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Condition: Heart Failure
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Total 212 results found since Jan 2013.

Outcomes of Berlin Heart EXCOR ® pediatric ventricular assist device support in patients with restrictive and hypertrophic cardiomyopathy
This study reviews the North American experience with Berlin Heart EXCOR® ventricular assist device implants in children with such physiology. The Berlin Heart clinical database was reviewed. Patients with primary diastolic dysfunction are included in this study. Twenty pediatric patients with restrictive cardiomyopathy (n = 13), hypertrophic cardiomyopathy (n = 3), or congenital heart disease with restrictive physiology (n = 4) who were supported with EXCOR® were identified. Of these, nine (45%) were successfully bridged to transplant, one (5%) weaned from support, and 10 (50%) died after support was withdrawn. Of...
Source: Pediatric Transplantation - September 1, 2017 Category: Transplant Surgery Authors: Jennifer A. Su, Jondavid Menteer Tags: ORIGINAL ARTICLE Source Type: research

Associations between Ambient Fine Particulate Oxidative Potential and Cardiorespiratory Emergency Department Visits
Conclusions: Lag 0–2 OPDTT was associated with ED visits for multiple cardiorespiratory outcomes, providing support for the utility of OPDTT as a measure of fine particle toxicity. https://doi.org/10.1289/EHP1545 Received: 23 December 2016 Revised: 4 August 2017 Accepted: 12 August 2017 Published: 26 October 2017 Please address correspondence to J.Y. Abrams, Centers for Disease Control and Prevention, NCEZID/DHCPP, 1600 Clifton Rd. NE, CDC Mailstop A30, Atlanta, GA 30333 USA. Telephone: (404) 639-5121. Email: jabrams@cdc.gov Supplemental Material is available online (https://doi.org/10.1289/EHP1545). The authors ...
Source: EHP Research - October 26, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Heart Failure with Preserved Ejection Fraction: Diagnosis and Management.
Abstract Heart failure with preserved ejection fraction, also referred to as diastolic heart failure, causes almost one-half of the 5 million cases of heart failure in the United States. It is more common among older patients and women, and results from abnormalities of active ventricular relaxation and passive ventricular compliance, leading to a decline in stroke volume and cardiac output. Heart failure with preserved ejection fraction should be suspected in patients with typical symptoms (e.g., fatigue, weakness, dyspnea, orthopnea, paroxysmal nocturnal dyspnea, edema) and signs (S3 heart sound, displaced apica...
Source: American Family Physician - November 1, 2017 Category: Primary Care Authors: Gazewood JD, Turner PL Tags: Am Fam Physician Source Type: research

Examination of heart failure as a predictor of driving cessation
The objective of these analyses is to examine HF as an independent predictor of driving cessation across three years among a cohort of older drivers in the United States. Analyses included 850 older adults who completed sensory, cognitive, and physical measures at baseline and mobility and health measures at a three-year follow-up. Cox regression was used to examine the effects of HF, stroke, vision, cognition, and physical function as predictors of incident driving cessation over three years. Participants with HF were over three times more likely to cease driving, HR = 3.19, 95% CI [1.27, 8.02], p = .014. However, HF was ...
Source: Journal of Transport and Health - November 19, 2017 Category: Occupational Health Source Type: research

Efficacy and Efficiency of Perioperative Stellate Ganglion Blocks in Cardiac Surgery: A Pilot Study
Nationally, postoperative atrial fibrillation (POAF) occurs in up to 40% of patients after coronary artery bypass grafting (CABG), 50% of patients after valve surgery, 64% of patients after mitral valve and CABG, and 49% after aortic valve replacement.1 Atrial fibrillation worsens a patient ’s hemodynamic status and increases the risk of congestive heart failure, embolic events, and longer intensive care unit stays, leading to increased patient morbidity and strain on financial resources. In the United States, POAF carries a higher risk of stroke, worsened survival, and an additional 4.9 days and $10,000 to $11,500 in hospital stay costs.
Source: Journal of Cardiothoracic and Vascular Anesthesia - November 20, 2017 Category: Anesthesiology Authors: Christopher W. Connors, Wendy Y. Craig, Scott A. Buchanan, Justin M. Poltak, James B. Gagnon, Craig S. Curry Tags: Letter to the Editor Source Type: research

Contribution of cardiac and extra ‐cardiac disease burden to risk of cardiovascular outcomes varies by ejection fraction in heart failure
ConclusionIn North American HF patients enrolled in the CHARM trials, the relative contribution of cardiac and extra‐cardiac disease burden to CV outcomes and death differed depending on LVEF. The high risk of events attributable to non‐cardiac disease burden may help explain why cardiac disease‐modifying medication proven to be efficacious in HFrEF patients has not proven beneficial in HFpEF.
Source: European Journal of Heart Failure - November 1, 2017 Category: Cardiology Authors: Emil Wolsk, Brian Claggett, Lars K øber, Stuart Pocock, Salim Yusuf, Karl Swedberg, John J.V. McMurray, Christopher B. Granger, Marc A. Pfeffer, Scott D. Solomon Tags: Research Article Source Type: research

Impact of testosterone replacement therapy on thromboembolism, heart disease, and obstructive sleep apnea in men
ConclusionsThis study adds to growing evidence that cardiovascular risk from TRT may be less than once feared. The increased risk of sleep apnea in men using TRT is noteworthy. The study strengths include the large number of healthy and young men exposed to TRT. Limitations include the retrospective study design inability to account for granular details of TRT use such as dosage, specific forms of TRT and serum testosterone levels pre‐ and post‐TRT.This article is protected by copyright. All rights reserved.
Source: BJU International - January 31, 2018 Category: Urology & Nephrology Authors: Alexander P Cole, Julian Hanske, Wei Jiang, Nicollette K. Kwon, Stuart R Lipsitz, Martin N Kathrins, Peter A Learn, Maxine Sun, Adil H Haider, Shehzad S Basaria, Quoc ‐Dien Trinh Tags: Original Article Source Type: research

Alcohol and CV Health: Jekyll and Hyde J-Curves
A routine of light or moderate alcohol consumption ( ≤1 drink/day for women and 1 to 2 drinks/day for men) were associated with a lower risk for all-cause mortality, coronary artery disease (CAD), type 2 diabetes mellitus (T2D), heart failure (HF), and stroke. Conversely, heavy drinking, (>4 drinks/day) is associated with an increased risk for death and cardiovascular (CV) disease (CVD). Excessive alcohol intake trails behind only smoking and obesity among the 3 leading causes of premature deaths in the United States (US).
Source: Progress in Cardiovascular Diseases - February 17, 2018 Category: Cardiology Authors: Evan L. O'Keefe, James J. Di Nicolantonio, James H. O'Keefe, Carl J. Lavie Source Type: research

Hospitalizations for cardiovascular disease after liver transplantation in the United States
Conclusions: CVD after liver transplant is evolving and responsible for growing rates of inpatient care. Transplant hospitals are associated with poor outcomes, even after risk adjustment for patient and hospital characteristics, which may be attributable to selective referral of certain patient phenotypes, but could also be related to differences in quality of care. Further study is warranted. This article is protected by copyright. All rights reserved.
Source: Liver Transplantation - March 15, 2018 Category: Transplant Surgery Authors: Narjeet S. Khurmi, Yu ‐Hui Chang, D. Eric Steidley, Andrew L. Singer, Winston R. Hewitt, Kunam S. Reddy, Adyr A. Moss, Amit K. Mathur Tags: Original Article Source Type: research

Long-Term Cognitive Decline After Newly Diagnosed Heart Failure: Longitudinal Analysis in the CHS (Cardiovascular Health Study) Original Articles
Conclusions: Decline in global cognitive ability tends to be faster after HF diagnosis than without HF. Clinical and public health implications of this finding warrant further attention.
Source: Circulation: Heart Failure - March 9, 2018 Category: Cardiology Authors: Hammond, C. A., Blades, N. J., Chaudhry, S. I., Dodson, J. A., Longstreth, W. T., Heckbert, S. R., Psaty, B. M., Arnold, A. M., Dublin, S., Sitlani, C. M., Gardin, J. M., Thielke, S. M., Nanna, M. G., Gottesman, R. F., Newman, A. B., Thacker, E. L. Tags: Clinical Studies, Epidemiology, Heart Failure Original Articles Source Type: research

Laparoscopic Sleeve Gastrectomy in Patients with Heart Failure and Left Ventricular Assist Devices as a Bridge to Transplant
Obesity is an epidemic that is progressive, costly, and closely associated with cardiac disease and death. Obesity causes structural and functional changes in the heart due to increases in metabolic demand, total blood volume, and stroke volume, all of which cause left ventricular dilation, cardiac muscle hypertrophy, and atrial enlargement [1,2]. Heart failure is a deadly condition, affecting up to 5.8 million people in the United States with associated health care costs exceeding 30 billion dollars per year [3,4].
Source: Surgery for Obesity and Related Diseases - April 18, 2018 Category: Surgery Authors: Russell B Hawkins, Kristina Go, Steven L Raymond, Alexander Ayzengart, Jeffrey Friedman Source Type: research

Alcohol and CV Health: Jekyll and Hyde J-Curves
A routine of light or moderate alcohol consumption ( ≤1 drink/day for women and 1 to 2 drinks/day for men) were associated with a lower risk for all-cause mortality, coronary artery disease (CAD), type 2 diabetes mellitus (T2D), heart failure (HF), and stroke. Conversely, heavy drinking, (>4 drinks/day) is associated with an increased risk for death and cardiovascular (CV) disease (CVD). Excessive alcohol intake trails behind only smoking and obesity among the 3 leading causes of premature deaths in the United States (US).
Source: Progress in Cardiovascular Diseases - February 17, 2018 Category: Cardiology Authors: Evan L. O'Keefe, James J. Di Nicolantonio, James H. O'Keefe, Carl J. Lavie Source Type: research

International Study of Comparative Health Effectiveness with Medical and Invasive Approaches (ISCHEMIA) trial: Rationale and design
Conclusions ISCHEMIA will provide new scientific evidence regarding whether an invasive management strategy improves clinical outcomes when added to optimal medical therapy in patients with SIHD and moderate or severe ischemia.
Source: American Heart Journal - May 26, 2018 Category: Cardiology Source Type: research

Hypertension guideline update: A new guideline for a new era
This article reviews the ACC/AHA Task Force on Clinical Practice Guidelines' 2017 Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults. Key changes include reclassification of BP stages and lowering of hypertension treatment goals.
Source: Journal of the American Academy of Physician Assistants - May 29, 2018 Category: Primary Care Tags: CME: Cardiovascular Medicine Source Type: research