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Milestones in the 20th century.
Authors: Bergmann KC Abstract From its very beginning, the 20th century represented the period of the main breakthrough for allergology as a clinical and scientific entity. The first years of this period were extraordinarily exciting because of the discovery of the anaphylactic reaction in 1902 and its clinical diagnosis as 'local anaphylaxis', 'serum sickness' (1903) or even as 'anaphylactic shock' (1907). The term 'allergy' was coined in 1906 and led to the recognition of allergic diseases as a pathogenetic entity. The first patient organization of hay fever sufferers was founded in Germany in 1900, the same year...
Source: Chemical Immunology and Allergy - December 2, 2014 Category: Allergy & Immunology Tags: Chem Immunol Allergy Source Type: research

Catching allergy by a simple questionnaire
Conclusions These findings show that RAP test can be proposed as an useful tool to be used by physician other than allergists when evaluating patients with rhinitis, suggesting the need of allergy testing.
Source: World Allergy Organization Journal - June 11, 2015 Category: Allergy & Immunology Source Type: research

Can serum white birch (Betula verrucosa) pollen antigen (Bet v 1) immunoglobulin E measurement distinguish between sensitization and allergy?
ConclusionSerum Bet v 1 IgE measurement may be able to differentiate sensitization from allergy in subjects with sensitization to Betulaceae pollen allergens. Thus, Bet v 1 IgE measurement should be considered a useful step in the management of patients with allergic rhinitis due to Betulaceae pollen allergens.
Source: International Forum of Allergy and Rhinology - August 1, 2015 Category: Allergy & Immunology Authors: Giorgio Ciprandi, Paola Comite, Francesca Ferrero, Paola Minale, Susanna Voltolini, Donatella Bignardi, Vincenzo Fontana, Marco Bruzzone, Costantino Troise, Michele Mussap Tags: ORIGINAL ARTICLE Source Type: research

Asthma, hay fever and food allergy are associated with caregiver‐reported speech disorders in US children
ConclusionChildhood asthma, hay fever, and food allergy are associated with increased risk of speech disorder. Future prospective studies are needed to characterize the associations.This article is protected by copyright. All rights reserved.
Source: Pediatric Allergy and Immunology - April 18, 2016 Category: Allergy & Immunology Authors: Mark A. Strom, Jonathan I. Silverberg Tags: Original Article Source Type: research

Improved Diagnosis of the Polysensitized Allergic Rhinitis Patients Using Component Resolved Diagnosis Method.
Abstract Allergy diagnosis needs to be improved in polysensitized patients due to the existence of possible confounding factors in this type of patients. Component resolved diagnosis (CRD) is a new concept in the investigation of polysensitized patients. The aim of this study was to evaluate if the utilization of ImmunoCAP ISAC improve the diagnosis of the polysensitized allergic rhinitis patients. Skin prick test (SPT) to 58 crude allergen extracts and CRD (ImmunoCAP ISAC) were carried out for 5 polysensitized allergic rhinitis patients. Two patients had a shellfish allergy and avoidance of shellfish was the only...
Source: Iranian Journal of Allergy, Asthma and Immunology - March 31, 2016 Category: Allergy & Immunology Authors: Mohamad Yadzir ZH, Bakhtiar F, Misnan R, Abdullah N, Leecyous B, Murad S Tags: Iran J Allergy Asthma Immunol Source Type: research

Asthma, hay fever, and food allergy are associated with caregiver‐reported speech disorders in US children
ConclusionChildhood asthma, hay fever, and food allergy are associated with increased risk of speech disorder. Future prospective studies are needed to characterize the associations.
Source: Pediatric Allergy and Immunology - May 26, 2016 Category: Allergy & Immunology Authors: Mark A. Strom, Jonathan I. Silverberg Tags: Original Article Source Type: research

Asthma, hay fever, and food allergy are associated with caregiver ‐reported speech disorders in US children
ConclusionChildhood asthma, hay fever, and food allergy are associated with increased risk of speech disorder. Future prospective studies are needed to characterize the associations.
Source: Pediatric Allergy and Immunology - May 26, 2016 Category: Allergy & Immunology Authors: Mark A. Strom, Jonathan I. Silverberg Tags: Original Article Source Type: research

Role of food and aeroallergen sensitization in eosinophilic esophagitis in adults.
CONCLUSION: Adults with EoE and IgE-mediated food sensitivity are not phenotypically different than non-food sensitive patients. There is no clear clinical utility in identifying food sensitivity in adults with EoE. Further studies are needed to determine whether aeroallergen sensitivity represents a distinct phenotype of EoE. PMID: 27590636 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - August 29, 2016 Category: Allergy & Immunology Authors: Olson AA, Evans MD, Johansson MW, Kim CH, Manthei DM, Gaumnitz EA, Mathur SK Tags: Ann Allergy Asthma Immunol Source Type: research

Distinct Contributory Factors Determine Basophil-Allergen Sensitivity in Grass Pollen Rhinitis and in Anaphylactic Wasp Venom Allergy
Conclusions: Our results suggest that basophil allergen sensitivity evaluated by flow-cytometric CD63 analysis depends on two distinct contribution factors. In anaphylactic Hymenoptera allergy, the major factor was intrinsic cellular sensitivity, whereas in pollen allergy, the major factor was allergen-specific IgE on the cell surface.Int Arch Allergy Immunol 2016;171:89-101
Source: International Archives of Allergy and Immunology - December 1, 2016 Category: Allergy & Immunology Source Type: research

Decreased Sensitization to Aeroallergens among Southwestern Iranian Male Farmers.
Abstract Farmers are usually exposed to various inhaled allergens like pollens, mites, molds, and animal dander in their working environment which may lead to allergic rhinitis, asthma and urticaria. The purpose of this study was to identify sensitization to various aeroallergens in farmers and their occupational allergy symptoms. This cross sectional study included 103 male farmers and 100 non-farmer healthy controls. The work-related symptoms of farmers were recorded with a questionnaire. Spirometry and skin prick tests with 15 commercial allergen extracts were performed in both farmers and controls. The rate of...
Source: Iranian Journal of Allergy, Asthma and Immunology - August 1, 2017 Category: Allergy & Immunology Authors: Moghtaderi M, Torab Jahromi M, Farjadian S, Ghassemi P, Hosseini Teshnizi S Tags: Iran J Allergy Asthma Immunol Source Type: research

Role of Superantigens in Allergic Inflammation: Their Relationship to Allergic Rhinitis, Chronic Rhinosinusitis, Asthma, and Atopic Dermatitis.
Conclusion Just as SAgs are known to feature in many allergic conditions, they play their part in AR, chronic rhinosinusitis, asthma, and AD. Further research is required before the relationship between SAgs and allergy can be adequately explained. PMID: 30253652 [PubMed - as supplied by publisher]
Source: American Journal of Rhinology and Allergy - September 25, 2018 Category: ENT & OMF Authors: Muluk NB, Altın F, Cingi C Tags: Am J Rhinol Allergy Source Type: research

Recent Advances in Clinical Allergy and Immunology
Allergic diseases are of great concern because of their high prevalence, which is still rising in several regions, their impact on patients ’ physical and psychological health, the huge burden they place on patients’ quality of life, as well as the socioeconomic consequences that they cause. Recent research has provided new data on both genetic and environmental risk factors of atopic/allergic diseases. The application of new techno logies such as “omics” has allowed a better understanding of the pathogenesis and has helped with the identification of therapeutic targets. Immense progress has been made in developing...
Source: International Archives of Allergy and Immunology - November 7, 2018 Category: Allergy & Immunology Source Type: research

The Journal of Allergy and Clinical Immunology: 90 years strong
The Journal of Allergy was launched in November 1929. The inaugural issue had 6 original articles covering asthma, ragweed pollen, bacterial allergy, a case report, sinusitis, and classification of specific sensitivities. The first editorial emphasized that the  Journal “has been launched as a medium for the presentation of papers concerning the clinical aspects of specific hypersensitivities in human beings.”1 Twenty years later, an editorial celebrating that anniversary stated, “A new era in allergy is coming into being, due to the ‘rediscover y’ that human hypersensitiveness may be responsible for the sympt...
Source: Journal of Allergy and Clinical Immunology - October 3, 2019 Category: Allergy & Immunology Authors: Zuhair K. Ballas Tags: Editorial Source Type: research

No allergy left behind – the importance of food allergy in longitudinal cohorts
In recent years, the prevalence of IgE-mediated food allergy appears to be rising. Our ability to confirm this epidemiologic trend is limited. Over the past several decades, multiple cohorts have been established to investigate the etiologic risk factors and natural history of asthma and allergic diseases.1 The allergic march includes the development of eczema, food allergy, allergic rhinitis, and asthma. One of the great tools of clinical epidemiology, the longitudinal cohort, has been successful in describing the allergic march, but this approach has been severely underutilized to study food allergy.
Source: Annals of Allergy, Asthma and Immunology - December 4, 2021 Category: Allergy & Immunology Authors: Lacey B. Robinson, Anna Chen Arroyo, Geneva D. Mehta, Susan A. Rudders, Carlos A. Camargo Source Type: research

Association between latitude and allergic diseases: a longitudinal study from childhood to middle-age.
CONCLUSION: This is the first study, to our knowledge, to demonstrate a differential effect of atopic status on the relationship between latitude and current asthma. Our study demonstrates in a genetically and culturally similar group of individuals that geographic factors may a play role in the development of allergic disease. PMID: 23352525 [PubMed - in process]
Source: Annals of Allergy, Asthma and Immunology - January 30, 2013 Category: Allergy & Immunology Authors: Oktaria V, Dharmage SC, Burgess JA, Simpson JA, Morrison S, Giles GG, Abramson MJ, Walters EH, Matheson MC Tags: Ann Allergy Asthma Immunol Source Type: research