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Fight Aging! Newsletter, September 18th 2023
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - September 17, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, August 14th 2023
This study demonstrates just how vital the thymus is to maintaining adult health." « Back to Top Does Amyloid-β Aggregation Cause Broad Disruption of Proteostasis? https://www.fightaging.org/archives/2023/08/does-amyloid-%ce%b2-aggregation-cause-broad-disruption-of-proteostasis/ Researchers here speculate on the ability of insoluble amyloid-β aggregates to be broadly disruptive of the solubility of many other proteins, and thus disruptive to cell and tissue function. Is this important in aging? The evidence here shows the existence of the mechanism in a lower species, but that doesn't n...
Source: Fight Aging! - August 13, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Investigating gender differences in the Co-occurrence of PTSD and food addiction
DISCUSSION: Food addiction, but not obesity, appears to co-occur with PTSD more strongly than other types of problematic substance use (alcohol, cannabis, cigarettes, nicotine vaping). This risk appears to be particularly high for men compared to women. Assessing for food addiction in those with PTSD, particularly in men, may assist in identifying high-risk groups.PMID:37236363 | DOI:10.1016/j.appet.2023.106605
Source: Appetite - May 26, 2023 Category: Nutrition Authors: Lindzey V Hoover Hayley P Yu Elizabeth R Duval Ashley N Gearhardt Source Type: research

Acute effects of exercise among individuals with schizophrenia who smoke cigarettes
Addict Behav. 2023 May 5;144:107749. doi: 10.1016/j.addbeh.2023.107749. Online ahead of print.ABSTRACTPeople with schizophrenia (SCZ) have a shorter life expectancy than those without psychiatric conditions. Of note, people with SCZ have high rates of cigarette smoking, physical inactivity, and obesity. These factors all coalesce to contribute to compromised health in this population, with smoking as a primary contributor. Therefore, it is paramount to develop effective smoking cessation strategies for this population. The purpose of this study was to investigate whether walking at a brisk pace, relative to engaging in pas...
Source: Addictive Behaviors - May 12, 2023 Category: Addiction Authors: Cara M Murphy Michael C Onu Christine Goodwin David M Williams Jennifer W Tidey Source Type: research

Lorcaserin: worthy of further insights? Results from recent research
CNS Neurol Disord Drug Targets. 2023 Mar 30. doi: 10.2174/1871527322666230330124137. Online ahead of print.ABSTRACTLorcaserin is a 3-benzazepine that binds 5-HT2C serotonin receptors in the hypothalamus, where it mediates lack of hunger and/or satiety, and in the ventral tegmental area, the site of origin of the mesolimbic and mesocortical dopaminergic projections, which mediate pleasure and reward. The drug has been first developed for the treatment of obesity, where it has shown efficacy, and subsequently trialed to counter substance use (mostly cocaine, cannabis, opioids, and nicotine) and craving, but showed inconsiste...
Source: CNS and Neurological Disorders Drug Targets - April 3, 2023 Category: Drugs & Pharmacology Authors: Marianna Mazza Georgios Demetrios Kotzalidis Giuseppe Marano Domenico De Berardis Giovanni Martinotti Enrico Romagnoli Giuseppe Biondi-Zoccai Antonio Abbate Gabriele Sani Source Type: research

Absence of Association of Tinnitus With Pre-existing Hypertension: A Population-based Study
CONCLUSIONS: Our population-based study found no evidence for an association between tinnitus and pre-existing hypertension.PMID:35923124 | DOI:10.1177/00034894221115756
Source: The Annals of Otology, Rhinology, and Laryngology - August 4, 2022 Category: ENT & OMF Authors: Po-Hsiu Huang Sudha Xirasagar Jin-Hua Chen Yen-Fu Cheng Nai-Wen Kuo Herng-Ching Lin Source Type: research

Associations between eating disorder symptoms and smoking and vaping use and motives in college students
In this study, 716 college students (M age = 19.23, SD = 1.65; 61 % female) completed an online survey that included the Eating Pathology Symptoms Inventory, smoking and vaping questionnaires, and the Drinking Motives Questionnaire-Revised, which was modified for smoking and vaping. We examined mean differences in ED symptoms in lifetime (and past-month) cigarette and e-cigarette users versus non-users, and investigated correlations between ED symptoms and smoking and vaping motives. Finally, we evaluated whether biological sex influenced the results. Overall, 30.4 % of students reported lifetime smoking, 10.5 % reported p...
Source: Eating Behaviors - July 15, 2022 Category: Eating Disorders & Weight Management Authors: Kathrin M Hennigan Kathleen R Olson Jessica H Baker Melissa A Munn-Chernoff Source Type: research