosamide monotherapy in pediatric patients with newly diagnosed focal epilepsy: A prospective study evaluating efficacy, tolerability, and behavior
CONCLUSIONS: The present study documented similar good effectiveness and good tolerance of PER and LCM as monotherapy in pediatric patients with newly diagnosed focal epilepsy and showed no behavioral or emotional impact, as assessed by the CBCL. Though the incidence of irritability with PER monotherapy may be higher than that with LCM monotherapy soon after medication initiation, this side effect appears to resolve spontaneously within a few months. At present, this study was the first research about PER and LCM monotherapy in pediatric patients with newly diagnosed focal epilepsy evaluating efficacy, tolerability, and be...
Source: Epilepsy and Behaviour - July 23, 2023 Category: Neurology Authors: Rui Zhou Rui Qu Min Liu Dan-Ping Huang Jin-Yi Zhou Yan Chen Xu-Qin Chen Source Type: research
The role of the thalamus in modular functional networks in temporal lobe epilepsy with cognitive impairment
CONCLUSIONS: The thalamus plays a prominent role in modular networks and potentially represents a key neural mechanism underlying cognitive impairment in TLE.PMID:37424152 | DOI:10.1111/cns.14345
Source: CNS Neuroscience and Therapeutics - July 10, 2023 Category: Neuroscience Authors: Xiaomin Pang Xiulin Liang Weiwei Chang Zongxia Lv Jingyuan Zhao Peirong Wu Xinrong Li Wutong Wei Jinou Zheng Source Type: research
