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Coronary Calcium Score for the Prediction of Asymptomatic Coronary Artery Disease in Patients With Ischemic Stroke
Conclusion: The necessity for CAC evaluation could be determined based on the presence of risk factors and significant stenosis of the cervicocephalic arteries. CAC evaluation may be useful for screening for severe CAD in stroke patients.
Source: Frontiers in Neurology - March 26, 2020 Category: Neurology Source Type: research

Plaque Composition in the Proximal Superficial Femoral Artery and Peripheral Artery Disease Events
Conclusions Among patients with PAD, LRNC in the SFA was associated with higher rates of clinical PAD events, and this association was independent of ABI. Further study is needed to determine whether interventions that reduce SFA LRNC prevent PAD events.
Source: Journal of the American College of Cardiology: Cardiovascular Imaging - September 4, 2017 Category: Radiology Authors: McDermott, M. M., Kramer, C. M., Tian, L., Carr, J., Guralnik, J. M., Polonsky, T., Carroll, T., Kibbe, M., Criqui, M. H., Ferrucci, L., Zhao, L., Hippe, D. S., Wilkins, J., Xu, D., Liao, Y., McCarthy, W., Yuan, C. Tags: Original Research Source Type: research

High androgens in postmenopausal women and the risk for atherosclerosis and cardiovascular disease: the Rotterdam Study.
Conclusion: Postmenopausal high androgen levels were not associated with an increased risk for CVD. Cardiovascular health in women with PCOS might be better than was anticipated. PMID: 29408955 [PubMed - as supplied by publisher]
Source: The Journal of Clinical Endocrinology and Metabolism - February 1, 2018 Category: Endocrinology Authors: Meun C, Franco OH, Dhana K, Jaspers L, Muka T, Louwers Y, Ikram MA, Fauser BCJM, Kavousi M, Laven JSE Tags: J Clin Endocrinol Metab Source Type: research

Calcium intake, calcium supplementation and cardiovascular disease and mortality in the British population: EPIC-norfolk prospective cohort study and meta-analysis
AbstractThe role of dietary calcium in cardiovascular disease prevention is unclear. We aimed to determine the association between calcium intake and incident cardiovascular disease and mortality. Data were extracted from the European Prospective Investigation of Cancer, Norfolk (EPIC-Norfolk). Multivariable Cox regressions analysed associations between calcium intake (dietary and supplemental) and cardiovascular disease (myocardial infarction, stroke, heart failure, aortic stenosis, peripheral vascular disease) and mortality (cardiovascular and all-cause). The results of this study were pooled with those from published pr...
Source: European Journal of Epidemiology - December 31, 2020 Category: Epidemiology Source Type: research

Risk of Cardiovascular Conditions in Patients with Chronic Hypoparathyroidism: A Retrospective Cohort Study
ConclusionsThis large retrospective cohort study showed that chronic hypoparathyroidism was associated with increased risk of incident cardiovascular conditions and arrhythmias. Results should be evaluated in light of limitations inherent to claims database analyses. Further studies are warranted to investigate reasons for these risks and to develop strategies for reducing cardiovascular conditions in patients with chronic hypoparathyroidism.
Source: Advances in Therapy - June 24, 2021 Category: Drugs & Pharmacology Source Type: research

Does Mitral Valve Calcium In Patients Undergoing Mitral Valve Replacement Portend Worse Survival?
ConclusionsConservative approach to treat MAC achieves satisfactory results. Patients with MAC have significant comorbidities contributing to a worse survival though MAC in itself is not a risk factor for mortality.
Source: The Annals of Thoracic Surgery - November 3, 2018 Category: Cardiovascular & Thoracic Surgery Source Type: research

Coronary artery calcifications and 6-month mortality in patients with COVID-19 without known atheromatous disease
CONCLUSIONS: Non-electrocardiogram-gated computed tomography during the initial pulmonary assessment of patients with COVID-19 without atherosclerotic cardiovascular disease showed a high prevalence of mild, moderate and heavy CAC. CAC score was related to 6-month mortality, independent of conventional cardiovascular risk factors. These results highlight the importance of CAC scoring for patients hospitalized with COVID-19, and calls for attention to patients with high CAC.PMID:35305915 | DOI:10.1016/j.acvd.2022.02.007
Source: Archives of Cardiovascular Diseases - March 20, 2022 Category: Cardiology Authors: Anne-Sophie Le Hir Antoine Fayol Elie Mousseaux Nicolas Danchin Victoria Tea Chekrallah Chamandi Gilles Soulat Etienne Puymirat Source Type: research

Mendelian randomization study of the effect of coronary artery calcification on atherosclerotic cardiovascular diseases
In this study, we used Mendelian randomization (MR) to systematically investigate the causal role of CAC across a broad range of atherosclerotic cardiovascular diseases including coronary heart disease, angina, MI, ischemic heart disease, stroke, and peripheral vascular disease. Publicly available data from the UK biobank and other data sources were used. Using the two-sample Mendelian randomization (MR) approach, we applied 3 MR models including the inverse variance weighted, the weighted-median, and the weighted-mode methods. Eight SNPs associated with CAC were selected as instrumental variables. We observed causal evide...
Source: Atherosclerosis - September 1, 2022 Category: Cardiology Authors: Wichanon Sae-Jie Tarinee Tangcharoen Prin Vathesatogkit Wichai Aekplakorn Pimphen Charoen Source Type: research