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Associations between chronic conditions and death in hospital among adults (aged 20+ years) during first acute care hospitalizations with a confirmed or suspected COVID-19 diagnosis in Canada
ConclusionConditions most strongly associated with in-hospital death among hospitalized adults with COVID-19 vary across the life course, and the impact of chronic conditions and comorbidity attenuate with age.
Source: PLoS One - January 4, 2023 Category: Biomedical Science Authors: Dianne Zakaria Source Type: research

Association of body mass index with COVID-19-related neurologic sequelae: a retrospective cohort study
This study demonstrates the absence of an association between BMI and neurologic manifestations following acute COVID-19 illness. Prospective studies using standardized data collection tools and direct measures of body fat are warranted to obtain more valid effect estimates.
Source: Clinical and Experimental Medicine - December 16, 2022 Category: Research Source Type: research

COPD and COVID-19: a dangerous association?
Conclusion: COPDs patients are mostly ederly men with comorbidities. The most effective treatment for them was stabilization of comorbidities and conventional oxygen and for the most severe Helmet-CPAP and NIV. In addition, COPD patients had no higher risk of mortality from COVID-19 than individuals without a pre-existing diagnosis of COPD.
Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Mendez Gonzalez, L., Ferreira, J., Caneiras, C. Tags: 05.02 - Monitoring airway disease Source Type: research

Effects of statins on outcomes in Hispanic patients with COVID-19
The Hispanic population is regarded among those who are at greater risk of adverse prognoses due to higher rates of diabetes and obesity in the USA during the COVID-19 pandemic. Statin medications are speculated to help treat the infection by decreasing inflammation caused by COVID-19. In this retrospective, observational study, outcomes of statin use were assessed among Hispanic patients with COVID-19 by screening all patients hospitalized between March, 2020 and March, 2021 at a tertiary care hospital in El Paso, Texas, resulting in a total of 1039 patients. The patients were categorized into a group of either being on s...
Source: Journal of Investigative Medicine - December 1, 2022 Category: Research Authors: Khalafi, S., Evans, J., Lumbreras, T., Tiula, K., Helmsdoerfer, K., Dwivedi, A. K., Dihowm, F. Tags: COVID-19 Original research Source Type: research

Neurological Complications and Consequences of the Novel Coronavirus COVID-19 Infection in Elderly and Senile Patients (Literature Review)
AbstractBased on available publications, the article systematizes information about some forms of lesions of the central nervous system (CNS), their pathogenesis and clinical manifestations in the case of COVID-19. The risk factors, mechanisms of development, diagnostic approach, and the age characteristics of patients with neurological complications of COVID-19 are discussed. The specific mechanisms of the neuroinvasiveness and neurovirulence of the SARS-CoV-2 virus, regardless of the age of patients and the presence of risk factors, lead to systemic damage to the endothelium of small-caliber vessels, generalized thrombov...
Source: Advances in Gerontology - December 1, 2022 Category: Geriatrics Source Type: research

Prognostic factors for mortality, intensive care unit and hospital admission due to SARS-CoV-2: a systematic review and meta-analysis of cohort studies in Europe
Eur Respir Rev. 2022 Nov 2;31(166):220098. doi: 10.1183/16000617.0098-2022. Print 2022 Dec 31.ABSTRACTBACKGROUND: As mortality from coronavirus disease 2019 (COVID-19) is strongly age-dependent, we aimed to identify population subgroups at an elevated risk for adverse outcomes from COVID-19 using age-/gender-adjusted data from European cohort studies with the aim to identify populations that could potentially benefit from booster vaccinations.METHODS: We performed a systematic literature review and meta-analysis to investigate the role of underlying medical conditions as prognostic factors for adverse outcomes due to sever...
Source: Respiratory Care - November 2, 2022 Category: Respiratory Medicine Authors: Constantine I Vardavas Alexander G Mathioudakis Katerina Nikitara Kimon Stamatelopoulos Georgios Georgiopoulos Revati Phalkey Jo Leonardi-Bee Esteve Fernandez Dolors Carnicer-Pont J ørgen Vestbo Jan C Semenza Charlotte Deogan Jonathan E Suk Piotr Kramarz Source Type: research

The impact of first wave of the SARS-CoV-2 2019 pandemic in Poland on characteristics and outcomes of patients hospitalized due to stable coronary artery disease
CONCLUSIONS: The SARS-CoV-2 2019 pandemic affected the characteristics and hospitalization course of stable angina patients hospitalized following the first wave. The hospitalization outcome was similar in the analyzed time intervals. The higher prevalence of comorbidities raises concern regarding upcoming years.PMID:36200545 | DOI:10.5603/CJ.a2022.0094
Source: Cardiology Journal - October 6, 2022 Category: Cardiology Authors: Justyna Jankowska-Sanetra Krzysztof Sanetra Marta Konopko Monika Kutowicz Magdalena Synak Krzysztof Milewski Pawe ł Kaźmierczak Łukasz Kołtowski Piotr P Buszman Source Type: research

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