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Total 340 results found since Jan 2013.

LDL-C target attainment in secondary prevention of ASCVD in the United States: barriers, consequences of nonachievement, and strategies to reach goals
Postgrad Med. 2022 Aug 25. doi: 10.1080/00325481.2022.2117498. Online ahead of print.ABSTRACTAtherosclerotic cardiovascular disease (ASCVD) is the leading cause of death in the United States. Elevated low-density lipoprotein cholesterol (LDL-C) is a major causal risk factor for ASCVD. Current evidence overwhelmingly demonstrates that lowering LDL-C reduces the risk of secondary cardiovascular events in patients with previous myocardial infarction or stroke. There is no lower limit for LDL-C: large, randomized studies and meta-analyses have found continuous benefit and no safety concerns in patients achieving LDL-C levels &...
Source: Postgraduate Medicine - August 25, 2022 Category: Internal Medicine Authors: James Underberg Peter P Toth Fatima Rodriguez Source Type: research

Pregnancy-related cardiovascular conditions and outcomes in a United States Medicaid population
Conclusion This US cohort of Medicaid-funded women have a high incidence of severe cardiovascular conditions during pregnancy. Cardiometabolic conditions of pregnancy conferred threefold higher odds of severe cardiovascular outcomes.
Source: Heart - September 12, 2022 Category: Cardiology Authors: Marschner, S., von Huben, A., Zaman, S., Reynolds, H. R., Lee, V., Choudhary, P., Mehta, L. S., Chow, C. K. Tags: Open access, Editor's choice Cardiac risk factors and prevention Source Type: research

Effect of high-risk factors on postoperative major adverse cardiovascular and cerebrovascular events trends following bariatric surgery in the United States from 2012 to 2019
CONCLUSIONS: MACE following LSG and LRYGB is rare, occurring in 0.1% of patients. Persistently increasing high-risk conditions and demographics has had minimal effect on MACE over time for LSG and LRYGB but has had significant effect on MACE trend over time in SG and RYGB.PMID:36209030 | DOI:10.1016/j.soard.2022.08.014
Source: Surgery for Obesity and Related Diseases : official journal of the American Society for Bariatric Surgery - October 8, 2022 Category: Surgery Authors: Linda Adepoju Denise Danos Christian Green Michael W Cook Philip R Schauer Vance L Albaugh Source Type: research

What to Know About Diabetes and the Risk of Silent Heart Attacks
At first it seemed like a routine call—something the paramedics had dealt with countless times before. A man in his mid-50s was having a heart attack, and his physician had called for emergency support. But when the paramedics arrived, the physician pulled them aside and told them something peculiar: the man had no cardiovascular symptoms whatsoever. The man had come to his doctor’s office because he’d woken early the previous morning sweating and with a sharp pain in his left wrist. These symptoms had quickly subsided and he’d gone back to sleep. Later, after going about his day, he’d visited...
Source: TIME: Health - November 4, 2022 Category: Consumer Health News Authors: Markham Heid Tags: Uncategorized healthscienceclimate heart health Source Type: news

Background rates of adverse events of special interest for COVID-19 vaccine safety monitoring in the United States, 2019-2020
CONCLUSION: AESI background rates varied by database and demographics and fluctuated in March-December 2020, but most returned to pre-pandemic levels after May 2020. It is critical to standardize demographics and consider seasonal and other trends when comparing historical rates with post-vaccination AESI rates in the same database to evaluate COVID-19 vaccine safety.PMID:36404170 | DOI:10.1016/j.vaccine.2022.11.003
Source: Vaccine - November 20, 2022 Category: Allergy & Immunology Authors: Keran Moll Bradley Lufkin Kathryn R Fingar Cindy Ke Zhou Ellen Tworkoski Chianti Shi Shayan Hobbi Mao Hu Minya Sheng Jillian McCarty Shanlai Shangguan Timothy Burrell Yoganand Chillarige Jeff Beers Patrick Saunders-Hastings Stella Muthuri Kathryn Edwards Source Type: research

Hypertension across a woman's lifespan
Hypertension is recognized globally as the leading risk factor for cardiovascular disease morbidity and mortality in women, and considered their “most substantial and neglected health burden” in a recent publication by the Lancet women and cardiovascular disease Commission [1]. Over half of women aged over 55 years of age in the United States are affected by hypertension [2], which represents the most common modifiable risk factor of c ardiovascular disease, including myocardial infarction and stroke [3].
Source: Maturitas - December 6, 2022 Category: Primary Care Authors: Tara D'Ignazio, Sophie Grand'Maison, Lyne B érubé, Jessica Forcillo, Christine Pacheco Tags: Review article Source Type: research

Janssen Data at ASCO GU Support Ambition to Transform Treatment of Prostate and Bladder Cancer Through Precision Medicine and Early Intervention
RARITAN, N.J., February 13, 2023 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced plans to present more than 20 abstracts featuring seven oncology therapies from its robust portfolio and pipeline at the annual American Society of Clinical Oncology (ASCO) Genitourinary (GU) Cancers Symposium, taking place in San Francisco on February 16-18. Building on more than a decade of leadership in the development of medicines for people diagnosed with GU cancers, Janssen will present data demonstrating its ambition to advance patient-centered treatment through precision medicine, real-world evidence a...
Source: Johnson and Johnson - February 13, 2023 Category: Pharmaceuticals Tags: Latest News Source Type: news

Real-World Racial Variation in Treatment and Outcomes Among Patients with Peripheral Artery Disease
ConclusionsResults of this real-world study suggest that Black patients with PAD have higher disease severity at the time of diagnosis and are at increased risk of experiencing adverse outcomes following diagnosis.
Source: Advances in Therapy - March 6, 2023 Category: Drugs & Pharmacology Source Type: research

Young Americans Face Rising Rates of Obesity, High Blood Pressure, Diabetes
MONDAY, March 6, 2023 -- Young adults in the United States carry an increasing burden of heart health risk factors, making it more likely they’ll suffer a heart attack and stroke as they age, a new study warns. More adults ages 20 to 44 are...
Source: Drugs.com - Daily MedNews - March 6, 2023 Category: General Medicine Source Type: news

Real-World Racial Variation in Treatment and Outcomes Among Patients with Peripheral Artery Disease
CONCLUSIONS: Results of this real-world study suggest that Black patients with PAD have higher disease severity at the time of diagnosis and are at increased risk of experiencing adverse outcomes following diagnosis.PMID:36877443 | DOI:10.1007/s12325-023-02465-6
Source: Adv Data - March 6, 2023 Category: Epidemiology Authors: Keith C Ferdinand Kay Sadik Richard Browne Urvi Desai Patrick Lefebvre Dominique Lejeune Malena Mahendran Fran çois Laliberté Lisa Matay David G Armstrong Source Type: research

Single vs Multi-Arterial Grafts for CABG - Analysis of Recent Data
According to the Center for Disease Control and Prevention (CDC) there are 37.3 million people with diabetes mellitus (DM) in the United States.1 The main cause of death for DM patients, type 1 and 2, is coronary artery disease (CAD), with a 2 to 4-fold increased risk of mortality for heart disease.2 The trend of increased morbidity and mortality in DM patients is likely due to its more complex and diffuse CAD pattern.3 Coronary artery bypass grafting (CABG) remains the gold standard when compared to percutaneous coronary intervention (PCI) for CAD in DM with a reduction in mortality, myocardial infarction, and stroke as d...
Source: Journal of Cardiothoracic and Vascular Anesthesia - March 12, 2023 Category: Anesthesiology Authors: Kenneth R. Hassler, Harish Ramakrishna Tags: Expert Review Source Type: research

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