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Condition: SARS
Nutrition: Zinc
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Total 237 results found since Jan 2013.
The Pathogenesis of COVID-19-Related Taste Disorder and Treatments
J Dent Res. 2023 Sep 20:220345231182926. doi: 10.1177/00220345231182926. Online ahead of print.ABSTRACTCOVID-19, mainly manifested as acute respiratory distress syndrome, has afflicted millions of people worldwide since 2019. Taste dysfunction is a common early-stage symptom of COVID-19 infection that burdens patients for weeks or even permanently in some cases. Owing to its subjectivity and complexity, the mechanism of taste disorder is poorly studied. Previous studies have reported that the COVID-19 entry receptors are highly expressed in taste buds, thereby intensifying the cytocidal effect. Taste receptor cells are vul...
Source: Cell Research - September 20, 2023 Category: Cytology Authors: J Wang R Liu H Ma W Zhang Source Type: research
The Possible Mechanisms of Cu and Zn in the Treatment and Prevention of HIV and COVID-19 Viral Infection
Biol Trace Elem Res. 2023 Aug 23. doi: 10.1007/s12011-023-03788-9. Online ahead of print.ABSTRACTDue to their unique properties and their potential therapeutic and prophylactic applications, heavy metals have attracted the interest of many researchers, especially during the outbreak of COVID-19. Indeed, zinc (Zn) and copper (Cu) have been widely used during viral infections. Zn has been reported to prevent excessive inflammatory response and cytokine storm, improve the response of the virus to Type I interferon (IFN-1), and enhance the production of IFN-a to counteract the antagonistic effect of SARS-CoV-2 virus protein on...
Source: Biological Trace Element Research - August 22, 2023 Category: Biology Authors: Shatha A Albalawi Raneem A Albalawi Amaal A Albalawi Raghad F Alanazi Raghad M Almahlawi Basma S Alhwity Bashayer D Alatawi Nehal Elsherbiny Saleh F Alqifari Mohamed S Abdel-Maksoud Source Type: research
Comparing solid-based concentration methods for rapid and efficient recovery of SARS-CoV-2 for wastewater surveillance
This study showed significant higher BCoV recovery and SARS-CoV-2 viral RNA in wastewater solid fraction (p = 0.006) than liquid fraction. Our result suggests that the solid fraction of wastewater samples is more suitable for recovering enveloped viruses from wastewater, and the DC and AHAP methods equally provide suitably rapid, cost-effective, and significantly higher recovery of SARS-CoV-2 viral RNA in wastewater samples.PMID:37558056 | DOI:10.1016/j.jviromet.2023.114790
Source: Journal of Virological Methods - August 9, 2023 Category: Virology Authors: Doris Yoong Wen Di Bo Li Min Ki Jeon Tao Yan Source Type: research
Comparing Solid-Based Concentration Methods for Rapid and Efficient Recovery of SARS-CoV-2 for Wastewater Surveillance
This study showed significant higher BCoV recovery and SARS-CoV-2 viral RNA in wastewater solid fraction (p=0.006) than liquid fraction. Our result suggests that the solid fraction of wastewater samples is more suitable for recovering enveloped viruses from wastewater, and the DC and AHAP methods equally provide suitably rapid, cost-effective, and significantly higher recovery of SARS-CoV-2 viral RNA in wastewater samples.PMID:37558056 | DOI:10.1016/j.jviromet.2023.114790
Source: Journal of Virological Methods - August 9, 2023 Category: Virology Authors: Doris Yoong Wen Di Bo Li Min Ki Jeon Tao Yan Source Type: research
Inhibitory effect of lactoferrin-coated zinc nanoparticles on SARS-CoV-2 replication and entry along with improvement of lung fibrosis induced in adult male albino rats
Int J Biol Macromol. 2023 Jun 23:125552. doi: 10.1016/j.ijbiomac.2023.125552. Online ahead of print.ABSTRACTSevere acute respiratory syndrome 2019-new coronavirus (SARS-CoV-2) is a major global challenge caused by a pandemic disease, named 'COVID-19' with no effective and selective therapy available so far. COVID-19-associated mortality is directly related to the inability to suppress the viral infection and the uncontrolled inflammatory response. So, we investigated the antiviral efficiency of the nanofabricated and well-characterized lactoferrin-coated zinc nanoparticles (Lf-Zn-NPs) on SARS-CoV-2 replication and entry in...
Source: International Journal of Biological Macromolecules - June 25, 2023 Category: Biochemistry Authors: Esmail M El-Fakharany Hamada El-Gendi Yousra A El-Maradny Marwa M Abu-Serie Khaled G Abdel-Wahhab Marwa E Shaban Mahmoud Ashry Source Type: research
Circulating ACE2 level and zinc/albumin ratio as potential biomarkers for a precision medicine approach to COVID-19
Adv Biol Regul. 2023 May 23;89:100973. doi: 10.1016/j.jbior.2023.100973. Online ahead of print.ABSTRACTHighly mutable influenza is successfully countered based on individual susceptibility and similar precision-like medicine approach should be effective against SARS-COV-2. Among predictive markers to bring precision medicine to COVID-19, circulating ACE2 has potential features being upregulated in both severe COVID-19 and predisposing comorbidities. Spike SARS-CoVs were shown to induce ADAM17-mediated shedding of enzymatic active ACE2, thus accounting for its increased activity that has also been suggested to induce positi...
Source: Adv Data - May 31, 2023 Category: Epidemiology Authors: Serena Benedetti Davide Sisti Daniela Vandini Simone Barocci Maurizio Sudano Eugenio Carlotti Jade Lee Lee Teng Loris Zamai Source Type: research
Utilization of Marine Seaweeds as a Promising Defense Against COVID-19: a Mini-review
Mar Biotechnol (NY). 2023 May 27. doi: 10.1007/s10126-023-10214-7. Online ahead of print.ABSTRACTCOVID-19 is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which mainly affects the respiratory system. It has been declared as a "pandemic" in March 2020 by the World Health Organization due to the high spreading rate. SARS-CoV-2 binds with the angiotensin-converting enzyme 2 (ACE2) receptors on the cell surface which leads to the downregulation of ACE2 and upregulation of angiotensin-converting enzyme (ACE) receptors. The elevated level of cytokines and ACE receptors leads to the ...
Source: Marine Biotechnology - May 27, 2023 Category: Biotechnology Authors: M D T L Gunathilaka Source Type: research
Indian food habit & amp; food ingredients may have a role in lowering the severity & amp; high death rate from COVID-19 in Indians: findings from the first nutrigenomic analysis
CONCLUSIONS: Our results suggest that Indian food components suppress cytokine storm and various other severity-related pathways of COVID-19 and may have a role in lowering severity and death rates from COVID-19 in India as compared to western populations. However, large multi-centered case-control studies are required to support our current findings.PMID:37102510 | DOI:10.4103/ijmr.ijmr_1701_22
Source: Indian J Med Res - April 27, 2023 Category: Research Authors: Debmalya Barh Fl ávia Figueira Aburjaile Thais Silva Tavares Miguel Etcheverria da Silva Gabriel Pissolati Mattos Bretz Igor Fernando Martins Rocha Annesha Dey Renan Pedra de Souza Arist óteles Góes-Neto S érvio Pontes Ribeiro Khalid J Alzahrani Ahmad Source Type: research
