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Condition: Diabetes
Procedure: Coronary Artery Bypass Graft

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Total 437 results found since Jan 2013.

High Thoracic Epidural Analgesia as an Adjunct to General Anesthesia is Associated With Better Outcome in Low-to-Moderate Risk Cardiac Surgery Patients
Conclusion: This large, uniquely matched single-center cohort was generated, and, subject to the listed limitations the authors concluded that supplemental HTEA to general anesthesia had a better outcome in low-risk cardiac surgery patients, with a significantly lower 6-month mortality rate compared with the control group. However, regression analysis revealed that HTEA only had an independently positive effect on the frequency of postoperative dialysis.
Source: Journal of Cardiothoracic and Vascular Anesthesia - July 31, 2013 Category: Anesthesiology Authors: Michael Stenger, Anja Fabrin, Henrik Schmidt, Jacob Greisen, Poul Erik Mortensen, Carl-Johan Jakobsen Tags: Original Article Source Type: research

The early diastolic myocardial velocity: a marker of increased risk in patients with coronary heart disease
ConclusionEm appears to be a sensitive echocardiographic index in identifying non‐diabetic patients with AMI at risk of new cardiovascular events.
Source: Clinical Physiology and Functional Imaging - December 3, 2013 Category: Radiology Authors: Jonas Johnson, Aristomenis Manouras, Fredrik Bergholm, Lars Åke Brodin, Stefan Agewall, Loghman Henareh Tags: Original Article Source Type: research

Study may bust myth of 'fat and fit' healthy obesity
Conclusion This meta-analysis provides further evidence about the known risk factors for cardiovascular disease and mortality. What this study adds is the indication that people who are metabolically unhealthy regardless of their weight are at increased risk. However, interestingly, no increase in risk was seen for the category of people who are metabolically healthy though overweight. A strength of this meta-analysis is the large sample size. However, the results should be interpreted with caution as: The studies did not use the same criteria for assessing metabolic status. The studies did not use the same criteri...
Source: NHS News Feed - December 4, 2013 Category: Consumer Health News Tags: Food/diet Lifestyle/exercise Obesity Source Type: news

CABG versus PCI in diabetic patients with multivessel disease after risk stratification by the SYNTAX score: A pooled analysis of the SYNTAX and FREEDOM trials
The 2010 European guidelines for myocardial revascularization indicate coronary artery bypass grafting (CABG) as a class I recommendation for patients with stable coronary multivessel disease (MVD), regardless of the angiographic burden reflected by the SYNTAX score . In contrast, percutaneous coronary intervention (PCI) is contraindicated (class III) in patients with MVD and intermediate to high (>22) SYNTAX score, while it is considered reasonable (class IIa) in patients with MVD and low (0–22) SYNTAX score. Recently, in the 2013 European guidelines on the management of patients with diabetes mellitus, PCI for MVD has ...
Source: International Journal of Cardiology - April 3, 2014 Category: Cardiology Authors: Davide Capodanno, Piera Capranzano, Corrado Tamburino Tags: Letters to the Editor Source Type: research

Comparison of bypass surgery and drug-eluting stenting in diabetic patients with left main and/or multivessel disease: A systematic review and meta-analysis of randomized and nonrandomized studies.
CONCLUSIONS: CABG for patients with diabetes mellitus and LM and/or MVD had advantages over PCI-DES in all-cause death, nonfatal MI, and repeat revascularization, but the substantial disadvantage in nonfatal stroke. The high-selected patients (RCTs) risked a higher mortality than the real-world patients (OCTs). PMID: 24846507 [PubMed - as supplied by publisher]
Source: Cardiology Journal - May 20, 2014 Category: Cardiology Authors: Huang F, Lai W, Chan C, Peng H, Zhang F, Zhou Y, Teng S, Huang Z Tags: Cardiol J Source Type: research

Coronary artery bypass grafting versus drug‐eluting stents in patients with severe coronary artery disease and diabetes mellitus: a systematic review and meta‐analysis
ConclusionsFor patients with diabetes mellitus and severe coronary artery disease, CABG was superior to DES in that it significantly improve overall and MACCE‐free survival rate and reduce incidences of myocardial infarction and repeat revascularization in the long‐term follow‐up, although it was associated with more perioperative risks and a higher incidence of stroke. Therefore, CABG should remain the gold standard for these patients.
Source: Journal of Diabetes - June 3, 2014 Category: Endocrinology Authors: Yi‐cheng Wu, Ting‐wei Su, Jian‐feng Zhang, Wei‐feng Shen, Guang Ning, Ye Kong Tags: Original Article Source Type: research

Clinical and Economic Burden in Patients with Diagnosis of Peripheral Arterial Disease in a Claims Database in Japan.
Abstract PURPOSE: The effect of peripheral arterial disease (PAD) among young and middle-aged adults can be significant, but no previous study has examined the prognosis and the associated health care cost of the disease in this population. We evaluated the clinical and economic burden of PAD in patients from a large claims database to clarify the effect of the disease on a relatively young working Japanese population. METHODS: Patients aged ≥45 and ≤64 years with first PAD diagnosis between 2005 and 2011 comprised the PAD cohort (n = 362); an age- and sex-matched non-PAD comparison cohort (n = 362) was a...
Source: Clinical Therapeutics - July 7, 2014 Category: Drugs & Pharmacology Authors: Hosaka A, Miyata T, Onishi Y, Liao L, Zhang Q Tags: Clin Ther Source Type: research

Clinical outcomes of hybrid coronary revascularization versus coronary artery bypass surgery in patients with diabetes mellitus
Background: Hybrid coronary revascularization (HCR) involves minimally invasive left internal mammary artery to left anterior descending coronary artery grafting combined with percutaneous coronary intervention (PCI) of non–left anterior descending vessels. The safety and efficacy of HCR among diabetic patients are unknown.Methods: Patients with diabetes were included who underwent HCR at a US academic center between October 2003 and September 2013. These patients were matched 1:5 to similar patients treated with coronary artery bypass grafting (CABG) using a propensity score (PS)-matching algorithm. Conditional logistic...
Source: American Heart Journal - July 14, 2014 Category: Cardiology Authors: Ralf E. Harskamp, Patrick F. Walker, John H. Alexander, Ying Xian, Henry A. Liberman, Robbert J. de Winter, Thomas A. Vassiliades, Eric D. Peterson, John D. Puskas, Michael E. Halkos Tags: Diabetes and Metabolism Source Type: research

Prevalence and impact of carotid disease in adult Saudi patients undergoing isolated coronary artery bypass surgery on early postoperative outcome
The aim of the study is to assess the prevalence of carotid disease in our Saudi population undergoing coronary artery bypass surgery and to determine its impact on stroke and early postoperative outcome. A total of 3197 consecutive adult patients underwent major cardiac surgery in our center between January 2002 and December 2012. Of these, 3150 had preoperative duplex scanning, and out of these, 210 patients (6.6%) had significant carotid artery disease defined as ≥75% stenosis (Group A), whereas 2940 (94.4%) were free from carotid artery disease (Group B). Both groups were compared for the presence of preoperative ri...
Source: European Journal of Heart Failure Supplements - November 10, 2014 Category: Cardiology Authors: Arifi, A. A., Ahmad, M., Van Onselen, R., Najm, H. K. Tags: Articles Source Type: research

Coronary Revascularization in Diabetic Patients: A Systematic Review and Bayesian Network Meta-analysis.
CONCLUSION: Coronary artery bypass grafting seems to be the preferred revascularization technique in diabetics, especially if long-term survival is anticipated. However, because of residual uncertainties and increased risk for stroke with CABG, clinical judgment is required when choosing a revascularization technique in patients with diabetes. PRIMARY FUNDING SOURCE: Fonds de recherche du Québec-Santé. PMID: 25402514 [PubMed - in process]
Source: Annals of Internal Medicine - November 18, 2014 Category: Internal Medicine Authors: Tu B, Rich B, Labos C, Brophy JM Tags: Ann Intern Med Source Type: research

Comparison of the incidence of postoperative neurologic complications after on-pump versus off-pump coronary artery bypass grafting in high-risk patients: A meta-analysis of 11 studies
Neurological complications, such as stroke and transient ischemic attack, are major adverse cardiac events (MACE) following coronary artery bypass grafting (CABG) and markedly reduce patient short-term and long-term survival [1]. Farkouh et al. found that the 5-year rate of stroke was significantly higher after CABG than after percutaneous coronary intervention in patients with diabetes and multivessel coronary artery disease [2]. Thus, strategies to reduce neurological complications after CABG can improve patient outcomes.
Source: International Journal of Cardiology - March 11, 2015 Category: Cardiology Authors: Jiayang Wang, Chengxiong Gu, Mingxin Gao, Wenyuan Yu, Haitao Li, Fan Zhang, Yang Yu Tags: Letters to the Editor Source Type: research

Surgical Versus Percutaneous Coronary Revascularization for Multivessel Disease in Diabetic Patients With Non-ST-Segment-Elevation Acute Coronary Syndrome: Analysis From the Acute Catheterization and Early Intervention Triage Strategy Trial Coronary Artery Disease
Conclusions— In the large-scale ACUITY trial, diabetic patients with acute coronary syndrome and multivessel disease treated with PCI rather than CABG had less bleeding and acute kidney injury, greater need for repeat revascularization procedures, and comparable rates of myocardial infarction, stroke, and death through 1-year follow-up. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00093158.
Source: Circulation: Cardiovascular Interventions - May 27, 2015 Category: Cardiology Authors: Ben-Gal, Y., Mohr, R., Feit, F., Ohman, E. M., Kirtane, A., Xu, K., Mehran, R., Stone, G. W. Tags: Other diabetes, Catheter-based coronary interventions: stents, CV surgery: coronary artery disease Source Type: research

Impact of prasugrel pretreatment and timing of coronary artery bypass grafting on clinical outcomes of patients with non-ST-segment elevation myocardial infarction: from the ACCOAST study
Conclusions In ACCOAST, early (<2.98 days) surgical revascularization carried increased risk of bleeding and ischemic complications without affecting all-cause mortality through 30 days. Baseline troponin and prasugrel pretreatment did not impact ischemic clinical outcomes.
Source: American Heart Journal - July 30, 2015 Category: Cardiology Source Type: research

Midterm Outcome of Coronary Artery Bypass Grafting in Young Patients: A Multicenter Italian Study
Conclusions Patients less than 50 years of age undergoing CABG have an excellent outcome compared with elderly patients. These data indicate that despite its premature onset, coronary artery disease in young patients does not have a more aggressive course than that in older patients.
Source: The Annals of Thoracic Surgery - August 11, 2015 Category: Cardiovascular & Thoracic Surgery Source Type: research

Midterm Outcome of Coronary Artery Bypass Grafting in Young Patients: A Multicenter Italian Study.
CONCLUSIONS: Patients less than 50 years of age undergoing CABG have an excellent outcome compared with elderly patients. These data indicate that despite its premature onset, coronary artery disease in young patients does not have a more aggressive course than that in older patients. PMID: 26271584 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - August 11, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Rosato S, Biancari F, D'Errigo P, Fusco D, Seccareccia F Tags: Ann Thorac Surg Source Type: research