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Specialty: Cardiology
Condition: Cholesterol

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Total 2240 results found since Jan 2013.

Cerebrovascular Disease and Statins
Front Cardiovasc Med. 2021 Dec 2;8:778740. doi: 10.3389/fcvm.2021.778740. eCollection 2021.ABSTRACTElevated low-density lipoprotein-cholesterol (LDL-C) is a causal factor for the development of atherosclerotic cardiovascular disease (ASCVD); accordingly, LDL-C lowering is associated with a decreased risk of progression of atherosclerotic plaques and development of complications. Currently, statins play a central role in any ASCVD management and prevention strategies, in relation to their lipid-lowering action and potentially to pleiotropic effects. After coronary artery disease, stroke is the most frequent cause of ASCVD m...
Source: Atherosclerosis - December 20, 2021 Category: Cardiology Authors: Luis M Beltr án Romero Antonio J Vallejo-Vaz Ovidio Mu ñiz Grijalvo Source Type: research

Socioeconomic factors and use of secondary preventive therapies for cardiovascular diseases in South Asia: The PURE study
Conclusion The use of secondary preventive drug therapies in patients with known CHD or stroke in South Asia is low with over 80% receiving none of the effective drug treatments. Low household wealth is the most important determinant.
Source: European Journal of Preventive Cardiology - September 11, 2015 Category: Cardiology Authors: Gupta, R., Islam, S., Mony, P., Kutty, V. R., Mohan, V., Kumar, R., Thakur, J., Shankar, V. K., Mohan, D., Vijayakumar, K., Rahman, O., Yusuf, R., Iqbal, R., Shahid, M., Mohan, I., Rangarajan, S., Teo, K. K., Yusuf, S. Tags: Original scientific papers Source Type: research

Do other cardiovascular risk factors influence the impact of age on the association between blood pressure and mortality? The MORGAM Project
Conclusion:Age-related shifts to the superiority of SBP exist for stroke mortality and all-cause mortality, and for stroke mortality was this shift influenced by other cardiovascular risk factors.
Source: Journal of Hypertension - April 7, 2014 Category: Cardiology Tags: ORIGINAL PAPERS: Cardiovascular risk Source Type: research

Adherence to Medical Therapy and the Global Burden of Cardiovascular Disease ∗
Ischemic heart disease and cerebrovascular disease account for>20% of worldwide mortality and are the 2 leading causes of death on a global basis (1). Although mortality from ischemic heart disease is greater than that from stroke worldwide, the mortality from stroke is actually higher than from ischemic heart disease in 39% of countries. For example, mortality from stroke is generally higher than that for ischemic heart disease in China, Africa, and South America. In addition, stroke disability–adjusted life-year loss rates exceed ischemic heart disease-related disability in 32% of countries (2). Because of this, strate...
Source: Journal of the American College of Cardiology - March 29, 2016 Category: Cardiology Source Type: research

Associations Between High-Density Lipoprotein Particles and Ischemic Events by Vascular Domain, Sex, and Ethnicity: A Pooled Cohort Analysis.
CONCLUSIONS: Compared with HDL-C, HDL-P was consistently associated with MI and ischemic stroke in the overall population. Differential associations of both HDL-C and HDL-P for MI by Black ethnicity suggest that atherosclerotic cardiovascular disease risk may differ by vascular domain and ethnicity. Future studies should examine individual outcomes separately. PMID: 32804568 [PubMed - in process]
Source: Circulation - August 17, 2020 Category: Cardiology Authors: Singh K, Chandra A, Sperry T, Joshi PH, Khera A, Virani SS, Ballantyne CM, Otvos JD, Dullaart RPF, Gruppen EG, Connelly MA, Ayers CR, Rohatgi A Tags: Circulation Source Type: research

Association of polygenic risk scores with incident atherosclerotic cardiovascular disease events among individuals with coronary artery calcium score of zero: The multi-ethnic study of atherosclerosis
CONCLUSIONS: Among individuals with CAC = 0, the ASCVD PRS was associated with incident ASCVD events. This appears to be driven by genetic variants related to stroke but not CHD, and particularly among women and non-Whites. ASCVD event rates remained below the threshold recommended for consideration for initiation of statin therapy even in the high PRS groups.PMID:35952728 | DOI:10.1016/j.pcad.2022.08.003
Source: Atherosclerosis - August 11, 2022 Category: Cardiology Authors: Mahmoud Al Rifai Jie Yao Xiuqing Guo Wendy S Post Shaista Malik Roger S Blumenthal Christie M Ballantyne Matthew Budoff Kent D Taylor Henry J Lin Stephen S Rich Catherine Hajek Philip Greenland Jerome I Rotter Salim S Virani Source Type: research

Alcohol-Mediated Changes in Left Atrial Size in Coronary Heart Disease Patients
Epidemiologic studies of the relationship between alcohol use and risk of cardiovascular outcomes in non–coronary heart disease (non-CHD)–specific populations have typically identified a U-shaped relationship. A consistent finding among these studies is that light to moderate alcohol consumption is inversely associated with all-cause and cardiovascular mortality. Additional potentially beneficial effects identified include favorable changes in levels of high-density lipoprotein cholesterol, fibrinogen, platelet aggregation, and lipoprotein(a). Conversely, alcohol use is well known to increase blood pressure, itself a r...
Source: Journal of Cardiac Failure - March 1, 2013 Category: Cardiology Authors: Usha B. Tedrow Tags: Editorial Comment Source Type: research

Systolic and diastolic component of orthostatic hypotension and cardiovascular events in hypertensive patients: the Captopril Prevention Project
Conclusion: Orthostatic hypotension has a dual role in cardiovascular events among hypertensive patients: SBP fall indicates higher risk of stroke, whereas DBP fall confers higher risk of MI.
Source: Journal of Hypertension - December 17, 2013 Category: Cardiology Tags: ORIGINAL PAPERS: Orthostatic hypotension Source Type: research

Systolic and diastolic component of orthostatic hypotension and cardiovascular events in hypertensive patients: the Captopril Prevention Project
Conclusion:Orthostatic hypotension has a dual role in cardiovascular events among hypertensive patients: SBP fall indicates higher risk of stroke, whereas DBP fall confers higher risk of MI.
Source: Journal of Hypertension - December 18, 2013 Category: Cardiology Tags: ORIGINAL PAPERS: Orthostatic hypotension Source Type: research

Dyslipidaemia in patients with established cardiovascular disease in Sub-Saharan Africa: a systematic review and meta-analysis
Dyslipidaemia has been recognized as a major risk factor for cardiovascular diseases. Our objectives were to conduct a systematic review and meta-analysis of published studies to determine the prevalence of dyslipidaemia among hospitalized adult patients with cardiovascular disease in sub-Saharan Africa and to compare between the various cardiovascular disease types. We searched Internet-based search tools and other sources for studies on dyslipidaemia or hypercholesterolaemia among hospitalized adult patients with established cardiovascular disease in sub-Saharan Africa, from 1985 to May 2011. Established cardiovascular d...
Source: European Journal of Preventive Cardiology - May 27, 2014 Category: Cardiology Authors: Karaye, K. M., Habib, A. G. Tags: Review Source Type: research

Impact of Hypertension and Subclinical Organ Damage on the Incidence of Cardiovascular Disease Among Japanese Residents at the Population and Individual Levels  - The Circulatory Risk in Communities Study (CIRCS).
CONCLUSIONS: HT and hypertensive subclinical organ damage are significantly associated with incident stroke and CAD at the population level, suggesting that management of HT and assessment of subclinical organ damage in hypertensive subjects at a screening program are still beneficial for community-based CVD prevention. PMID: 28367846 [PubMed - as supplied by publisher]
Source: Circulation Journal - March 29, 2017 Category: Cardiology Authors: Kitamura A, Yamagishi K, Imano H, Kiyama M, Cui R, Ohira T, Umesawa M, Muraki I, Sankai T, Saito I, Iso H, CIRCS Investigators Tags: Circ J Source Type: research

Non-High-Density Lipoprotein Cholesterol and Risk of Cardiovascular disease: the Japan Epidemiology Collaboration on Occupational Health Study
CONCLUSIONS: High non-HDL-C levels were associated with an increased risk of myocardial infarction. Moreover, high and low non-HDL-C levels were associated with a high risk of stroke and its subtypes among Japanese workers.PMID:34690212 | DOI:10.5551/jat.63118
Source: Journal of Atherosclerosis and Thrombosis - October 25, 2021 Category: Cardiology Authors: Huan Hu Ami Fukunaga Toshitaka Yokoya Tohru Nakagawa Toru Honda Shuichiro Yamamoto Hiroko Okazaki Toshiaki Miyamoto Naoko Sasaki Takayuki Ogasawara Naoki Gonmori Kenya Yamamoto Ai Hori Kentaro Tomita Satsue Nagahama Maki Konishi Nobumi Katayama Hisayoshi Source Type: research