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Total 541 results found since Jan 2013.
Janssen Announces U.S. FDA Approval of PONVORY ™ (ponesimod), an Oral Treatment for Adults with Relapsing Multiple Sclerosis Proven Superior to Aubagio® (teriflunomide) in Reducing Annual Relapses and Brain Lesions
TITUSVILLE, N.J. – (March 19, 2021) – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced that the U.S. Food and Drug Administration (FDA) approved PONVORY™ (ponesimod), a once-daily oral selective sphingosine-1-phosphate receptor 1 (S1P1) modulator, to treat adults with relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease and active secondary progressive disease.1,2,3 PONVORY™ offers MS patients superior efficacy in reducing annualized relapse rates compared to an established oral therapy and a proven safety profile backed by ove...
Source: Johnson and Johnson - March 19, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news
Incidence of Cognitive Impairment during Aging in Rural South Africa: Evidence from HAALSI, 2014 to 2019
Conclusions: This study presents some of the first incidence rate estimates for aging-related cognitive impairment in rural South Africa. Social disparities in incident cognitive impairment rates were apparent in patterns similar to those observed in many high-income countries.Neuroepidemiology
Source: Neuroepidemiology - March 3, 2021 Category: Epidemiology Source Type: research
Prevalence of overweight and obesity and associated factors among women of childbearing age in Brazil.
CONCLUSION: The results showed an association between excess weight and sociodemographic factors, both determinants of general and reproductive health history. Implementation of effective public health policies is necessary to prevent unfavorable outcomes related to the health of women of childbearing age with excess weight.
PMID: 33500016 [PubMed - as supplied by publisher]
Source: Public Health Nutrition - January 27, 2021 Category: International Medicine & Public Health Authors: Lyrio AO, Souza ES, Conceição SDS, Batista JET, Brito SM, Gomes Filho IS, Figueiredo ACMG, da Cruz SS Tags: Public Health Nutr Source Type: research
Healthcare in transition in the Republic of Armenia: the evolution of emergency medical systems and directions forward
AbstractArmenia, an ex-Soviet Republic in transition since independence in 1991, has made remarkable strides in development. The crisis of prioritization that has plagued many post-Soviet republics in transition has meant differential growth in varied sectors in Armenia. Emergency systems is one of the sectors which is neglected in the current drive to modernize. The legacy of the Soviet Semashko system has left a void in specialized care including emergency care. This manuscript is a descriptive overview of the current state of emergency care in Armenia using in-depth key informant interviews and review of published and u...
Source: International Journal of Emergency Medicine - January 12, 2021 Category: Emergency Medicine Source Type: research
IJERPH, Vol. 18, Pages 612: Effects of Behavioral Risk Factors and Social-Environmental Factors on Non-Communicable Diseases in South Korea: A National Survey Approach
This study investigates the effects of social-environmental and behavioral risk factors on NCDs as well as the effects of social-environmental factors on behavioral risk factors using an integrated research model. This study used a dataset from the 2017 Korea National Health and Nutrition Examination Survey. After filtering incomplete responses, 5462 valid responses remained. Items including one’s social-environmental factors (household income, education level, and region), behavioral factors (alcohol use, tobacco use, and physical activity), and NCDs histories were used for analyses. To develop a comprehensi...
Source: International Journal of Environmental Research and Public Health - January 12, 2021 Category: Environmental Health Authors: Nam Jeong Jeong Eunil Park Angel P. del del Pobil Tags: Article Source Type: research
Approaches in Prehospital Sepsis Screening
Discussion
In the United States, sepsis is one of the leading causes of death, which requires timely identification and proper treatment (CDC, 2019; Guerra et al., 2020; Polito et al., 2015). Based upon a review of literature conducted from 2014 to 2018, the primary investigators could locate five prehospital EMS screening tools to assist EMS providers in identifying at-risk sepsis patients. The researchers explored how the modified SIRS and qSOFA scoring systems were used in hospital settings in addition to these five prehospital EMS screening tools.
The Bas 90-30-90, Guerra, PRESEP, PRESS, and Robson tools have ove...
Source: JEMS Operations - January 5, 2021 Category: Emergency Medicine Authors: JEMS Staff Tags: Exclusives Patient Care EMS EMT Paramedic Prehospital Sepsis Source Type: news
How Good is Photoscreening For Young Children ’ s Vision Problems?
This study showed that not only was smartphone photoscreening feasible, but was quite good at screening for potential vision problems. Smartphone photoscreening has the advantages of being more ubiquitously available and thus children in almost any location can be screened.
A study of photoscreening using a handheld digital photoscreener in primary care offices validated the technology showing an overall referral rate of 10% to an ophthalmologist with suspected astigmatism, anisometropia and strabismus being the most common reasons. The overall positive predictive rate was 0.60. “…[O]ver 60% of children referre...
Source: PediatricEducation.org - January 4, 2021 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
A prospective study of waist circumference trajectories and incident cardiovascular disease in China: the Kailuan Cohort Study
ConclusionsWC trajectory patterns were associated with altered risk of CVD among Chinese adults, even among people without BMI-defined obesity. When stratifying by age, the association was observed to be higher in younger adults.
Source: American Journal of Clinical Nutrition - December 17, 2020 Category: Nutrition Source Type: research
A prospective study of waist circumference trajectories and incident cardiovascular disease in China: the Kailuan Cohort Study.
CONCLUSIONS: WC trajectory patterns were associated with altered risk of CVD among Chinese adults, even among people without BMI-defined obesity. When stratifying by age, the association was observed to be higher in younger adults.
PMID: 33330917 [PubMed - as supplied by publisher]
Source: The American Journal of Clinical Nutrition - December 17, 2020 Category: Nutrition Authors: Wang L, Lee Y, Wu Y, Zhang X, Jin C, Huang Z, Wang Y, Wang Z, Kris-Etherton P, Wu S, Gao X Tags: Am J Clin Nutr Source Type: research
Number of Social Determinants of Health and Fatal and Nonfatal Incident Coronary Heart Disease in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) Study.
Conclusions: A greater burden of SDH was associated with a graded increase in risk of incident CHD, with greater magnitude and independent associations for fatal incident CHD. Counting the number of SDH may be a promising approach that could be incorporated into clinical care to identify individuals at high risk of CHD.
PMID: 33269599 [PubMed - as supplied by publisher]
Source: Circulation - December 3, 2020 Category: Cardiology Authors: Safford MM, Reshetnyak E, Sterling MR, Richman JS, Muntner PM, Durant RW, Booth J, Pinheiro LC Tags: Circulation Source Type: research
