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Total 139 results found since Jan 2013.

A Case of Transient Global Amnesia: A Review and How It May Shed Further Insight into the Neurobiology of Delusions
Conclusion In closing, our patient’s episode of TGA combined with her emotional and perceptual response lends credence to the proposal of a “fear/paranoia” circuit in the genesis of paranoid delusions—a circuit incorporating amygdala, frontal, and parietal cortices. Here, neutral or irrelevant stimuli, thoughts, and percepts come to engender fear and anxiety, while dysfunction in frontoparietal circuitry engenders inappropriate social predictions and maladaptive inferences about the intentions of others.[54] Hippocampus relays information about contextual information based on past experiences and the current situat...
Source: Innovations in Clinical Neuroscience - April 1, 2016 Category: Neuroscience Authors: ICN Online Editor Tags: Anxiety Disorders Behavioral and Cognitive Neurology Case Report Cognition Current Issue Dementia Medical Issues Neurologic Systems and Symptoms Psychiatry Schizophrenia delusions hippocampus neurobiology Transient global amnesia Source Type: research

A twist on the genetic link between Alzheimer’s and heart disease
Alzheimer’s disease often strikes fear in people’s hearts because it gradually erodes a person’s ability to remember, think, and learn. There is no cure, and available treatments alleviate symptoms only temporarily. An estimated 5.3 million Americans currently have Alzheimer’s disease, yet this brain disorder is far less common than heart disease. More than 85 million people in the United States are living with some form of cardiovascular disease or the after-effects of stroke, which also affects brain function. Many people don’t realize that Alzheimer’s and heart disease share a genetic link: the apolipoprotei...
Source: New Harvard Health Information - March 25, 2016 Category: Consumer Health News Authors: Julie Corliss Tags: Alzheimer's Disease Behavioral Health Brain and cognitive health Genes Healthy Aging Heart Health Memory Mental Health Source Type: news

The Biggest Medical Stories You May Have Missed In 2015
SPECIAL FROM Next Avenue By Craig Bowron As we head into the New Year, let’s take a look back and see what lessons we should have learned from medical science in 2015. The New England Journal of Medicine’s publication Journal Watch provides physicians and other health care providers with expert analysis of the most recent medical research. Below is a brief synopsis of what the Journal Watch editors felt were the most important stories in general medicine for the year 2015. While you likely heard about a couple, others probably escaped your radar. Getting Aggressive with Strokes We’re familiar with the id...
Source: Science - The Huffington Post - January 15, 2016 Category: Science Source Type: news

What does age-comparative self-rated health measure? A cross-sectional study from the Northern Sweden MONICA Project.
CONCLUSIONS: Emotions and economic satisfaction were associated with comparative self-rated health as well as some medical variables. Utilization of the knowledge of these associations in health care should be further investigated. PMID: 26644159 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Public Health - December 7, 2015 Category: Global & Universal Authors: Waller G, Janlert U, Hamberg K, Forssén A Tags: Scand J Public Health Source Type: research

Translocator protein and new targets for neuroinflammation
Abstract The mitochondrial translocator protein (18 kDa; TSPO) is involved in a wide array of physiological processes importantly including cholesterol transport, steroidogenesis and immunomodulation. In the central nervous system (CNS), TSPO expression regionally increases in glial cells upon brain insult with a differential pattern suggestive of cell-specific functions in inflammation and repair. These properties have made TSPO a valuable marker to assess the state, and progression of diverse neurological and psychiatric conditions, including traumatic brain injury, stroke, neurodegenerative diseases, anxiety, ...
Source: Clinical and Translational Imaging - November 16, 2015 Category: Radiology Source Type: research

10 Must-Do Health Checks For Women Over 50
This article first appeared on the Golden Girls Network blog. Earlier on Huff/Post50: -- This feed and its contents are the property of The Huffington Post, and use is subject to our terms. It may be used for personal consumption, but may not be distributed on a website.
Source: Healthy Living - The Huffington Post - October 31, 2015 Category: Consumer Health News Source Type: news

Radial palsy in the emergency department
Clinical introduction A 73-year-old patient with a medical history of hypertension and hypercholesterolaemia presents to the emergency department with sudden onset of weakness in the right hand and numbness in the right forearm and hand that began 5 h prior to his arrival. There was no history of trauma, he did not drink or smoke and review of systems was otherwise negative. On physical examination, there was right wrist drop with weakness of right wrist and finger extension (figure 1). Finger and wrist flexion were normal, reflexes were intact and there were no sensory alterations. The rest of the physical examinatio...
Source: Emergency Medicine Journal - October 20, 2015 Category: Emergency Medicine Authors: Camacho Velasquez, J. L., Rivero Sanz, E., Garcia Arguedas, C. Tags: Drugs: infectious diseases, EMJ Image Challenge, Stroke, Hypertension, Radiology, Clinical diagnostic tests, Radiology (diagnostics), Ethics Source Type: research

Epidemiology of stroke in Finnish patients with Huntington's disease
ConclusionCerebrovascular disease is as common in patients with HD as in the general population, but minor cerebrovascular events and vascular risk factors may remain unrecognized. Genetic burden of the HTT mutation does not appear to increase the risk of stroke.
Source: Acta Neurologica Scandinavica - September 26, 2015 Category: Neurology Authors: J. O. T. Sipilä, K. Majamaa Tags: Original Article Source Type: research

Sleep Problems May Hint At Future Heart Disease Risk
By Kathryn Doyle (Reuters Health) - Adults who get too much or too little sleep may have the beginnings of “hardening" of the arteries, which can be an early sign of heart disease, according to a new study. “Many people, up to one third or one fourth of the general population, suffer from inadequate sleep – either insufficient duration of sleep or poor quality of sleep,” said co-lead author Dr. Chan-Won Kim of Kangbuk Samsung Hospital of Sungkyunkwan University School of Medicine in Seoul, South Korea. Several studies have linked inadequate sleep with an increased risk of heart attack and stroke, bu...
Source: Healthy Living - The Huffington Post - September 10, 2015 Category: Consumer Health News Source Type: news

Carotid IMT is more associated with stroke than risk calculators
ConclusionCIMT, but neither FRS nor ORS, is independently associated with stroke among Nigerian African hypertensive patients. CIMT may be a better tool for estimating the overall risk of stroke than FRS or ORS in this population.
Source: Acta Neurologica Scandinavica - September 10, 2015 Category: Neurology Authors: M. O. Owolabi, O. M. Akpa, A. M. Agunloye Tags: Original Article Source Type: research

Exploring the nature of atheroma and cardiovascular inflammation in-vivo using Positron emission Tomography (PET).
Abstract Positron Emission Tomography (PET) has become widely established in oncology. Subsequently a whole new "toolbox" of tracers have become available to look at different aspects of cancer cell function and dysfunction including cell protein production, DNA synthesis, hypoxia and angiogenesis. In the last 5 years these tools have been used increasingly to look at the other great killer of the developed world; cardiovascular disease. For example inflammation of the unstable plaque can be imaged with fluorine-18 (F-18) fluorodeoxyglucose (FDG) and this uptake can be quantified to show the effect statins have in...
Source: The British Journal of Radiology - June 2, 2015 Category: Radiology Authors: Buscombe JR Tags: Br J Radiol Source Type: research

Special MRI scan could identify stroke risk in people with atrial fibrillation
Atrial fibrillation is a heart rhythm disorder that affects millions of people. It can make you feel lousy. Even worse, it can cause potentially disabling or deadly strokes. A special MRI scan may — I stress the “may” — help identify people with atrial fibrillation who are at high risk of having a stroke. This could help many people with this condition to avoid taking warfarin or other clot-preventing medications for life. A normal heartbeat starts in a cluster of cells called the pacemaker. It sits in the heart’s upper right chamber (the right atrium). These cells generate a pulse of electricity that...
Source: New Harvard Health Information - April 28, 2015 Category: Consumer Health News Authors: Howard LeWine, M.D. Tags: Heart Health atrial fibrillation MRI prevention special MRI scan Stroke Stroke Risk Source Type: news

Thrombus composition in acute ischemic stroke: A histopathological study of thrombus extracted by endovascular retrieval
Conclusion HAS was significantly associated with early phase thrombus composition. This may enable the prediction of thrombus composition and allow for targeted selection of therapeutic modality.
Source: Journal of Neuroradiology - April 3, 2015 Category: Radiology Source Type: research

Cardiovascular highlights from non-cardiology journals
Why is Atherosclerotic Cardiovascular Disease Risk Overestimated by the ACC/AHA Pooled Cohort Equation? The 2013 ACC/AHA Cholesterol Guidelines expand the recommendations for statin use to populations previously felt to be at lower risk. Central to risk-estimation in these guidelines is a new equation for determination of atherosclerotic cardiovascular disease (ASCVD) risk. However, this risk model has been criticized overestimating ASCVD risk in validation studies of the model. Using the Women's Health Study, Cook et al. sought to determine the reasons for risk-overestimation by the ACC/AHA model. Among 27,542 women, 632 ...
Source: Heart - February 25, 2015 Category: Cardiology Authors: Bradley, S. M. Tags: Journal scan Source Type: research

The role of the carotid doppler examination in the evaluation of atherosclerotic changes in beta thalassemia patients
Conclusion:  Carotid  Doppler is very useful method in measurement of cIMT that increased in thalassemic patients which  shows a strong relationship with features of iron overload. We recommend the routine use of Doppler measurement of cIMT in these patients to predict early atherosclerotic changes as well as in the follow-up to prevent progression of atherosclerosis. 
Source: Mediterranean Journal of Hematology and Infectious Diseases - February 16, 2015 Category: Hematology Source Type: research