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Specialty: Cardiology
Condition: Heart Failure

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Total 4537 results found since Jan 2013.

HFpEF Is the Substrate for Stroke in Obesity and Diabetes Independent of Atrial Fibrillation
Publication date: Available online 6 November 2019Source: JACC: Heart FailureAuthor(s): Milton PackerAbstractBoth obesity and type 2 diabetes are important risk factors for the development of heart failure with a preserved ejection fraction (HFpEF), and both disorders increase the risk of systemic thromboembolic events. Traditionally, the risk of stroke has been explained by the strong association of these disorders with atrial fibrillation (AF). However, adiposity and diabetes are risk factors for systemic thromboembolism, even in the absence of AF, because both can lead to the development of an inflammatory and fibrotic ...
Source: JACC: Heart Failure - November 8, 2019 Category: Cardiology Source Type: research

HFpEF Is the Substrate for Stroke in Obesity and Diabetes Independent of Atrial Fibrillation
Publication date: January 2020Source: JACC: Heart Failure, Volume 8, Issue 1Author(s): Milton PackerAbstractBoth obesity and type 2 diabetes are important risk factors for the development of heart failure with a preserved ejection fraction (HFpEF), and both disorders increase the risk of systemic thromboembolic events. Traditionally, the risk of stroke has been explained by the strong association of these disorders with atrial fibrillation (AF). However, adiposity and diabetes are risk factors for systemic thromboembolism, even in the absence of AF, because both can lead to the development of an inflammatory and fibrotic a...
Source: JACC: Heart Failure - December 31, 2019 Category: Cardiology Source Type: research

Prognostic Value of Serum N-Terminal Pro-Brain Natriuretic Peptide Level over Heart Failure for Stroke Events and Deaths in Patients with Atrial Fibrillation.
Authors: Kuronuma K, Okumura Y, Morikawa T, Yokoyama K, Matsumoto N, Tachibana E, Oiwa K, Matsumoto M, Kojima T, Haruta H, Nomoto K, Sonoda K, Arima K, Kogawa R, Takahashi F, Kotani T, Ohkubo K, Fukushima S, Itou S, Kondo K, Chiku M, Ohno Y, Onikura M, Hirayama A, SAKURA AF Registry Investigators Abstract Atrial fibrillation (AF) and heart failure (HF) often coexist. The aims of this study were to explore the factors associated with the serum levels of N-terminal pro-brain natriuretic peptide (NT-proBNP), and the association between prognosis and a history of HF or the serum NT-proBNP level in Japanese patients wit...
Source: International Heart Journal - May 20, 2020 Category: Cardiology Tags: Int Heart J Source Type: research

Endocardial versus epicardial left atrial appendage exclusion for stroke prevention in patients with atrial fibrillation: mid ‐term follow‐up
ConclusionEndocardial and Epicardial LAAC techniques shows comparable implantation outcomes and safety profile and stroke prevention in patients with AF. Future randomized studies are needed to corroborate these initial results and assess long term mortality.This article is protected by copyright. All rights reserved.
Source: Journal of Cardiovascular Electrophysiology - November 4, 2020 Category: Cardiology Authors: Radoslaw Litwinowicz, Marian Burysz, Piotr Mazur, Boguslaw Kapelak, Magdalena Bartus, Dhanunjaya Lakkireddy, Randall J Lee, Michalina Malec ‐Litwinowicz, Krzysztof Bartus Tags: ORIGINAL ARTICLES Source Type: research

Endocardial versus epicardial left atrial appendage exclusion for stroke prevention in patients with atrial fibrillation: Midterm follow ‐up
ConclusionEndocardial and Epicardial LAAC techniques show comparable implantation outcomes and safety profile and stroke prevention in patients with AF. Future randomized studies are needed to corroborate these initial results and assess long term mortality.
Source: Journal of Cardiovascular Electrophysiology - November 11, 2020 Category: Cardiology Authors: Radoslaw Litwinowicz, Marian Burysz, Piotr Mazur, Boguslaw Kapelak, Magdalena Bartus, Dhanunjaya Lakkireddy, Randall J. Lee, Michalina Malec ‐Litwinowicz, Krzysztof Bartus Tags: ORIGINAL ARTICLES Source Type: research

Determinants and consequences of heart rate and stroke volume response to exercise in patients with heart failure and preserved ejection fraction
ConclusionThe hemodynamic response to exercise was very heterogenous among patients with HFpEF, with chronotropic incompetence observed in up to 56% and 28% had impaired increase in SVI. This suggests that hemodynamic exercise testing may be useful to identify which HFpEF patients may benefit from interventions targeting stroke volume and chronotropic response.Clinical Trial RegistrationClincaltrial.gov (NCT01913613, NCT02600234, NCT01974557)
Source: European Journal of Heart Failure - March 9, 2021 Category: Cardiology Authors: Emil Wolsk, David M. Kaye, Jan Komtebedde, Sanjiv J. Shah, Barry A. Borlaug, Daniel Burkhoff, Dalane W. Kitzman, John G. Cleland, Gerd Hasenfu ß, Christian Hassager, Jacob E. Møller, Finn Gustafsson Tags: Research Article Source Type: research

Dabigatran for stroke prevention in real life in a sample of population from Turkey: D-SPIRIT registry
CONCLUSION: This registry obtained an important overview of the current safety and effectiveness of the dabigatran etexilate in Turkey. Our results indicate similar rates of thromboembolic and bleeding events with pivotal phase 3 trial and other real-life registries. However, rate of undertreatment usage of dabigatran etexilate in real life was found to be considerable.PMID:34881702 | DOI:10.5543/tkda.2021.07734
Source: Turk Kardiyoloji Dernegi arsivi - December 9, 2021 Category: Cardiology Authors: Cihan Alt ın Caner Topalo ğlu Nurullah Çetin Onur Dalg ıç Veysel Yavuz Emin Alio ğlu Nazile Bilgin Cenk Ekmek çi Nihat Pekel Mehmet Emre Özpelit E şref Tunçer Ebru İpek Türkoğlu Kamil T ülüce Umut Kocaba ş K ıvanç Yüksel U ğur Önsel T Source Type: research

Heart Failure and Ischemic Stroke: A Bidirectional and Multivariable Mendelian Randomization Study
Conclusion: This MR analysis provided evidence of the causal links between genetically predicted HF and IS. Subgroup analysis highlighted the causal or suggestive relationship between genetically predicted HF and LAS or CES. The potential causal links need further investigation with genetic information about other ancestries or etiologies of HF.PMID:34912375 | PMC:PMC8666512 | DOI:10.3389/fgene.2021.771044
Source: Atherosclerosis - December 16, 2021 Category: Cardiology Authors: Luyang Zhang Weishi Liu Wenxian Sun Xin Wang Mengke Tian Lu-Lu Pei Kai Liu Jing Liang Lue Zhou Jie Lu Mingming Ning Ferdinando S Buonanno Yuming Xu Bo Song Source Type: research

Risk of left atrial appendage thrombus and stroke in patients with atrial fibrillation and mitral regurgitation
Conclusions Among patients with NVAF, the presence or severity of MR was not associated with a decreased risk of LAAT or stroke.
Source: Heart - December 10, 2021 Category: Cardiology Authors: Melduni, R., Nkomo, V. T., Wysokinski, W., Gersh, B. J., Deshmukh, A., Padang, R., Greene, E. L., Oh, J. K., Lee, H.-C. Tags: Arrhythmias and sudden death Source Type: research

Dabigatran for stroke prevention in real life in a sample of population from Turkey: D-SPIRIT registry
CONCLUSION: This registry obtained an important overview of the current safety and effectiveness of the dabigatran etexilate in Turkey. Our results indicate similar rates of thromboembolic and bleeding events with pivotal phase 3 trial and other real-life registries. However, rate of undertreatment usage of dabigatran etexilate in real life was found to be considerable.PMID:34881702 | DOI:10.5543/tkda.2021.07734
Source: Turk Kardiyoloji Dernegi arsivi - December 9, 2021 Category: Cardiology Authors: Cihan Alt ın Caner Topalo ğlu Nurullah Çetin Onur Dalg ıç Veysel Yavuz Emin Alio ğlu Nazile Bilgin Cenk Ekmek çi Nihat Pekel Mehmet Emre Özpelit E şref Tunçer Ebru İpek Türkoğlu Kamil T ülüce Umut Kocaba ş K ıvanç Yüksel U ğur Önsel T Source Type: research

Heart Failure and Ischemic Stroke: A Bidirectional and Multivariable Mendelian Randomization Study
Conclusion: This MR analysis provided evidence of the causal links between genetically predicted HF and IS. Subgroup analysis highlighted the causal or suggestive relationship between genetically predicted HF and LAS or CES. The potential causal links need further investigation with genetic information about other ancestries or etiologies of HF.PMID:34912375 | PMC:PMC8666512 | DOI:10.3389/fgene.2021.771044
Source: Atherosclerosis - December 16, 2021 Category: Cardiology Authors: Luyang Zhang Weishi Liu Wenxian Sun Xin Wang Mengke Tian Lu-Lu Pei Kai Liu Jing Liang Lue Zhou Jie Lu Mingming Ning Ferdinando S Buonanno Yuming Xu Bo Song Source Type: research