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Effects of Statins on Early and Late Clinical Outcomes of Carotid Endarterectomy and the Rate of Post-Carotid Endarterectomy Restenosis
Statins have no effect on post-carotid endarterectomy (CEA) restenosis but are associated with decreased death rates in patients with diabetes trending to lower both death and stroke rates in diabetic patients with hypercholesterolemia.
Source: Journal of Vascular Surgery - November 22, 2015 Category: Surgery Authors: A.F. AbuRahma, M. Srivastava, P.A. Stone Tags: Abstract Source Type: research

Simultaneous coronary and carotid revascularisation
Conclusion According to our experiences and results, the simultaneous performance of CEA and CABG in patients with severe coexisting carotid artery disease who require coronary revascularization has proved to be a safe and efficacious operative strategy in these high-risk patients.
Source: Cor et Vasa - February 23, 2016 Category: Cardiology Source Type: research

Outcomes of 1000 Carotid Wallstent Implantations: Single-Center Experience
Conclusion: CAS is a valid method for treating carotid artery disease, with very low rates of major adverse events and neurologic complications. The Carotid Wallstent seems to have excellent results, even with complex plaque morphology, and a low incidence of restenosis at follow-up.
Source: Journal of Endovascular Therapy - March 16, 2016 Category: Surgery Authors: Ronchey, S., Praquin, B., Orrico, M., Serrao, E., Ciceroni, C., Alberti, V., Fazzini, S., Mangialardi, N. Tags: Carotid Artery Stenting Source Type: research

High-grade carotid artery stenosis: A forgotten area in cardiovascular risk management
Conclusions The clinical event rate was high in patients with high-grade CAS and the management of cardiovascular risk was deficient in all aspects.
Source: European Journal of Preventive Cardiology - August 10, 2016 Category: Cardiology Authors: Good, E., Länne, T., Wilhelm, E., Perk, J., Jaarsma, T., de Muinck, E. Tags: Original scientific papers Source Type: research

Diabetes Mellitus with Chronic Complications in Relation to Carotid Endarterectomy and Carotid Artery Stenting Outcomes
Carotid endarterectomy and carotid artery stenting are effective treatment procedures for carotid artery stenosis. Although diabetes mellitus is highly prevalent among patients undergoing these revascularization procedures, few studies have examined their impact on periprocedural outcomes.
Source: Journal of Stroke and Cerebrovascular Diseases - October 30, 2016 Category: Neurology Authors: Oluwole Adegbala, Kimberly D. Martin, David Otuada, Tomi Akinyemiju Source Type: research

Carotid Endarterectomy in Octogenarians and Nonagenarians: Is it Worth the Effort ?
CONCLUSIONS: Carotid endarterectomy can be performed in the elderly as safely and cost effectively as in the younger population. PMID: 27819579 [PubMed - in process]
Source: Acta Chirurgica Belgica - November 9, 2016 Category: Surgery Tags: Acta Chir Belg Source Type: research

Comparison of Early Outcomes and Restenosis Rate Between Carotid Endarterectomy and Carotid Artery Stenting Using Propensity Score Matching Analysis.
CONCLUSION: This PSM based observation reconfirmed previous trial results in both asymptomatic and symptomatic patients with carotid artery stenosis in routine clinical practice: CEA showed lower 30 day MACE and mid-term restenosis rates than CAS. PMID: 28893482 [PubMed - as supplied by publisher]
Source: PubMed: Eur J Vasc Endovasc ... - September 8, 2017 Category: Surgery Authors: Heo SH, Yoon KW, Woo SY, Park YJ, Kim YW, Kim KH, Chung CS, Bang OY, Kim DI Tags: Eur J Vasc Endovasc Surg Source Type: research

Diabetes adversely affects phospholipid profiles in human carotid artery endarterectomy plaques Patient-Oriented and Epidemiological Research
Patients with diabetes are at higher risk of developing carotid artery stenosis and resultant stroke. Arachidonoyl phospholipids affect plaque inflammation and vulnerability, but whether diabetic patients have unique carotid artery phospholipidomic profiles is unknown. We performed a comprehensive paired analysis of phospholipids in extracranial carotid endarterectomy (CEA) plaques of matched diabetic and nondiabetic patients and analyzed mass spectrometry-derived profiles of three phospholipids, plasmenyl-phosphatidylethanolamine (pPE), phosphatidylserine (PS), and phosphatidylinositol (PI), in maximally (MAX) and minimal...
Source: The Journal of Lipid Research - April 1, 2018 Category: Lipidology Authors: Zayed, M. A., Hsu, F.-F., Patterson, B. W., Yan, Y., Naim, U., Darwesh, M., De Silva, G., Yang, C., Semenkovich, C. F. Tags: Patient-Oriented and Epidemiological Research Source Type: research

Glucose screening in pregnancy and future risk of cardiovascular disease in women: a retrospective, population-based cohort study
Publication date: Available online 27 March 2019Source: The Lancet Diabetes & EndocrinologyAuthor(s): Ravi Retnakaran, Baiju R ShahSummaryBackgroundIn studies to date, gestational diabetes has consistently been associated with an increased future risk of cardiovascular disease, irrespective of the antepartum screening protocol or diagnostic criteria by which gestational diabetes is diagnosed. We reasoned that the resultant heterogeneity in the severity of dysglycaemia in women with gestational diabetes suggests that the relationship between gestational glycaemia and subsequent cardiovascular disease probably extends into t...
Source: The Lancet Diabetes and Endocrinology - March 28, 2019 Category: Endocrinology Source Type: research

Prognostic factors of long-term survival to guide selection of asymptomatic patients for carotid endarterectomy.
CONCLUSIONS: The presence of one or more prognostic factors as well as the various risk prediction models can guide selection of ACS patient subgroups for which a prophylactic CEA should or should not be offered. Decisions to offer prophylactic CEA should weigh in factors like surgeon's experience and hospital expertise/volume. Asymptomatic patients not expected to live long enough to benefit from the procedure should not be considered for CEA, but should be offered best medical treatment. PMID: 31814375 [PubMed - as supplied by publisher]
Source: International Angiology - December 11, 2019 Category: Cardiology Tags: Int Angiol Source Type: research

Predictors of outcome events and 6-year mortality after carotid endarterectomy and carotid stenting in patients with carotid artery stenosis.
CONCLUSIONS: The results of our study show that long-term mortality does not differ between CEA and CAS. PMID: 33242214 [PubMed - as supplied by publisher]
Source: Neurologia i Neurochirurgia Polska - November 26, 2020 Category: Neurology Authors: Leško N, Maretta M, Škorvánek M, Frankovičová M, Sihotský V, Špak Ľ, Gdovinová Z Tags: Neurol Neurochir Pol Source Type: research

Severe contralateral carotid stenosis or occlusion drive 30-day risk after carotid endarterectomy.
CONCLUSIONS: SCSO is an independent predictor of 30-day major adverse events. Whether these patients with SCSO are suitable for carotid endarterectomy should be carefully considered. PMID: 33596788 [PubMed - as supplied by publisher]
Source: Vascular - February 17, 2021 Category: Surgery Authors: Zhao W, Gao F, Wu C, Peng D, Jin X, Lou L, Sun W Tags: Vascular Source Type: research

Severe contralateral carotid stenosis or occlusion drive 30-day risk after carotid endarterectomy
CONCLUSIONS: SCSO is an independent predictor of 30-day major adverse events. Whether these patients with SCSO are suitable for carotid endarterectomy should be carefully considered.PMID:33596788 | DOI:10.1177/1708538121993619
Source: Vascular - February 18, 2021 Category: Surgery Authors: Wenyan Zhao Faliang Gao Cheng Wu Deqing Peng Xiao Jin Lin Lou Weijun Sun Source Type: research

Revised cardiac score index is a predictor of long-term outcomes after carotid endarterectomy
Conclusion: RCRI and CtRCRI did not predict MACE in the perioperative period but are good predictors of 30-day complications (Clavien-Dindo ≥2). Both RCRI and CtRCRI have good prognostic value as predictors of long-term cardiovascular events.PMID:35171024 | DOI:10.1024/0301-1526/a000988
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - February 16, 2022 Category: Surgery Authors: Filipa J ácome Leandro N óbrega Ant ónio Pereira-Neves Lu ís Duarte-Gamas Joana Mour ão Pedro Videira-Reis Marina Dias-Neto Jo ão Rocha-Neves Source Type: research

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