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Condition: Hypothermia
Procedure: Perfusion
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Total 64 results found since Jan 2013.
Left ventricular assist device implantation combined with hemiarch replacement for severe aortic atherosclerosis
J Thorac Dis. 2023 Jul 31;15(7):3979-3983. doi: 10.21037/jtd-23-255. Epub 2023 Jul 6.ABSTRACTImplantation of the left ventricular assist device (LVAD) has emerged as a widely employed therapeutic approach for specifically chosen individuals suffering from severe heart failure. Stroke is a well-known complication of LVAD implantation. Concomitant aortic surgeries in patients requiring LVAD implantation to avoid outflow graft anastomosis to a severe atherosclerotic aorta are unknown. We illustrate a successful LVAD implantation with hemiarch replacement for severe aortic atherosclerosis to decrease the risk of postoperative ...
Source: Atherosclerosis - August 10, 2023 Category: Cardiology Authors: June Lee Seok Beom Hong Yong Han Kim Hwan Wook Kim Do Yeon Kim Source Type: research
Selective intraarterial hypothermia combined with mechanical thrombectomy for acute cerebral infarction based on microcatheter technology: A single-center, randomized, single-blind controlled study
ConclusionMechanical thrombectomy combined with intraarterial cold saline perfusion is a safe and effective measure for the treatment of acute cerebral infarction. Postoperative NIHSS scores and infarct volumes were significantly improved with this strategy compared with simple mechanical thrombectomy, and the 90-day good prognosis rate was improved. The mechanism by which this treatment exerts its cerebral protective effect may be by inhibiting the transformation of the ischaemic penumbra of the infarct core area, scavenging some oxygen free radicals, reducing inflammatory injury to cells after acute infarction and ischae...
Source: Frontiers in Neurology - February 16, 2023 Category: Neurology Source Type: research
The intra-arterial selective cooling infusion system: A mathematical temperature analysis and in vitro experiments for acute ischemic stroke therapy
CONCLUSION: This prototype instrument system could safely cool simulated blood in vitro and reperfuse it to the target cerebral blood vessel. This technique could promote the clinical application of an autologous blood perfusion system for stroke therapy.PMID:35702957 | DOI:10.1111/cns.13883
Source: CNS Neuroscience and Therapeutics - June 15, 2022 Category: Neuroscience Authors: Miaowen Jiang Ming Li Yuan Gao Longfei Wu Wenbo Zhao Chuanhui Li Chengbei Hou Zhengfei Qi Kun Wang Shiqiang Zheng Zhichen Yin Chuanjie Wu Xunming Ji Source Type: research
Aortic arch repair: lessons learned over three decades at Baylor College of Medicine
J Cardiovasc Surg (Torino). 2022 May 27. doi: 10.23736/S0021-9509.22.12376-1. Online ahead of print.ABSTRACTThe treatment of complex aortic arch disease continues to be among the most demanding cardiovascular operations, with a considerable risk of death and stroke. Since January 1990, our single-practice service has performed over 3,000 repairs of the aortic arch. Our aim is to describe the progression of our technical approach to open aortic arch repair. Our center's surgical technique has evolved considerably over the last three decades. When it comes to initial arterial cannulation, we have shifted away from femoral ar...
Source: The Journal of Cardiovascular Surgery - May 27, 2022 Category: Cardiovascular & Thoracic Surgery Authors: Arsalan Amin Ginger M Etheridge Hiruni S Amarasekara Susan Y Green Joseph S Coselli Source Type: research
What are Some Risk Factors for Hypoxic-Ischemic Encephalopathy Outcomes?
Discussion
“Neonatal encephalopathy, manifesting as altered responsiveness, seizures, apnea and abnormal muscle tone and reflexes, resulting from hypoxic-ischemic injury is termed hypoxic-ischemic encephalopathy (HIE).” Neonatal encephalopathy can be associated with other problems including stroke, hemorrhage, infection, pre-term brain injury and hypoglycemia as some examples. Sometimes more than one of these entities occurs simultaneously such as hypoglycemia and HIE. HIE can result in long-term neurological problems including motor, behavioral, and cognitive problems that can become apparent even years later....
Source: PediatricEducation.org - December 13, 2021 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
Hypothermia Promotes Mitochondrial Elongation In Cardiac Cells Via Inhibition Of Drp1
In conclusion hypothermia promoted elongation of cardiac mitochondria via reduced pDrp1S616 abundance which was also associated with suppression of cellular oxygen consumption. Silencing of TRPV1 in H9c2 cardiomyocytes reproduced the morphological and respirometric phenotype of hypothermia. This report demonstrates a novel mechanism of cold-induced inhibition of mitochondrial fission.PMID:34331901 | DOI:10.1016/j.cryobiol.2021.07.013
Source: Cryobiology - July 31, 2021 Category: Biology Authors: David Taylor Juliana Germano Yang Song Hanane Hadj-Moussa Stefanie Marek-Iannucci Raeesa Dhanji Jon Sin Lawrence S C Czer Kenneth B Storey Roberta A Gottlieb Source Type: research
Early and long-term results of hypothermic circulatory arrest in aortic surgery: a 20-year single-centre experience
Aims
The aim of this study was to document the postoperative outcomes of patients who underwent hypothermic circulatory arrest (HCA), the evolution of HCA management over time and to identify the risks factor for early mortality and postoperative stroke.
Methods
Four hundred and twenty-four patients who underwent aortic surgery with HCA at our institution between January 1995 and June 2016 were consecutively included.
Results
The main indications were degenerative aneurysm (254; 59.9%) and acute type A aortic dissection (146; 34.4%). Interventions were performed under deep (18.4 ± 0.9°C; n = 350...
Source: Journal of Cardiovascular Medicine - June 15, 2021 Category: Cardiology Tags: Research articles: Valvular heart disease Source Type: research
