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Condition: Aortic Aneurysm

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Total 540 results found since Jan 2013.

Endovascular treatment of complex diseases of the thoracic aorta-10 years single centre experience.
Conclusions: Treatment of descending aortic diseases by using stent graft implantation has become the method of choice, decreasing the risk of open surgery, especially in patients with severe clinical state and comorbidities. However, effectiveness and safety may be achieved by experience team. PMID: 31372261 [PubMed]
Source: Journal of Thoracic Disease - August 4, 2019 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Rationale for screening selected patients for asymptomatic carotid artery stenosis.
Authors: Paraskevas KI, Eckstein HH, Mikhailidis DP, Veith FJ, Spence JD Abstract Stroke is a leading cause of death and disability worldwide. Approximately 15% of all first-ever strokes occur due to atheroembolism from a previously undetected/untreated asymptomatic carotid stenosis (ACS). Despite that, international guidelines do not recommend screening for ACS. The rationale for not recommending screening include: a) the harm associated with screening, b) the questionable clinical benefit associated with surgery, c) the lack of proven reduction in the risk of stroke, d) the large number of false positive/false ne...
Source: Current Medical Research and Opinion - January 9, 2020 Category: Research Tags: Curr Med Res Opin Source Type: research

Genomic profiling of human vascular cells identifies < i > TWIST1 < /i > as a causal gene for common vascular diseases
by Sylvia T. Nurnberg, Marie A. Guerraty, Robert C. Wirka, H. Shanker Rao, Milos Pjanic, Scott Norton, Felipe Serrano, Ljubica Perisic, Susannah Elwyn, John Pluta, Wei Zhao, Stephanie Testa, YoSon Park, Trieu Nguyen, Yi-An Ko, Ting Wang, Ulf Hedin, Sanjay Sinha, Yoseph Barash, Christopher D. Brown, Thomas Quertermous, Daniel J. Rader Genome-wide association studies have identified multiple novel genomic loci associated with vascular diseases. Many of these loci are common non-coding variants that affect the expression of disease-relevant genes within coronary vascular cells. To identify such genes on a genome-wide level, ...
Source: PLoS Genetics - January 8, 2020 Category: Genetics & Stem Cells Authors: Sylvia T. Nurnberg Source Type: research

Clinical outcomes of endovascular treatment for ruptured thoracic aortic disease.
Conclusions: Endovascular treatment achieves high technical success rates and acceptable clinical outcome. High transfusion volume and low MAP were associated with poor clinical outcomes. PMID: 32264656 [PubMed - as supplied by publisher]
Source: The Korean Journal of Internal Medicine - April 9, 2020 Category: Internal Medicine Authors: Choi JH, Kim SP, Lee HC, Park TS, Park JH, Kim BW, Ahn J, Park JS, Lee HW, Oh JH, Choi JH, Cha KS, Hong TJ Tags: Korean J Intern Med Source Type: research

Open repair of descending thoracic and thoracoabdominal aortic aneurysms: a meta-analysis.
CONCLUSIONS: Despite improvement, open repair of descending thoracic aortic aneurysms and thoracoabdominal aortic aneurysms continues to be associated with a considerable risk of operative death and perioperative complications. The use of the cerebrospinal fluid drain is associated with better outcomes. PMID: 32504596 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - June 2, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Khan FM, Naik A, Hameed I, Robinson NB, Spadaccio C, Rahouma M, Yongle R, Demetres M, Chen H, Chang M, Girardi LN, Gaudino M Tags: Ann Thorac Surg Source Type: research

Perioperative cardiovascular complications rate and activity of coagulation and fibrinolysis among patients undergoing vascular surgery for peripheral artery disease and abdominal aortic aneurysm.
CONCLUSIONS: The study suggests higher activation of coagulation and relatively lower fibrinolytic activity in peripheral artery disease group compared to patients undergoing surgery for abdominal aortic aneurysm without a significant difference in cardiovascular outcomes. PMID: 32600160 [PubMed - as supplied by publisher]
Source: Vascular - June 28, 2020 Category: Surgery Authors: Polok K, Górka J, Fronczek J, Iwaniec T, Górka K, Szczeklik W Tags: Vascular Source Type: research

Genetic predisposition to smoking in relation to 14 cardiovascular diseases
ConclusionThis MR study supports a causal association between smoking and a broad range of CVDs, in particular, coronary artery disease, heart failure, abdominal aortic aneurysm, ischaemic stroke, transient ischaemic attack, peripheral arterial disease, and arterial hypertension.
Source: European Heart Journal - April 16, 2020 Category: Cardiology Source Type: research

Genetic liability to insomnia in relation to cardiovascular diseases: a Mendelian randomisation study
AbstractThe present study aimed to determine the associations between insomnia and cardiovascular diseases (CVDs) using Mendelian randomisation (MR) analysis. As instrumental variables, we used 208 independent single-nucleotide polymorphisms associated with insomnia at the genome-wide significance threshold in a meta-analysis of genome-wide association studies in the UK Biobank and 23andMe including a total of 397  959 self-reported insomnia cases and 933 057 non-cases. Summary-level data for nine CVDs were obtained from the UK Biobank including 367 586 individuals of European ancestry. After correction for multiple tes...
Source: European Journal of Epidemiology - March 12, 2021 Category: Epidemiology Source Type: research

Effectiveness of endovascular versus open surgical repair for thoracic aortic aneurysm: a systematic review and meta-analysis
CONCLUSIONS: Early clinical outcomes including the 30-day mortality, stroke, renal failure, and pulmonary complications significantly favored the TEVAR. However, the mid-to-long-term re-intervention rate favored the OSR and long-term survival was inconsistent among the studies. The quality of evidence was very low. More studies with longer follow-ups are needed. The use of TEVAR should be decided by taking into account other factors including patient characteristics and preferences, cost, and surgeon expertise.PMID:34235903 | DOI:10.23736/S0021-9509.21.11894-4
Source: The Journal of Cardiovascular Surgery - July 8, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Alireza Mahboub-Ahari Fatemeh Sadeghi-Ghyassi Fariba Heidari Source Type: research