Heart Failure and Ischemic Stroke: A Bidirectional and Multivariable Mendelian Randomization Study

Conclusion: This MR analysis provided evidence of the causal links between genetically predicted HF and IS. Subgroup analysis highlighted the causal or suggestive relationship between genetically predicted HF and LAS or CES. The potential causal links need further investigation with genetic information about other ancestries or etiologies of HF.PMID:34912375 | PMC:PMC8666512 | DOI:10.3389/fgene.2021.771044

Source: Atherosclerosis - December 16, 2021 Category: Cardiology Authors: Luyang Zhang Weishi Liu Wenxian Sun Xin Wang Mengke Tian Lu-Lu Pei Kai Liu Jing Liang Lue Zhou Jie Lu Mingming Ning Ferdinando S Buonanno Yuming Xu Bo Song Source Type: research